Influence of Herbal Medicines on HMGB1 Release, SARS-CoV-2 Viral Attachment, Acute Respiratory Failure, and Sepsis. A Literature Review

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV

(2020) Jiabao Xu et al.   Viruses-Basel

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Ebola virus glycoprotein GP1—host cell-surface HSPA5 binding site prediction

(2020) Abdo A. Elfiky   CELL STRESS & CHAPERONES

HMGB1 in nasal inflammatory diseases: a reappraisal 30 years after its discovery

(2020) Giorgio Ciprandi et al.   Expert Review of Clinical Immunology

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding

(2020) Yi Xu et al.   NATURE MEDICINE

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

(2020) Xiuyuan Ou et al.   Nature Communications

Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants

(2020) Muhammad Tahir ul Qamar et al.   Journal of Pharmaceutical Analysis

Abnormalities of peripheral blood system in patients with COVID-19 in Wenzhou, China

(2020) Suyu Sun et al.   CLINICA CHIMICA ACTA

COVID-19, SARS and MERS: are they closely related?

(2020) N. Petrosillo et al.   CLINICAL MICROBIOLOGY AND INFECTION

COVID-19 infection in kidney transplant recipients

(2020) Debasish Banerjee et al.   KIDNEY INTERNATIONAL

Suppressive Effects of Ginsenoside Rh1 on HMGB1-Mediated Septic Responses

(2019) Wonhwa Lee et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

(2019) Alexandra C. Walls et al.   CELL

Ginsenoside Rb1 inhibits proliferation and promotes apoptosis by regulating HMGB1 in uterine fibroid cells

(2019) Jianqiang Zhang et al.   Artificial Cells Nanomedicine and Biotechnology

Characteristics of flavonoids as potent MERS‐CoV 3C‐like protease inhibitors

(2019) Seri Jo et al.   Chemical Biology & Drug Design

Inhibition of SARS-CoV 3CL protease by flavonoids

(2019) Seri Jo et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Inula helenium and Grindelia squarrosa as a source of compounds with anti-inflammatory activity in human neutrophils and cultured human respiratory epithelium

(2019) Barbara Gierlikowska et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cucurbitacin E ameliorates lipopolysaccharide-evoked injury, inflammation and MUC5AC expression in bronchial epithelial cells by restraining the HMGB1-TLR4-NF-κB signaling

(2019) Jin Shang et al.   MOLECULAR IMMUNOLOGY

Plumbagin ameliorates hepatic ischemia-reperfusion injury in rats: Role of high mobility group box 1 in inflammation, oxidative stress and apoptosis

(2018) Aya M. Zaki et al.   BIOMEDICINE & PHARMACOTHERAPY

Effect of Tea Catechins on Influenza Infection and the Common Cold with a Focus on Epidemiological/Clinical Studies

(2018) Daisuke Furushima et al.   MOLECULES

Epidemiology and Immune Pathogenesis of Viral Sepsis

(2018) Gu-Lung Lin et al.   Frontiers in Immunology

In vitro studies on anti-inflammatory activities of kiwifruit peel extract in human THP-1 monocytes

(2018) Donatella D’Eliseo et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Review of the Antiviral Role of Green Tea Catechins

(2017) et al.   MOLECULES

Salidroside Inhibits HMGB1 Acetylation and Release through Upregulation of SirT1 during Inflammation

(2017) Zhilin Qi et al.   Oxidative Medicine and Cellular Longevity

Why is the flu vaccine so mediocre?

(2017) Jon Cohen   SCIENCE

Inhibition of influenza A virus infection by ginsenosides

(2017) Wei Dong et al.   PLoS One

Resveratrol treatment reveals a novel role for HMGB1 in regulation of the type 1 interferon response in dengue virus infection

(2017) Nurhafiza Zainal et al.   Scientific Reports

Salidroside ameliorates sepsis-induced acute lung injury and mortality via downregulating NF-κB and HMGB1 pathways through the upregulation of SIRT1

(2017) Kuo-Cheng Lan et al.   Scientific Reports

Therapeutic targeting of HMGB1 during experimental sepsis modulates the inflammatory cytokine profile to one associated with improved clinical outcomes

