Lactoferrin as Protective Natural Barrier of Respiratory and Intestinal Mucosa against Coronavirus Infection and Inflammation

Compounds with therapeutic potential against novel respiratory 2019 coronavirus

(2020) Miguel Angel Martinez   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure analysis of the receptor binding of 2019-nCoV

(2020) Yun Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diarrhoea may be underestimated: a missing link in 2019 novel coronavirus

(2020) Weicheng Liang et al.   GUT

Novel Anticoagulant Peptide from Lactoferrin Binding Thrombin at the Active Site and Exosite-I

(2020) Shiqi Xu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Retinol and vitamin A metabolites accumulate through RBP4 and STRA6 changes in a psoriasis murine model

(2020) Hai-meng Wang et al.   Nutrition & Metabolism

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies

(2020) Syed Faraz Ahmed et al.   Viruses-Basel

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

(2020) Xiaolong Tian et al.   Emerging Microbes & Infections

Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review

(2020) Junxiong Pang et al.   Journal of Clinical Medicine

Digestive Symptoms in COVID-19 Patients With Mild Disease Severity

(2020) Chaoqun Han et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Updated Approaches against SARS-CoV-2

(2020) Haiou Li et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses

(2020) Furong Qi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion

(2020) Xinling Wang et al.   Cellular & Molecular Immunology

Coronaviruses and the cardiovascular system: acute and long-term implications

(2020) Tian-Yuan Xiong et al.   EUROPEAN HEART JOURNAL

COVID-19 in gastroenterology: a clinical perspective

(2020) John Ong et al.   GUT

Clinical characteristics of 194 cases of COVID-19 in Huanggang and Taian, China

(2020) Hong Zhang et al.   INFECTION

Expression of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in the Gut of Patients With IBD

(2020) Juan F Burgueño et al.   INFLAMMATORY BOWEL DISEASES

High IL‐6/IFN‐γ ratio could be associated with severe disease in COVID‐19 patients

(2020) Francisco Alejandro Lagunas‐Rangel et al.   JOURNAL OF MEDICAL VIROLOGY

SARS-CoV-2 and viral sepsis: observations and hypotheses

(2020) Hui Li et al.   LANCET

Viral Hepatitis and Iron Dysregulation: Molecular Pathways and the Role of Lactoferrin

(2020) Romina Mancinelli et al.   MOLECULES

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Prolonged presence of SARS-CoV-2 viral RNA in faecal samples

(2020) Yongjian Wu et al.   Lancet Gastroenterology & Hepatology

Specific ACE2 expression in small intestinal enterocytes may cause gastrointestinal symptoms and injury after 2019-nCoV infection

(2020) Hui Zhang et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Direct endothelial damage and vasculitis due to SARS‐CoV‐2 in small bowel submucosa of COVID‐19 patient with diarrhea

(2020) Sergio Carnevale et al.   JOURNAL OF MEDICAL VIROLOGY

Gut microbiota and Covid-19- possible link and implications

(2020) Debojyoti Dhar et al.   VIRUS RESEARCH

Aerosolized Bovine Lactoferrin Counteracts Infection, Inflammation and Iron Dysbalance in A Cystic Fibrosis Mouse Model of Pseudomonas aeruginosa Chronic Lung Infection

(2019) Antimo Cutone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Lactoferrin in Neonates and Infants: An Update

(2018) Alberto Dall'Agnola et al.   AMERICAN JOURNAL OF PERINATOLOGY

Lactoferrin is a natural inhibitor of plasminogen activation

(2018) Alexander Zwirzitz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy of Lactoferrin Oral Administration in the Treatment of Anemia and Anemia of Inflammation in Pregnant and Non-pregnant Women: An Interventional Study

(2018) Maria Stefania Lepanto et al.   Frontiers in Immunology

The role of the lung microbiota and the gut-lung axis in respiratory infectious diseases

