Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling‐mediated TRAF6 and c‐Src recruitment and NF‐κB, MAPK and Akt pathways

Development of 3-mercaptopropyltrimethoxysilane (MPTS)-modified bone marrow mononuclear cell membrane chromatography for screening anti-osteoporosis components from Scutellariae Radix

(2020) Yanqiu Gu et al.   Acta Pharmaceutica Sinica B

Reversal of Osteoporotic Activity by Endothelial Cell-Secreted Bone Targeting and Biocompatible Exosomes

(2019) Hongyuan Song et al.   NANO LETTERS

Nanotopographical Cues Mediate Osteogenesis of Stem Cells on Virus Substrates through BMP-2 Intermediate

(2019) Kamolrat Metavarayuth et al.   NANO LETTERS

Comprehensive two-dimensional APTES-decorated MCF7-cell membrane chromatographic system for characterizing potential anti-breast-cancer components from Yuanhu–Baizhi herbal medicine pair

(2018) Xiao-Yu Wang et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

A Matrine Derivative M54 Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss by Targeting Ribosomal Protein S5

(2018) Zhi Xin et al.   Frontiers in Pharmacology

18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways

(2018) Xiao Chen et al.   Frontiers in Pharmacology

Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis

(2017) Xiao Chen et al.   FASEB JOURNAL

Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis

(2017) Xiao Chen et al.   Cell Death & Disease

Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway

(2017) Mengrui Wu et al.   Nature Communications

On-line comprehensive two-dimensional HepG2 cell membrane chromatographic analysis system for charactering anti-hepatoma components from rat serum after oral administration of Radix scutellariae : A strategy for rapid screening active compounds in vivo

(2016) Dan Jia et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Postmenopausal osteoporosis

(2016) Richard Eastell et al.   Nature Reviews Disease Primers

Enhanced TRAIL-mediated apoptosis in prostate cancer cells by the bioactive compounds neobavaisoflavone and psoralidin isolated from Psoralea corylifolia

(2014) Ewelina Szliszka et al.   Pharmacological Reports

Physiological Functions of Osteoblast Lineage and T Cell-Derived RANKL in Bone Homeostasis

(2013) Toshio Fumoto et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Neobavaisoflavone stimulates osteogenesis via p38-mediated up-regulation of transcription factors and osteoid genes expression in MC3T3-E1 cells

(2012) Ming-Jaw Don et al.   PHYTOMEDICINE

Inhibition of Inflammatory Mediators by Neobavaisoflavone in Activated RAW264.7 Macrophages

(2011) Ewelina Szliszka et al.   MOLECULES

Implication of the calcium sensing receptor and the Phosphoinositide 3-kinase/Akt pathway in the extracellular calcium-mediated migration of RAW 264.7 osteoclast precursor cells

(2010) Cédric Boudot et al.   BONE

Characterization of the mouse tartrate-resistant acid phosphatase (trap) gene promoter

(2010) S.V. Reddy et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay

(2010) Guodong Xiao et al.   JOURNAL OF CHROMATOGRAPHY A

Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis

(2009) Steven R. Cummings et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of Buguzhi (Psoralea corylifolia fruit) extract on bone formation

(2009) R. W. K. Wong et al.   PHYTOTHERAPY RESEARCH

Osteoporosis and Inflammation

(2008) Gregory R. Mundy   NUTRITION REVIEWS

TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL

(2008) Matthew C. Walsh et al.   PLoS One

Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis

(2008) Y. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Tyrosine Kinase Activity of c-Src Regulates Actin Dynamics and Organization of Podosomes in Osteoclasts

(2007) Olivier Destaing et al.   MOLECULAR BIOLOGY OF THE CELL