Article
Environmental Sciences
Joanna M. Goncalves, Vania Serrao Sousa, Margarida Ribau Teixeira, Maria Joao Bebianno
Summary: This study examined the effects of polystyrene nanoplastics on marine mussels and found that nanoplastics induce genotoxicity and oxidative damage in these organisms, overwhelming antioxidant enzymes and causing tissue-dependent toxicity over time. The results suggest that mussel tissues are incapable of coping with the adverse effects of nanoplastics.
Article
Environmental Sciences
Tugce Kalefetoglu Macar, Oksal Macar, Kultigin Cavusoglu, Emine Yalcin, Kursad Yapar
Summary: The present study evaluated the mitigative ability of turmeric against nickel chloride-related toxicity in the roots of Allium cepa. Turmeric showed remarkable protection potential against NiCl2 and improved various parameters in Allium cepa.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Eryka Costa Almeida, Larissa Souza Passos, Carlos Eduardo Delfino Vieira, Raphael Danna Acayaba, Cassiana Carolina Montagner, Ernani Pinto, Claudia Bueno dos Reis Martinez, Ana Lucia Fonseca
Summary: Female juveniles of the Neotropical fish Astyanax altiparanae exposed to Imidacloprid showed oxidative damage in different organs, neurotoxic effects in the muscle, and genotoxicity, indicating potential health risks in environmentally relevant concentrations.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Xiaorui Shi, Xinan Wang, Rong Huang, Chu Tang, Chong Hu, Pengbo Ning, Fu Wang
Summary: Micro- and nano-sized plastics (MPs and NPs) have become a global environmental concern. This study evaluated the cytotoxicity and genotoxicity of polystyrene (PS) MPs and NPs on human lung cells. The results showed that nano-level PS caused more serious cytotoxicity and genotoxicity compared to micro-level PS. Additionally, surface-modified PS-NPs were found to have stronger cell viability inhibitory ability and induced more micronuclei.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Galina N. Chelomina, Sergey P. Kukla, Viktor P. Chelomin, Pham N. Doanh
Summary: Parasite infection can lead to DNA damage, potentially involving oxidative stress and cancer development; these research findings are important for understanding the pathogenesis mechanisms of parasitic diseases.
Article
Environmental Sciences
Vilena Kasuba, Blanka Tariba Lovakovic, Ana Lucic Vrdoljak, Anja Katic, Nevenka Kopjar, Vedran Micek, Mirta Milic, Alica Pizent, Davor Zeljezic, Suzana Zunec
Summary: This study evaluated the toxicity of alpha-cypermethrin in rats and found that it affected the weight of the kidney, liver, and brain, as well as causing brain and DNA damage. The results indicate the potential hazards posed by exposure to even low doses of alpha-cypermethrin.
Review
Environmental Sciences
Ivana Durovcova, Stanislav Kyzek, Jana Fabova, Jana Makukova, Eliska Galova, Andrea Sevcovicova
Summary: This review aims to summarize the genotoxic effects of BPA on organisms across all taxa. BPA can induce DNA damage through multiple mechanisms and has adverse effects on organisms in various ecosystems.
ENVIRONMENTAL POLLUTION
(2022)
Article
Multidisciplinary Sciences
Emine Yalcin, Kultigin Cavusoglu
Summary: This study investigated the toxic effects of potassium bromate on Allium cepa L. and tested the reducing effects of grape seed extract (GSE). The results showed that potassium bromate exposure caused decreases in physiological parameters and abnormalities in cell genetic indicators, disrupting the antioxidant/oxidant balance. GSE administration reduced the toxic effects of potassium bromate and improved the examined parameters.
SCIENTIFIC REPORTS
(2022)
Review
Environmental Sciences
Rupa Rani, Abhidha Kela, Geeta Dhaniya, Kamini Arya, Amit K. Tripathi, Rajesh Ahirwar
Summary: Specific miRNAs have been identified as early warning biomarkers for health effects associated with exposure to PAHs in exposed populations, and they can serve as indicators of early health effects in response to chronic environmental exposure to PAHs.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Joelle Auclair, Patrice Turcotte, Christian Gagnon, Caroline Peyrot, Kevin James Wilkinson, Francois Gagne
Summary: The study examined the sub-lethal toxicity of low concentrations of selected nanoparticles alone and in mixtures in juvenile trout. The results showed that the nanoparticles were bioavailable for fish, with different levels of toxicity for different nanoparticles and antagonistic effects in the mixtures. In conclusion, the bioavailability and toxicity of these nanoparticles are influenced by mixtures of nanoparticles, which is likely to occur in contaminated environments.
Review
Biotechnology & Applied Microbiology
Emilio Di Ianni, Nicklas Raun Jacobsen, Ulla Birgitte Vogel, Peter Moller
Summary: This systematic review evaluates the contribution of primary and secondary genotoxicity caused by carbon black exposure. It suggests that carbon black has a weak genotoxic effect, mainly through a primary genotoxic mechanism mediated by oxidative stress, rather than inflammation-driven secondary genotoxicity.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Zhangjian Chen, Jiaqi Shi, Yi Zhang, Shuo Han, Jiahe Zhang, Guang Jia
Summary: The genotoxic effects and underlying mechanisms of titanium dioxide nanoparticles (TiO2 NPs) on human bronchial epithelial cells (BEAS-2B) were investigated in this study. TiO2 NPs were found to induce cytotoxicity, oxidative stress, and DNA oxidative damage, with DNA oxidative damage being a more sensitive indicator for detecting the genotoxicity of TiO2 NPs.
Article
Biochemistry & Molecular Biology
Muhammed Atamanalp, Hasan Turkez, Asli cilingir Yeltekin, Fatma Betuel Ozgeris, Arzu Ucar, Ozge caglar, Veysel Parlak, Sena Oner, Gonca Alak
Summary: The compound acrylamide (AA) is widely used in industries such as paper, dyes, and plastics, but its water solubility suggests it could pose environmental problems. AA has been found to be neurotoxic, immunotoxic, reproductive toxic, and carcinogenic in animals. This study investigated the potential of boron compounds, such as borax (BX), to ameliorate AA-induced toxicities in rainbow trout. The results showed that AA exposure led to oxidative stress and DNA damage in both blood and liver tissues of the fish. However, co-exposure of BX with AA also elicited oxidative stress and cell death. Overall, BX was suggested as a useful and effective natural agent for preventing and treating AA toxicity in fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Environmental Sciences
Silvana Arias, Veronica Estrada, Isabel C. Ortiz, Francisco J. Molina, John R. Agudelo
Summary: This study investigated the biological response of soluble organic fraction (SOF) and water-soluble fraction (WSF) extracted from particles emitted by an automotive diesel engine. The results showed that SOF had no cytotoxic activity, but different fuel blends had varying effects on genotoxicity and oxidative DNA damage. WSF did not show any ecotoxicity, but certain fuel blends increased the toxicity of polycyclic aromatic hydrocarbons.
ENVIRONMENTAL POLLUTION
(2022)
Article
Biochemistry & Molecular Biology
Islam El-Garawani, Sobhy Hassab El-Nabi, Ahmed El Kattan, Azza Sallam, Sabha Elballat, Shaimaa Abou-Ghanima, Islam H. El Azab, Hesham R. El-Seedi, Shaden A. M. Khalifa, Sawsan El-Shamy
Summary: The study demonstrated that Arabic gum has a protective effect against oxidative stress and genotoxicity induced by a radiographic contrast medium. The active metabolites in Arabic gum were identified as key contributors to this protective role.