Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes

A Revised Mechanism for the Activation of Complement C3 to C3b

(2014) Elizabeth Rodriguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct localization of the complement C5b-9 complex on Gram-positive bacteria

(2013) Evelien T. M. Berends et al.   CELLULAR MICROBIOLOGY

Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex

(2011) Nick S Laursen et al.   EMBO JOURNAL

Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family

(2011) Brandon L. Garcia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Self-association and domain rearrangements between complement C3 and C3u provide insight into the activation mechanism of C3

(2010) Keying Li et al.   BIOCHEMICAL JOURNAL

Functional basis for complement evasion by staphylococcal superantigen-like 7

(2010) Jovanka Bestebroer et al.   CELLULAR MICROBIOLOGY

Convertase Inhibitory Properties of Staphylococcal Extracellular Complement-binding Protein

(2010) Ilse Jongerius et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Systemic Pro-Inflammatory Response in Sepsis

(2010) Hanna Katrien de Jong et al.   Journal of Innate Immunity

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus

(2010) Nick S. Laursen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The internal thioester and the covalent binding properties of the complement proteins C3 and C4

(2010) S. K. Alex Law et al.   PROTEIN SCIENCE

Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation

(2009) S. Heinen et al.   BLOOD

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

(2009) Suzan H M Rooijakkers et al.   NATURE IMMUNOLOGY

Structure of and influence of a tick complement inhibitor on human complement component 5

(2008) Folmer Fredslund et al.   NATURE IMMUNOLOGY

FDA Report: Eculizumab (Soliris(R)) for the Treatment of Patients with Paroxysmal Nocturnal Hemoglobinuria

(2008) A. Dmytrijuk et al.   ONCOLOGIST