2-Ketoglutarate-Generated In Vitro Enzymatic Biosystem Facilitates Fe(II)/2-Ketoglutarate-Dependent Dioxygenase-Mediated C–H Bond Oxidation for (2s,3r,4s)-4-Hydroxyisoleucine Synthesis

Highly Regioselective and Stereoselective Hydroxylation of Free Amino Acids by a 2-Oxoglutarate-Dependent Dioxygenase from Kutzneria albida

(2019) Xiaoran Jing et al.   ACS Omega

Engineered disulfide bonds improve thermostability and activity of L‐isoleucine hydroxylase for efficient 4‐HIL production in Bacillus subtilis 168

(2019) Zhina Qiao et al.   ENGINEERING IN LIFE SCIENCES

Biocatalytic Oxidation Reactions: A Chemist's Perspective

(2018) JiaJia Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Promoter engineering of cascade biocatalysis for α-ketoglutaric acid production by coexpressing l-glutamate oxidase and catalase

(2018) Jing Wu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

High production of 4-hydroxyisoleucine in Corynebacterium glutamicum by multistep metabolic engineering

(2018) Chenglin Zhang et al.   METABOLIC ENGINEERING

Improvement of the Activity and Stability of Starch-Debranching Pullulanase from Bacillus naganoensis via Tailoring of the Active Sites Lining the Catalytic Pocket

(2018) Xinye Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

In vitro metabolic engineering for the production of α-ketoglutarate

(2017) Barbara Beer et al.   METABOLIC ENGINEERING

Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity

(2017) Peer Lukat et al.   Chemical Science

4-Hydroxyisoleucine: A Potential New Treatment for Type 2 Diabetes Mellitus

(2016) Mohammad Ishraq Zafar et al.   BIODRUGS

Recent Advances in C–H Functionalization

(2016) Huw M. L. Davies et al.   JOURNAL OF ORGANIC CHEMISTRY

Trends in applying C–H oxidation to the total synthesis of natural products

(2016) Yuanyou Qiu et al.   NATURAL PRODUCT REPORTS

Forward design of a complex enzyme cascade reaction

(2016) Christoph Hold et al.   Nature Communications

4-Hydroxyisoleucine production of recombinant Corynebacterium glutamicum ssp. lactofermentum under optimal corn steep liquor limitation

(2015) Feng Shi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Catalytic Mechanisms of Fe(II)- and 2-Oxoglutarate-dependent Oxygenases

(2015) Salette Martinez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reconstitution of TCA cycle with DAOCS to engineerEscherichia coliinto an efficient whole cell catalyst of penicillin G

(2015) Baixue Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-Enzymatic Synthesis of Optically Pure β-Hydroxy α-Amino Acids

(2014) Makoto Hibi et al.   ADVANCED SYNTHESIS & CATALYSIS

Enzymatic production of α-ketoglutaric acid from l-glutamic acid via l-glutamate oxidase

(2014) Panqing Niu et al.   JOURNAL OF BIOTECHNOLOGY

Refined Regio- and Stereoselective Hydroxylation of l-Pipecolic Acid by Protein Engineering of l-Proline cis-4-Hydroxylase Based on the X-ray Crystal Structure

(2014) Kento Koketsu et al.   ACS Synthetic Biology

Proline Availability Regulates Proline-4-Hydroxylase Synthesis and Substrate Uptake in Proline-Hydroxylating Recombinant Escherichia coli

(2013) Francesco Falcioni et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

One-step production of α-ketoglutaric acid from glutamic acid with an engineered l-amino acid deaminase from Proteus mirabilis

(2013) Long Liu et al.   JOURNAL OF BIOTECHNOLOGY

Bioconversion of l-glutamic acid to α-ketoglutaric acid by an immobilized whole-cell biocatalyst expressing l-amino acid deaminase from Proteus mirabilis

(2013) Gazi Sakir Hossain et al.   JOURNAL OF BIOTECHNOLOGY

Cell-Free Metabolic Engineering: Production of Chemicals by Minimized Reaction Cascades

(2012) Jan-Karl Guterl et al.   ChemSusChem

If CH Bonds Could Talk: Selective CH Bond Oxidation

(2011) Timothy Newhouse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization of Bacillus thuringiensis l-Isoleucine Dioxygenase for Production of Useful Amino Acids

(2011) Makoto Hibi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Inhibition of 2-oxoglutarate dependent oxygenases

(2011) Nathan R. Rose et al.   CHEMICAL SOCIETY REVIEWS

Metabolic engineering of Escherichia coli to produce (2S, 3R, 4S)-4-hydroxyisoleucine

(2010) Sergey V. Smirnov et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The high-throughput protein sample production platform of the Northeast Structural Genomics Consortium

(2010) Rong Xiao et al.   JOURNAL OF STRUCTURAL BIOLOGY

New strategy for the synthesis of N-aryl pyrroles: Cu-catalyzed C–N cross-coupling reaction of trans-4-hydroxy-l-proline with aryl halides

(2010) V. Prakash Reddy et al.   TETRAHEDRON LETTERS

Characterization of novel 2-oxoglutarate dependent dioxygenases converting l-proline to cis-4-hydroxy-l-proline

(2009) Ryotaro Hara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A novel l-isoleucine hydroxylating enzyme, l-isoleucine dioxygenase from Bacillus thuringiensis, produces (2S,3R,4S)-4-hydroxyisoleucine

(2009) Tomohiro Kodera et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Solubility of l-serine, l-threonine and l-isoleucine in aqueous aliphatic alcohol solutions

(2008) Luísa A. Ferreira et al.   FLUID PHASE EQUILIBRIA