Maternal Immune Activation Induces Neuroinflammation and Cortical Synaptic Deficits in the Adolescent Rat Offspring

Sex-dependent behavioral deficits and neuropathology in a maternal immune activation model of autism

(2019) Obelia Haida et al.   Translational Psychiatry

Maternal immune activation with staphylococcal enterotoxin A produces unique behavioral changes in C57BL/6 mouse offspring

(2018) Ruthy Glass et al.   BRAIN BEHAVIOR AND IMMUNITY

PSD95: A synaptic protein implicated in schizophrenia or autism?

(2018) Austin A. Coley et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Prenatal stress and genetic risk: How prenatal stress interacts with genetics to alter risk for psychiatric illness

(2018) Parker W. Abbott et al.   PSYCHONEUROENDOCRINOLOGY

The Impact of Systemic Inflammation on Neurodevelopment

(2018) Nona M. Jiang et al.   TRENDS IN MOLECULAR MEDICINE

Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder

(2017) M V Lombardo et al.   MOLECULAR PSYCHIATRY

SHANK proteins: roles at the synapse and in autism spectrum disorder

(2017) Patricia Monteiro et al.   NATURE REVIEWS NEUROSCIENCE

Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood

(2017) Wandert Schaafsma et al.   NEUROBIOLOGY OF DISEASE

Selol, an organic selenium donor, prevents lipopolysaccharide-induced oxidative stress and inflammatory reaction in the rat brain

(2017) Agnieszka Dominiak et al.   NEUROCHEMISTRY INTERNATIONAL

Maternal Immune Activation Causes Behavioral Impairments and Altered Cerebellar Cytokine and Synaptic Protein Expression

(2017) Gurudutt Pendyala et al.   NEUROPSYCHOPHARMACOLOGY

Brain interference: Revisiting the role of IFNγ in the central nervous system

(2017) S. Monteiro et al.   PROGRESS IN NEUROBIOLOGY

Development of cortical thickness and surface area in autism spectrum disorder

(2017) Vincent T. Mensen et al.   NeuroImage-Clinical

Maternal inflammation linearly exacerbates offspring age-related changes of spatial learning and memory, and neurobiology until senectitude

(2016) Xue-Wei Li et al.   BEHAVIOURAL BRAIN RESEARCH

Prenatal immune activation causes hippocampal synaptic deficits in the absence of overt microglia anomalies

(2016) Sandra Giovanoli et al.   BRAIN BEHAVIOR AND IMMUNITY

Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models

(2016) Verónica Martínez-Cerdeño   Developmental Neurobiology

Phenotyping, Etiological Factors, and Biomarkers

(2016) David Q. Beversdorf   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

SNARE complex in developmental psychiatry: neurotransmitter exocytosis and beyond

(2016) Renata Basso Cupertino et al.   JOURNAL OF NEURAL TRANSMISSION

Sodium Butyrate, a Histone Deacetylase Inhibitor, Exhibits Neuroprotective/Neurogenic Effects in a Rat Model of Neonatal Hypoxia-Ischemia

(2016) Malgorzata Ziemka-Nalecz et al.   MOLECULAR NEUROBIOLOGY

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes

(2016) Yuan Mei et al.   NATURE

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

(2016) Yang Zhou et al.   NEURON

HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS

(2015) Susanna Roberts et al.   DEPRESSION AND ANXIETY

Sequential activation of microglia and astrocyte cytokine expression precedes increased iba-1 or GFAP immunoreactivity following systemic immune challenge

(2015) Diana M. Norden et al.   GLIA

Shank synaptic scaffold proteins: keys to understanding the pathogenesis of autism and other synaptic disorders

(2015) Carlo Sala et al.   JOURNAL OF NEUROCHEMISTRY

Syntaxin 1B is important for mouse postnatal survival and proper synaptic function at the mouse neuromuscular junctions