(2018) Alexia Dumas et al.   CELLULAR MICROBIOLOGY

Antibacterial activity of lysozyme-binding proteins from chicken egg white

(2018) Youji Shimazaki et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Lactoferrin: A Natural Glycoprotein Involved in Iron and Inflammatory Homeostasis

(2017) Luigi Rosa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lactoferrin Efficiently Counteracts the Inflammation-Induced Changes of the Iron Homeostasis System in Macrophages

(2017) Antimo Cutone et al.   Frontiers in Immunology

Lactoferrin in a Context of Inflammation-Induced Pathology

(2017) Marian L. Kruzel et al.   Frontiers in Immunology

Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses

(2016) Shuo Su et al.   TRENDS IN MICROBIOLOGY

The microbiome and critical illness

(2016) Robert P Dickson   Lancet Respiratory Medicine

Structure, Function, and Evolution of Coronavirus Spike Proteins

(2016) Fang Li   Annual Review of Virology

Aerosol Performance and Stability of Liposomes Containing Ciprofloxacin Nanocrystals

(2015) David Cipolla et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Delivery strategies for sustained drug release in the lungs

(2014) Cristina Loira-Pastoriza et al.   ADVANCED DRUG DELIVERY REVIEWS

Lactoferrin differently modulates the inflammatory response in epithelial models mimicking human inflammatory and infectious diseases

(2014) Alessandra Frioni et al.   BIOMETALS

Safety and efficacy of lactoferrin versus ferrous sulphate in curing iron deficiency and iron deficiency anaemia in hereditary thrombophilia pregnant women: an interventional study

(2014) Rosalba Paesano et al.   BIOMETALS

Lactoferrin prevents LPS-induced decrease of the iron exporter ferroportin in human monocytes/macrophages

(2014) Antimo Cutone et al.   BIOMETALS

Mannosylated solid lipid nanoparticles for lung-targeted delivery of Paclitaxel

(2014) Piyush Kumar Sahu et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Lactoferrin for prevention of common viral infections

(2014) Hiroyuki Wakabayashi et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Distinct patterns of hepcidin and iron regulation during HIV-1, HBV, and HCV infections

(2014) A. E. Armitage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stability during in vitro digestion of lactoferrin-loaded liposomes prepared from milk fat globule membrane-derived phospholipids

(2013) Weilin Liu et al.   JOURNAL OF DAIRY SCIENCE

Systemic Iron Homeostasis

(2013) Tomas Ganz   PHYSIOLOGICAL REVIEWS

Biochemical and molecular impacts of lactoferrin on small intestinal growth and development during early life1This article is part of a Special Issue entitled Lactoferrin and has undergone the Journal's usual peer review process.

(2012) Yalin Liao et al.   Biochemistry and Cell Biology

2-Hydroxypropyl-β-cyclodextrin-modified SLN of paclitaxel for overcoming p-glycoprotein function in multidrug-resistant breast cancer cells

(2012) Jong-Suep Baek et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

(2011) I. Glowacka et al.   JOURNAL OF VIROLOGY

Antiviral Properties of Lactoferrin—A Natural Immunity Molecule

(2011) Francesca Berlutti et al.   MOLECULES

Inhibition of SARS Pseudovirus Cell Entry by Lactoferrin Binding to Heparan Sulfate Proteoglycans

(2011) Jianshe Lang et al.   PLoS One

Lactoferrin as a Natural Immune Modulator

(2009) Jeffrey Actor et al.   CURRENT PHARMACEUTICAL DESIGN

Virus Movements on the Plasma Membrane Support Infection and Transmission between Cells

(2009) Christoph J. Burckhardt et al.   PLoS Pathogens

The N1 Domain of Human Lactoferrin Is Required for Internalization by Caco-2 Cells and Targeting to the Nucleus†

(2008) Yasushi A. Suzuki et al.   BIOCHEMISTRY

Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein

(2008) Yu-Jung Chien et al.   VIROLOGY