Robust and Scalable Angiogenesis Assay of Perfused 3D Human iPSC-Derived Endothelium for Anti-Angiogenic Drug Screening

Lowering the increased intracellular pH of human‐induced pluripotent stem cell‐derived endothelial cells induces formation of mature Weibel‐Palade bodies

(2020) Gesa L. Tiemeier et al.   Stem Cells Translational Medicine

Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells

(2019) B. Yetkin-Arik et al.   Scientific Reports

Standardized and Scalable Assay to Study Perfused 3D Angiogenic Sprouting of iPSC-derived Endothelial Cells In Vitro

(2019) Vincent van Duinen et al.   Jove-Journal of Visualized Experiments

Consensus guidelines for the use and interpretation of angiogenesis assays

(2018) Patrycja Nowak-Sliwinska et al.   ANGIOGENESIS

Perfused 3D angiogenic sprouting in a high-throughput in vitro platform

(2018) V. van Duinen et al.   ANGIOGENESIS

Construction of continuous capillary networks stabilized by pericyte-like perivascular cells

(2018) Kyoko Yamamoto et al.   TISSUE ENGINEERING PART A

Three-dimensional biomimetic model to reconstitute sprouting lymphangiogenesis in vitro

(2016) Sudong Kim et al.   BIOMATERIALS

Complex Tissue and Disease Modeling using hiPSCs

(2016) Robert Passier et al.   Cell Stem Cell

Screening out irrelevant cell-based models of disease

(2016) Peter Horvath et al.   NATURE REVIEWS DRUG DISCOVERY

Drug Discovery Goes Three-Dimensional: Goodbye to Flat High-Throughput Screening?

(2015) Richard M. Eglen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Microfluidic 3D cell culture: from tools to tissue models

(2015) Vincent van Duinen et al.   CURRENT OPINION IN BIOTECHNOLOGY

A quantitative microfluidic angiogenesis screen for studying anti-angiogenic therapeutic drugs

(2015) Choong Kim et al.   LAB ON A CHIP

Engineering of a Biomimetic Pericyte-Covered 3D Microvascular Network

(2015) Jaerim Kim et al.   PLoS One

Optimizing design and fabrication of microfluidic devices for cell cultures: An effective approach to control cell microenvironment in three dimensions

(2014) G. Pagano et al.   Biomicrofluidics

Tissue-engineered microenvironment systems for modeling human vasculature

(2014) Anna Tourovskaia et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hematopoietic Stem Cell Cytokines and Fibroblast Growth factor-2 Stimulate Human Endothelial Cell-Pericyte Tube Co-Assembly in 3D Fibrin Matrices under Serum-Free Defined Conditions

(2014) Annie O. Smith et al.   PLoS One

Dll4-containing exosomes induce capillary sprout retraction in a 3D microenvironment

(2014) Soheila Sharghi-Namini et al.   Scientific Reports

Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis

(2013) Sandra Schoors et al.   Cell Metabolism

Engineers are from PDMS-land, Biologists are from Polystyrenia

(2012) Erwin Berthier et al.   LAB ON A CHIP

Angiogenic morphogenesis driven by dynamic and heterogeneous collective endothelial cell movement

(2011) S. Arima et al.   DEVELOPMENT

Phaseguides: a paradigm shift in microfluidic priming and emptying

(2011) Paul Vulto et al.   LAB ON A CHIP

Fluid forces control endothelial sprouting

(2011) J. W. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Globally optimal stitching of tiled 3D microscopic image acquisitions

(2009) S. Preibisch et al.   BIOINFORMATICS

Tipping the Balance: Robustness of Tip Cell Selection, Migration and Fusion in Angiogenesis

(2009) Katie Bentley et al.   PLoS Computational Biology