(2017) Natalie E. Stevens et al.   Scientific Reports

Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo

(2016) Gahee Min et al.   ARCHIVES OF PHARMACAL RESEARCH

Ameliorative effect of a rarely occurring C-methylrotenoid on HMGB1-induced septic responses in vitro and in vivo

(2016) Eun-Ju Yang et al.   BIOCHEMICAL PHARMACOLOGY

Prunella vulgaris L. active components and their hypoglycemic and antinociceptive effects in alloxan-induced diabetic mice

(2016) K. Raafat et al.   BIOMEDICINE & PHARMACOTHERAPY

Anti-influenza Virus Effects of Catechins: A Molecular and Clinical Review

(2016) Kazuke Ide et al.   CURRENT MEDICINAL CHEMISTRY

Aconitum carmichaelii Debeaux, cultivated as a medicinal plant in western China

(2016) Ma Yu et al.   GENETIC RESOURCES AND CROP EVOLUTION

Protective Effect of Brown Alga Phlorotannins against Hyper-inflammatory Responses in Lipopolysaccharide-Induced Sepsis Models

(2016) Yeong-In Yang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Aqueous extract from Aconitum carmichaelii Debeaux reduces liver injury in rats via regulation of HMGB1/TLR4/NF-ΚB/caspase-3 and PCNA signaling pathways

(2016) Jian-Xing Luo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cancer Preventive Activities of Tea Catechins

(2016) Chung Yang et al.   MOLECULES

Pulmonary Angiotensin-Converting Enzyme 2 (ACE2) and Inflammatory Lung Disease

(2016) Hongpeng Jia   SHOCK

Ameliorative Effect of Aspalathin and Nothofagin from Rooibos (Aspalathus linearis) on HMGB1-Induced Septic Responses In Vitro and In Vivo

(2015) Wonhwa Lee et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Antiseptic effect of vicenin-2 and scolymoside from Cyclopia subternata (honeybush) in response to HMGB1 as a late sepsis mediator in vitro and in vivo

(2015) Wonhwa Lee et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Human Coronavirus HKU1 Spike Protein UsesO-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme

(2015) Xingchuan Huang et al.   JOURNAL OF VIROLOGY

The antiviral and antimicrobial activities of licorice, a widely-used Chinese herb

(2015) Liqiang Wang et al.   Acta Pharmaceutica Sinica B

Green tea extract decreases starch digestion and absorption from a test meal in humans: a randomized, placebo-controlled crossover study

(2015) Klaudia Lochocka et al.   Scientific Reports

Baicalein Inhibits HMGB1 Release and MMP-2/-9 Expression in Lipopolysaccharide-Induced Cardiac Hypertrophy

(2014) Huai-Min Chen et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

(−)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes

(2014) Hsiu-Chen Huang et al.   ANTIVIRAL RESEARCH

HSPA5 is an essential host factor for Ebola virus infection

(2014) St. Patrick Reid et al.   ANTIVIRAL RESEARCH

Protective effect of quercetin on lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammatory cell influx

(2014) Lian Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

High HMGB1 level is associated with poor outcome of septicemic melioidosis

(2014) Jaruek Charoensup et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Systemic Release of High Mobility Group Box 1 Protein during Severe Murine Influenza

(2014) L. M. Alleva et al.   JOURNAL OF IMMUNOLOGY

A Small Molecule Inhibits Virion Attachment to Heparan Sulfate- or Sialic Acid-Containing Glycans

(2014) Che C. Colpitts et al.   JOURNAL OF VIROLOGY

Composition and inhibitory activities towards digestive enzymes of polyphenolic-rich fractions of Davidson's plum and quandong

(2014) Karunrat Sakulnarmrat et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Anti-hepatitis C virus compounds obtained fromGlycyrrhiza uralensis and otherGlycyrrhizaspecies

(2014) Myrna Adianti et al.   MICROBIOLOGY AND IMMUNOLOGY

Unknown

(2014) Daolin Tang et al.   MOLECULAR MEDICINE

Inhibition of IRAK-4 activity for rescuing endotoxin LPS-induced septic mortality in mice by lonicerae flos extract

(2013) Sun Hong Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Luteolin exhibits anti-inflammatory effects by blocking the activity of heat shock protein 90 in macrophages

(2013) Dan Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dieckol, a SARS-CoV 3CLpro inhibitor, isolated from the edible brown algae Ecklonia cava

(2013) Ji-Young Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Induction of HO-1 through p38 MAPK/Nrf2 signaling pathway by ethanol extract of Inula helenium L. reduces inflammation in LPS-activated RAW 264.7 cells and CLP-induced septic mice

(2013) Eun Jung Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Middle East Respiratory Syndrome Coronavirus Infection Mediated by the Transmembrane Serine Protease TMPRSS2

(2013) Kazuya Shirato et al.   JOURNAL OF VIROLOGY

Unknown

(2013) Chan-Ho Lee et al.   MOLECULAR MEDICINE

Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13

(2012) Mi-Sun Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Study of Astragalus mongholicus polysaccharides on endothelial cells permeability induced by HMGB1

(2012) Yun-Jiang Zheng et al.   CARBOHYDRATE POLYMERS

Berry components inhibit α-glucosidase in vitro: Synergies between acarbose and polyphenols from black currant and rowanberry

(2012) Ashley S. Boath et al.   FOOD CHEMISTRY

Barrier protective effects of rosmarinic acid on HMGB1-induced inflammatory responses in vitro and in vivo

(2012) Eun-Ju Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and Deltacoronavirus

(2012) P. C. Y. Woo et al.   JOURNAL OF VIROLOGY

Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts

(2012) Stephanie Bertram et al.   PLoS One

Inhibition of Intercellular Adhesion in Herpex Simplex Virus Infection by Glycyrrhizin

(2011) Wen Huang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Antivirus and immune enhancement activities of sulfated polysaccharide from Angelica sinensis

(2011) Tiehong Yang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

(2011) I. Glowacka et al.   JOURNAL OF VIROLOGY

Why do RNA viruses recombine?

(2011) Etienne Simon-Loriere et al.   NATURE REVIEWS MICROBIOLOGY

Ethanol Extract of Prunella vulgaris var. lilacina Inhibits HMGB1 Release by Induction of Heme Oxygenase-1 in LPS-activated RAW 264.7 Cells and CLP-induced Septic Mice

(2011) Min Soo Jun et al.   PHYTOTHERAPY RESEARCH

Cytokine Response Patterns in Severe Pandemic 2009 H1N1 and Seasonal Influenza among Hospitalized Adults

(2011) Nelson Lee et al.   PLoS One

Inhibition of HIV-1 infection by aqueous extracts of Prunella vulgaris L.

(2011) ChoonSeok Oh et al.   Virology Journal

Anti-inflammatory/Anti-oxidative Stress Activities and Differential Regulation of Nrf2-Mediated Genes by Non-Polar Fractions of Tea Chrysanthemum zawadskii and Licorice Glycyrrhiza uralensis

(2010) Tien-Yuan Wu et al.   AAPS Journal

Stimulation of Alpha7 Nicotinic Acetylcholine Receptor by Nicotine Attenuates Inflammatory Response in Macrophages and Improves Survival in Experimental Model of Sepsis Through Heme Oxygenase-1 Induction

(2010) Konstantin Tsoyi et al.   ANTIOXIDANTS & REDOX SIGNALING

Carboxylated N-glycans on RAGE promote S100A12 binding and signaling

(2010) Geetha Srikrishna et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2

(2010) S. Matsuyama et al.   JOURNAL OF VIROLOGY

Dual inhibitory effect of Glycyrrhiza glabra (GutGard™) on COX and LOX products

(2010) C.V. Chandrasekaran et al.   PHYTOMEDICINE

Beneficial effects of green tea: A literature review

(2010) Sabu M Chacko et al.   Chinese Medicine

The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice

(2008) Yumiko Imai et al.   EXPERIMENTAL PHYSIOLOGY

Dengue virus infection induces passive release of high mobility group box 1 protein by epithelial cells

(2008) Lien-Cheng Chen et al.   JOURNAL OF INFECTION

Elevated levels of high mobility group box chromosomal protein-1 (HMGB-1) in sera from patients with severe bacterial pneumonia coinfected with influenza virus

(2008) Kosuke Kosai et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES