3,3′-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway

Modulation of aryl hydrocarbon receptor inhibits esophageal squamous cell carcinoma progression by repressing COX2/PGE2/STAT3 axis

(2020) Peiyao Zhu et al.   Journal of Cell Communication and Signaling

The Aryl Hydrocarbon Receptor Is Expressed in Thyroid Carcinoma and Appears to Mediate Epithelial-Mesenchymal-Transition

(2020) Sonia Moretti et al.   Cancers

Maternal Embryonic Leucine Zipper Kinase Promotes Tumor Growth and Metastasis via Stimulating FOXM1 Signaling in Esophageal Squamous Cell Carcinoma

(2020) Liang Chen et al.   Frontiers in Oncology

SHROOM2 inhibits tumor metastasis through RhoA–ROCK pathway-dependent and -independent mechanisms in nasopharyngeal carcinoma

(2019) Jing Yuan et al.   Cell Death & Disease

Down Regulation of the Expression of ELMO3 by COX2 Inhibitor Suppresses Tumor Growth and Metastasis in Non-Small-Cell Lung Cancer

(2019) Cailong Pan et al.   Frontiers in Oncology

Correlation of the Aryl Hydrocarbon Receptor with FSHR in Ovarian Cancer Patients

(2019) Eileen Deuster et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs)

(2019) Francesca Cirillo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer

(2019) Niranjan Venkateswaran et al.   GENES & DEVELOPMENT

Annexin10 promotes extrahepatic cholangiocarcinoma metastasis by facilitating EMT via PLA2G4A/PGE2/STAT3 pathway

(2019) Rongqi Sun et al.   EBioMedicine

Emerging Role of Migration and Invasion Enhancer 1 (MIEN1) in Cancer Progression and Metastasis

(2019) Prem Prakash Kushwaha et al.   Frontiers in Oncology

Prostaglandin E2 Induces MIR675-5p to Promote Colorectal Tumor Metastasis via Modulation of p53 Expression

(2019) Bo Cen et al.   GASTROENTEROLOGY

Epigenetic Activation of BRCA1 by Genistein In Vivo and Triple Negative Breast Cancer Cells Linked to Antagonism toward Aryl Hydrocarbon Receptor

(2019) Donovan et al.   Nutrients

DLC1 SAM domain-binding peptides inhibit cancer cell growth and migration by inactivating RhoA

(2019) Rakesh Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Esophageal carcinoma: Towards targeted therapies

(2019) Ali Fatehi Hassanabad et al.   CELLULAR ONCOLOGY

Vitamin C Inhibits Triple-Negative Breast Cancer Metastasis by Affecting the Expression of YAP1 and Synaptopodin 2

(2019) Liping Gan et al.   Nutrients

NGF-Enhanced Vasculogenic Properties of Epithelial Ovarian Cancer Cells Is Reduced by Inhibition of the COX-2/PGE2 Signaling Axis

(2019) Maritza P. Garrido et al.   Cancers

3,3′-Diindolylmethane Suppressed Cyprodinil-Induced Epithelial-Mesenchymal Transition and Metastatic-Related Behaviors of Human Endometrial Ishikawa Cells via an Estrogen Receptor-Dependent Pathway

(2018) Bo-Gyoung Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy

(2018) Hongwei Xia et al.   Cell Death & Disease

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition

(2018) Junyi Tang et al.   EXPERIMENTAL CELL RESEARCH

Inflammatory breast cancer: Activation of the aryl hydrocarbon receptor and its target CYP1B1 correlates closely with Wnt5a/b-β-catenin signalling, the stem cell phenotype and disease progression

(2018) Hossam T. Mohamed et al.   Journal of Advanced Research

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Two likely targets for the anti-cancer effect of indole derivatives from cruciferous vegetables: PI3K/Akt/mTOR signalling pathway and the aryl hydrocarbon receptor

(2017) Ada Popolo et al.   SEMINARS IN CANCER BIOLOGY

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

Oesophageal cancer

(2017) Elizabeth C. Smyth et al.   Nature Reviews Disease Primers

Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial–mesenchymal transition in non-small cell lung cancer cells

(2016) Ching-Hao Li et al.   ARCHIVES OF TOXICOLOGY

Informing etiologic research priorities for squamous cell esophageal cancer in Africa: A review of setting-specific exposures to known and putative risk factors

(2016) V.A. McCormack et al.   INTERNATIONAL JOURNAL OF CANCER

Salidroside ameliorates arthritis-induced brain cognition deficits by regulating Rho/ROCK/NF-κB pathway

(2016) Lingpeng Zhu et al.   NEUROPHARMACOLOGY

Regulation of CXCR4/AKT-signaling-induced cell invasion and tumor metastasis by RhoA, Rac-1, and Cdc42 in human esophageal cancer

(2015) Jing Guo et al.   TUMOR BIOLOGY

Actin Cytoskeleton Regulation of Epithelial Mesenchymal Transition in Metastatic Cancer Cells

(2015) Jay Shankar et al.   PLoS One

Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration

(2010) Margaret L. Gardel et al.   Annual Review of Cell and Developmental Biology

Epidermal Growth Factor Stimulates Human Trophoblast Cell Migration through Rho A and Rho C Activation

(2010) Jian Han et al.   ENDOCRINOLOGY

EMT, the cytoskeleton, and cancer cell invasion

(2009) Mahmut Yilmaz et al.   CANCER AND METASTASIS REVIEWS

Aryl-hydrocarbon receptor-dependent alteration of FAK/RhoA in the inhibition of HUVEC motility by 3-methylcholanthrene

(2009) Chih-Cheng Chang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES