Glucagon-Like Peptide-1 Receptor Agonist Prevented the Progression of Hepatocellular Carcinoma in a Mouse Model of Nonalcoholic Steatohepatitis

Glucagon‑like peptide‑1 modulates RAW264.7 macrophage polarization by interfering with the JNK/STAT3 signaling pathway

(2019) Shan Wan et al.   Experimental and Therapeutic Medicine

Liraglutide protects against inflammatory stress in non-alcoholic fatty liver by modulating Kupffer cells M2 polarization via cAMP-PKA-STAT3 signaling pathway

(2019) Zhi Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in Hepatocellular Carcinoma

(2019) Teruo Jojima et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Apoptosis and non-alcoholic fatty liver diseases

(2018) Tatsuo Kanda et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Glucagon-Like Peptide-1 Increases Beta Cell Regeneration by Promoting Alpha- to Beta-Cell Transdifferentiation

(2018) Young-Sun Lee et al.   DIABETES

Global Perspectives on Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis

(2018) Zobair Younossi et al.   HEPATOLOGY

Effects of a DPP4 Inhibitor on Progression of NASH-related HCC and the p62/ Keap1/Nrf2-Pentose Phosphate Pathway in a Mouse Model

(2018) Takumi Kawaguchi et al.   Liver Cancer

Characteristics of non-alcoholic steatohepatitis among lean patients in Japan: Not uncommon and not always benign

(2018) Maki Tobari et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

New trends on obesity and NAFLD in Asia

(2017) Jian-Gao Fan et al.   JOURNAL OF HEPATOLOGY

The anti-diabetic drug exenatide, a glucagon-like peptide-1 receptor agonist, counteracts hepatocarcinogenesis through cAMP–PKA–EGFR–STAT3 axis

(2017) M Zhou et al.   ONCOGENE

Liraglutide improves liver microvascular dysfunction in cirrhosis: Evidence from translational studies

(2017) Fernanda Cristina de Mesquita et al.   Scientific Reports

The Cardiovascular Biology of Glucagon-like Peptide-1

(2016) Daniel J. Drucker   Cell Metabolism

Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study

(2016) Matthew James Armstrong et al.   LANCET

GLP-1 contributes to increases in PGC-1α expression by downregulating miR-23a to reduce apoptosis

(2015) Chi Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nonalcoholic Steatohepatitis (NASH) Is Associated with a Decline in Pancreatic Beta Cell (β-Cell) Function

(2015) Mohammad S. Siddiqui et al.   DIGESTIVE DISEASES AND SCIENCES

Glucagon-like peptide-1 receptor agonists inhibit hepatic stellate cell activation by blocking the p38 MAPK signaling pathway

(2015) L.K. Wu et al.   GENETICS AND MOLECULAR RESEARCH

Pilot study of liraglutide effects in non-alcoholic steatohepatitis and non-alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN-J)

(2014) Yuichiro Eguchi et al.   HEPATOLOGY RESEARCH

Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults

(2014) Krishnan Bhaskaran et al.   LANCET

AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer

(2013) D. G. Hardie   DIABETES

Advanced glycation endproducts induce fibrogenic activity in nonalcoholic steatohepatitis by modulating TNF-α-converting enzyme activity in mice

(2013) Joy X. Jiang et al.   HEPATOLOGY

A murine model for non-alcoholic steatohepatitis showing evidence of association between diabetes and hepatocellular carcinoma

(2013) Masato Fujii et al.   Medical Molecular Morphology

Update on incretin hormones

(2012) Liza K. Phillips et al.   Annals of the New York Academy of Sciences

An overview of the pharmacokinetics, efficacy and safety of liraglutide

(2012) Bruce Bode   DIABETES RESEARCH AND CLINICAL PRACTICE

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet

(2011) Jamie E. Mells et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The peptide-hormone glucagon-like peptide-1 activates cAMP and inhibits growth of breast cancer cells

(2011) Hagai Ligumsky et al.   BREAST CANCER RESEARCH AND TREATMENT

Glucagon-Like Peptide-1 Receptor Activation Inhibits Growth and Augments Apoptosis in Murine CT26 Colon Cancer Cells

(2011) Jacqueline A. Koehler et al.   ENDOCRINOLOGY

Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis

(2011) Gianluca Svegliati-Baroni et al.   LIVER INTERNATIONAL

Glutamine Synthetase Immunostaining Correlates with Pathologic Features of Hepatocellular Carcinoma and Better Survival after Radiofrequency Thermal Ablation

(2010) B. Dal Bello et al.   CLINICAL CANCER RESEARCH

Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

(2010) Nitika Arora Gupta et al.   HEPATOLOGY

Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection

(2010) Brad Q. Starley et al.   HEPATOLOGY

Liraglutide in clinical practice: dosing, safety and efficacy

(2010) G. E. Peterson et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

PKCδ Is Activated in a Dietary Model of Steatohepatitis and Regulates Endoplasmic Reticulum Stress and Cell Death

(2010) Michael W. Greene et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase

(2010) Shani Ben-Shlomo et al.   JOURNAL OF HEPATOLOGY

Exendin-4 Potentiates Insulinotropic Action Partly via Increasing β-Cell Proliferation and Neogenesis and Decreasing Apoptosis in Association With the Attenuation of Endoplasmic Reticulum Stress in Islets of Diabetic Rats

(2009) Dae Young Kwon et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES