Age-Specific Retinal and Cerebral Immunodetection of Amyloid-β Plaques and Oligomers in a Rodent Model of Alzheimer’s Disease

Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer’s disease

(2019) Xavier Hadoux et al.   Nature Communications

High performance plasma amyloid-β biomarkers for Alzheimer’s disease

(2018) Akinori Nakamura et al.   NATURE

The retina as a window to early dysfunctions of Alzheimer's disease following studies with a 5xFAD mouse model

(2018) Chiara Criscuolo et al.   NEUROBIOLOGY OF AGING

Ocular Manifestations of Alzheimer’s and Other Neurodegenerative Diseases: The Prospect of the Eye as a Tool for the Early Diagnosis of Alzheimer’s Disease

(2018) Pade Colligris et al.   Journal of Ophthalmology

Association of Preclinical Alzheimer Disease With Optical Coherence Tomographic Angiography Findings

(2018) Bliss Elizabeth O’Bryhim et al.   JAMA Ophthalmology

Amyloid β oligomers (AβOs) in Alzheimer’s disease

(2017) Barbara Mroczko et al.   JOURNAL OF NEURAL TRANSMISSION

Retinal biomarkers provide “insight” into cortical pharmacology and disease

(2017) Christine T.O. Nguyen et al.   PHARMACOLOGY & THERAPEUTICS

Oligomeric forms of amyloid-β protein in plasma as a potential blood-based biomarker for Alzheimer’s disease

(2017) Min Jeong Wang et al.   Alzheimers Research & Therapy

A Method for the Detection of Amyloid-β1-40, Amyloid-β1-42 and Amyloid-β Oligomers in Blood Using Magnetic Beads in Combination with Flow Cytometry and its Application in the Diagnostics of Alzheimer's Disease

(2017) Alexander Navarrete Santos et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's Disease and the Amyloid-β Peptide

(2017) M. Paul Murphy et al.   JOURNAL OF ALZHEIMERS DISEASE

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

The Eye As a Biomarker for Alzheimer's Disease

(2016) Jeremiah K. H. Lim et al.   Frontiers in Neuroscience

The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy

(2016) Urmi Sengupta et al.   EBioMedicine

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

(2015) Kirsten L. Viola et al.   ACTA NEUROPATHOLOGICA

Innovative diagnostic tools for early detection of Alzheimer's disease

(2015) Christoph Laske et al.   Alzheimers & Dementia

Melanopsin retinal ganglion cell loss in Alzheimer disease

(2015) Chiara La Morgia et al.   ANNALS OF NEUROLOGY

Dementia of the eye: the role of amyloid beta in retinal degeneration

(2015) J A Ratnayaka et al.   EYE

Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer’s disease immunotherapeutics

(2014) William F Goure et al.   Alzheimers Research & Therapy

Developing novel blood-based biomarkers for Alzheimer's disease

(2013) Heather M. Snyder et al.   Alzheimers & Dementia

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

(2013) Sylvain E. Lesné et al.   BRAIN

Pupil Response Biomarkers for Early Detection and Monitoring of Alzheimer's Disease

(2013) Shaun Frost et al.   Current Alzheimer Research

Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification

(2013) Devin M. Wolfe et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Retinal vascular biomarkers for early detection and monitoring of Alzheimer’s disease

(2013) S Frost et al.   Translational Psychiatry

Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease

(2012) James D. Doecke   ARCHIVES OF NEUROLOGY

Plasma amyloid-β oligomers level is a biomarker for Alzheimer’s disease diagnosis

(2012) L. Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Toxicity of Amyloid ß Oligomers

(2012) Li Na Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system

(2012) Lin Zheng et al.   Translational Neurodegeneration

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

Soluble Aβ oligomer production and toxicity

(2011) Megan E. Larson et al.   JOURNAL OF NEUROCHEMISTRY

Brain Oligomeric β-Amyloid but Not Total Amyloid Plaque Burden Correlates With Neuronal Loss and Astrocyte Inflammatory Response in Amyloid Precursor Protein/Tau Transgenic Mice

(2011) Bibiana DaRocha-Souto et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo

(2011) Tomohiro Umeda et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Amyloid oligomers: formation and toxicity of Aβ oligomers

(2010) Masafumi Sakono et al.   FEBS Journal

Endocytic pathways mediating oligomeric Abeta42 neurotoxicity

(2010) Chunjiang Yu et al.   Molecular Neurodegeneration

Neuropathology of Alzheimer's Disease

(2010) Daniel P. Perl   MOUNT SINAI JOURNAL OF MEDICINE

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

(2010) Maya Koronyo-Hamaoui et al.   NEUROIMAGE

Retinal nerve fiber layer structure abnormalities in early Alzheimer's disease: Evidence in optical coherence tomography

(2010) Yan Lu et al.   NEUROSCIENCE LETTERS

The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?

(2010) Kerensa Broersen et al.   Alzheimers Research & Therapy

Amyloid-Peptide Vaccinations Reduce β-Amyloid Plaques but Exacerbate Vascular Deposition and Inflammation in the Retina of Alzheimer’s Transgenic Mice

(2009) Bingqian Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

A Specific Enzyme-Linked Immunosorbent Assay for Measuring β-Amyloid Protein Oligomers in Human Plasma and Brain Tissue of Patients With Alzheimer Disease

(2009) Weiming Xia et al.   ARCHIVES OF NEUROLOGY

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer’s disease

(2009) R. Michael Dutescu et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

An Overview of APP Processing Enzymes and Products

(2009) Vivian W. Chow et al.   NEUROMOLECULAR MEDICINE

Oxidative stress induces macroautophagy of amyloid β-protein and ensuing apoptosis

(2008) Lin Zheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY