Multifunctional Superparamagnetic Iron Oxide Nanoparticles Conjugated with Aβ Oligomer-Specific scFv Antibody and Class A Scavenger Receptor Activator Show Early Diagnostic Potentials for Alzheimer’s Disease

Aβ oligomers: role at the synapse

(2019) Daniela Puzzo   Aging-US

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Alzheimerʼs disease neuroimaging

(2018) Jennifer L. Whitwell   CURRENT OPINION IN NEUROLOGY

Alzheimer’s Disease, Oligomers, and Inflammation

(2018) Gianluigi Forloni et al.   JOURNAL OF ALZHEIMERS DISEASE

The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

(2018) Erika N. Cline et al.   JOURNAL OF ALZHEIMERS DISEASE

Crosstalk between endoplasmic reticulum stress and brain inflammation in Alzheimer's disease

(2018) Luis E. Santos et al.   NEUROPHARMACOLOGY

Amyloid toxicity in Alzheimer’s disease

(2018) Allison B. Reiss et al.   REVIEWS IN THE NEUROSCIENCES

Alzheimer’s disease

(2018) Richard Hodson   NATURE

An age-old story of dementia

(2018) Liam Drew   NATURE

Alzheimer’s disease is getting easier to spot

(2018) Elie Dolgin   NATURE

ScFv-conjugated superparamagnetic iron oxide nanoparticles for MRI-based diagnosis in transgenic mouse models of Parkinson’s and Huntington’s diseases

(2018) Xiao-ge Liu et al.   BRAIN RESEARCH

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Recent Progress in Alzheimer’s Disease Research, Part 3: Diagnosis and Treatment

(2017) Francis T. Hane et al.   JOURNAL OF ALZHEIMERS DISEASE

Microglia in Alzheimer’s disease

(2017) David V. Hansen et al.   JOURNAL OF CELL BIOLOGY

Microglia in Alzheimer’s disease

(2017) Heela Sarlus et al.   JOURNAL OF CLINICAL INVESTIGATION

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Exceedingly small iron oxide nanoparticles as positive MRI contrast agents

(2017) He Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

(2015) Kirsten L. Viola et al.   ACTA NEUROPATHOLOGICA

Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease

(2014) Kirsten L. Viola et al.   Nature Nanotechnology

Activated Scavenger Receptor A Promotes Glial Internalization of Aβ

(2014) He Zhang et al.   PLoS One

Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI

(2013) Jon B. Toledo et al.   ACTA NEUROPATHOLOGICA

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hybrid magnetic nanostructures (MNS) for magnetic resonance imaging applications

(2011) Mrinmoy De et al.   ADVANCED DRUG DELIVERY REVIEWS

Conformation-dependent scFv antibodies specifically recognize the oligomers assembled from various amyloids and show colocalization of amyloid fibrils with oligomers in patients with amyloidoses

(2011) Xi Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease

(2011) M. T. Fodero-Tavoletti et al.   BRAIN

Measurement of Aβ1-42 in cerebrospinal fluid is influenced by matrix effects

(2011) J. Randall Slemmon et al.   JOURNAL OF NEUROCHEMISTRY

Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease

(2010) C. R. Jack et al.   BRAIN

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

Conformation-dependent single-chain variable fragment antibodies specifically recognize beta-amyloid oligomers

(2009) Xiao-ping Wang et al.   FEBS LETTERS

Multimodal techniques for diagnosis and prognosis of Alzheimer's disease

(2009) Richard J. Perrin et al.   NATURE

β-Amyloid impairs axonal BDNF retrograde trafficking

(2009) Wayne W. Poon et al.   NEUROBIOLOGY OF AGING

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

(2009) G. Pigino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA