Indoleamine 2,3-Dioxygenase 2 Deficiency Exacerbates Imiquimod-Induced Psoriasis-Like Skin Inflammation

Imiquimod-Induced Psoriasis in Mice Depends on the IL-17 Signaling of Keratinocytes

(2019) Sonja Moos et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis

(2018) Jason E. Hawkes et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling

(2018) Yasuko Yamamoto et al.   Scientific Reports

IL-17 for therapy

(2017) Florian C. Kurschus et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Kynurenic acid downregulates IL-17/1L-23 axis in vitro

(2017) Sanam Salimi Elizei et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Immune cells from patients with psoriasis are defective in inducing indoleamine 2,3-dioxygenase expression in response to inflammatory stimuli

(2016) M. Llamas-Velasco et al.   BRITISH JOURNAL OF DERMATOLOGY

IDO2 Modulates T Cell–Dependent Autoimmune Responses through a B Cell–Intrinsic Mechanism

(2016) Lauren M. F. Merlo et al.   JOURNAL OF IMMUNOLOGY

Characterisation of the Kynurenine Pathway in Skin-Derived Fibroblasts and Keratinocytes

(2015) Diba Sheipouri et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1

(2014) Georgios Pantouris et al.   AMINO ACIDS

IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation

(2014) Richard Metz et al.   INTERNATIONAL IMMUNOLOGY

IDO2 Is a Critical Mediator of Autoantibody Production and Inflammatory Pathogenesis in a Mouse Model of Autoimmune Arthritis

(2014) L. M. F. Merlo et al.   JOURNAL OF IMMUNOLOGY

The Aryl Hydrocarbon Receptor Meets Immunology: Friend or Foe? A Little of Both

(2014) Walker Julliard et al.   Frontiers in Immunology

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease

(2013) Amos A. Fatokun et al.   AMINO ACIDS

TLRs to cytokines: Mechanistic insights from the imiquimod mouse model of psoriasis

(2013) Barry Flutter et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Studies on Tissue and Cellular Distribution of Indoleamine 2,3-Dioxygenase 2

(2012) Masakazu Fukunaga et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

An Alternative Pathway of Imiquimod-Induced Psoriasis-Like Skin Inflammation in the Absence of Interleukin-17 Receptor A Signaling

(2012) Khalifa El Malki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts

(2011) Linnéa Asp et al.   Journal of Inflammation-London

1-l-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-d-methyltryptophan

(2010) Hajime J. Yuasa et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

Psoriasis: what we have learned from mouse models

(2010) Erwin F. Wagner et al.   Nature Reviews Rheumatology

Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases

(2009) Hajime J. Yuasa et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

(2009) L. van der Fits et al.   JOURNAL OF IMMUNOLOGY

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway

(2008) Helen J. Ball et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY