Environmental Circadian Disruption Increases Stroke Severity and Dysregulates Immune Response

A reductionist, in vitro model of environmental circadian disruption demonstrates SCN-independent and tissue-specific dysregulation of inflammatory responses

(2019) Adam Stowie et al.   PLoS One

Stroke infarct volume estimation in fixed tissue: Comparison of diffusion kurtosis imaging to diffusion weighted imaging and histology in a rodent MCAO model

(2018) Vibeke Bay et al.   PLoS One

Stroke-induced immunosuppression and poststroke infection

(2018) Kaibin Shi et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Misalignment with the external light environment drives metabolic and cardiac dysfunction

(2017) Alexander C. West et al.   Nature Communications

Neuroinflammatory biomarkers: From stroke diagnosis and prognosis to therapy

(2016) Alba Simats et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sex Differences in the Impact of Shift Work Schedules on Pathological Outcomes in an Animal Model of Ischemic Stroke

(2016) David J. Earnest et al.   ENDOCRINOLOGY

Chronic photoperiod disruption does not increase vulnerability to focal cerebral ischemia in young normotensive rats

(2016) Ku Mastura Ku Mohd Noor et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Simulated Night Shift Disrupts Circadian Rhythms of Immune Functions in Humans

(2016) Marc Cuesta et al.   JOURNAL OF IMMUNOLOGY

Circadian misalignment increases cardiovascular disease risk factors in humans

(2016) Christopher J. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipopolysaccharide exacerbates infarct size and results in worsened post-stroke behavioral outcomes

(2015) Danielle N. Doll et al.   Behavioral and Brain Functions

Impacts of tissue-type plasminogen activator (tPA) on neuronal survival

(2015) Arnaud Chevilley et al.   Frontiers in Cellular Neuroscience

Environmental Circadian Disruption Elevates the IL-6 Response to Lipopolysaccharide in Blood

(2013) Kandis L. Adams et al.   JOURNAL OF BIOLOGICAL RHYTHMS

A Circadian Clock Gene, Rev-erb , Modulates the Inflammatory Function of Macrophages through the Negative Regulation of Ccl2 Expression

(2013) S. Sato et al.   JOURNAL OF IMMUNOLOGY

Sleep Loss and the Inflammatory Response in Mice Under Chronic Environmental Circadian Disruption

(2013) Allison J. Brager et al.   PLoS One

TH17 Cell Differentiation Is Regulated by the Circadian Clock

(2013) X. Yu et al.   SCIENCE

Aging Differentially Affects the Re-entrainment Response of Central and Peripheral Circadian Oscillators

(2012) M. T. Sellix et al.   JOURNAL OF NEUROSCIENCE

Effects of chronic systemic treatment with peroxisome proliferator-activated receptor α activators on neuroinflammation induced by intracerebral injection of lipopolysaccharide in adult mice

(2011) Guangming Wang et al.   NEUROSCIENCE RESEARCH

Circadian Clocks in Mouse and Human CD4+ T Cells

(2011) Thomas Bollinger et al.   PLoS One

The nuclear receptor REV-ERB  mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines

(2011) J. E. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene expression results in lipopolysaccharide-stimulated monocytes depend significantly on the choice of reference genes.

(2010) Armin P. Piehler et al.   BMC IMMUNOLOGY

Dysregulation of Inflammatory Responses by Chronic Circadian Disruption

(2010) O. Castanon-Cervantes et al.   JOURNAL OF IMMUNOLOGY

Relation of Anti- to Pro-Inflammatory Cytokine Ratios with Acute Myocardial Infarction

(2010) Santanu Biswas et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Rotating Night Shift Work and the Risk of Ischemic Stroke

(2009) D. L. Brown et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

A Rapid and Transient Peripheral Inflammatory Response Precedes Brain Inflammation after Experimental Stroke

(2009) Katie Z Chapman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Does neuroinflammation fan the flame in neurodegenerative diseases?

(2009) Tamy C Frank-Cannon et al.   Molecular Neurodegeneration

A circadian clock in macrophages controls inflammatory immune responses

(2009) Maren Keller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adverse effects of chronic circadian desynchronization in animals in a “challenging” environment

(2008) Fabian Preuss et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Filamentous Middle Cerebral Artery Occlusion Causes Ischemic Damage to the Retina in Mice

(2008) Ernest C. Steele et al.   STROKE