Runx2 Regulates Mouse Tooth Root Development Via Activation of WNT Inhibitor NOTUM

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Notum attenuates Wnt/β–catenin signaling to promote tracheal cartilage patterning

(2018) Bradley Gerhardt et al.   DEVELOPMENTAL BIOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Ablation of Runx2 in Ameloblasts Suppresses Enamel Maturation in Tooth Development

(2018) Qing Chu et al.   Scientific Reports

Runx2 regulates cranial suture closure by inducing hedgehog, Fgf, Wnt, and Pthlh signaling pathway gene expression in suture mesenchymal cells

(2018) Xin Qin et al.   HUMAN MOLECULAR GENETICS

Autocrine regulation of mesenchymal progenitor cell fates orchestrates tooth eruption

(2018) Akira Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dentin Dysplasia in Notum Knockout Mice

(2016) P. Vogel et al.   VETERINARY PATHOLOGY

Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation

(2016) Wanida Ono et al.   Nature Communications

Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation

(2015) Xinjun Zhang et al.   DEVELOPMENTAL CELL

Notum deacylates Wnt proteins to suppress signalling activity

(2015) Satoshi Kakugawa et al.   NATURE

The suture provides a niche for mesenchymal stem cells of craniofacial bones

(2015) Hu Zhao et al.   NATURE CELL BIOLOGY

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor

(2014) Hu Zhao et al.   Cell Stem Cell

WNT7B Promotes Bone Formation in part through mTORC1

(2014) Jianquan Chen et al.   PLoS Genetics

The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer

(2013) Martin W. Berchtold et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Disruption of Wnt/β-catenin Signaling in Odontoblasts and Cementoblasts Arrests Tooth Root Development in Postnatal Mouse Teeth

(2013) Ran Zhang et al.   International Journal of Biological Sciences

An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice

(2013) Takeshi Takarada et al.   JOURNAL OF BONE AND MINERAL RESEARCH

β-catenin is Required in Odontoblasts for Tooth Root Formation

(2013) T.H. Kim et al.   JOURNAL OF DENTAL RESEARCH

Excessive Wnt/β-catenin signaling disturbs tooth-root formation

(2012) C. H. Bae et al.   JOURNAL OF PERIODONTAL RESEARCH

Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation

(2011) Tak-Heun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Regulation of bone development and extracellular matrix protein genes by RUNX2

(2009) Toshihisa Komori   CELL AND TISSUE RESEARCH

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification

(2009) Athanasia Spandidos et al.   NUCLEIC ACIDS RESEARCH