(2015) Yuan-Ju Wu et al.   JOURNAL OF NEUROPHYSIOLOGY

From the genetic architecture to synaptic plasticity in autism spectrum disorder

(2015) Thomas Bourgeron   NATURE REVIEWS NEUROSCIENCE

The Lipoxygenases: Their Regulation and Implication in Alzheimer’s Disease

(2015) Grzegorz A. Czapski et al.   NEUROCHEMICAL RESEARCH

The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders

(2015) G.Z. Réus et al.   NEUROSCIENCE

The Poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery

(2015) Sonali Reisinger et al.   PHARMACOLOGY & THERAPEUTICS

Prenatal LPS-exposure – a neurodevelopmental rat model of schizophrenia – differentially affects cognitive functions, myelination and parvalbumin expression in male and female offspring

(2015) Lena Wischhof et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Lipopolysaccharide Exposure Induces Maternal Hypozincemia, and Prenatal Zinc Treatment Prevents Autistic-Like Behaviors and Disturbances in the Striatal Dopaminergic and mTOR Systems of Offspring

(2015) Thiago Berti Kirsten et al.   PLoS One

Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

(2014) Dalila Pinto et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Serological Documentation of Maternal Influenza Exposure and Bipolar Disorder in Adult Offspring

(2014) Sarah E. Canetta et al.   AMERICAN JOURNAL OF PSYCHIATRY

Elevated Maternal C-Reactive Protein and Increased Risk of Schizophrenia in a National Birth Cohort

(2014) Sarah Canetta et al.   AMERICAN JOURNAL OF PSYCHIATRY

The risk for behavioural deficits is determined by the maternal immune response to prenatal immune challenge in a neurodevelopmental model

(2014) S. Missault et al.   BRAIN BEHAVIOR AND IMMUNITY

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Synaptic proteins and receptors defects in autism spectrum disorders

(2014) Jianling Chen et al.   Frontiers in Cellular Neuroscience

Involvement of Synaptic Genes in the Pathogenesis of Autism Spectrum Disorders: The Case of Synapsins

(2014) Silvia Giovedí et al.   Frontiers in Pediatrics

Prenatal Poly(I:C) Exposure and Other Developmental Immune Activation Models in Rodent Systems

(2013) Urs Meyer   BIOLOGICAL PSYCHIATRY

SYN2 is an autism predisposing gene: loss-of-function mutations alter synaptic vesicle cycling and axon outgrowth

(2013) Anna Corradi et al.   HUMAN MOLECULAR GENETICS

Neuroinflammation and psychiatric illness

(2013) Souhel Najjar et al.   Journal of Neuroinflammation

Elevated maternal C-reactive protein and autism in a national birth cohort

(2013) A S Brown et al.   MOLECULAR PSYCHIATRY

Brain IL-6 and autism

(2013) H. Wei et al.   NEUROSCIENCE

Shank mutant mice as an animal model of autism

(2013) J. Yoo et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Aberrant neural synchrony in the maternal immune activation model: using translatable measures to explore targeted interventions

(2013) Desiree D. Dickerson et al.   Frontiers in Behavioral Neuroscience

Gestational Influenza and Bipolar Disorder in Adult Offspring

(2013) Raveen Parboosing et al.   JAMA Psychiatry

Perinatal stress, brain inflammation and risk of autism-Review and proposal

(2012) Asimenia Angelidou et al.   BMC Pediatrics

Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response

(2012) Devon B. Oskvig et al.   BRAIN BEHAVIOR AND IMMUNITY

Oxidative stress-related biomarkers in autism: Systematic review and meta-analyses

(2012) Alessandra Frustaci et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypoactivity of the central dopaminergic system and autistic-like behavior induced by a single early prenatal exposure to lipopolysaccharide

(2012) Thiago B. Kirsten et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Neuropoietic cytokines in normal brain development and neurodevelopmental disorders

(2012) H.B. Stolp   MOLECULAR AND CELLULAR NEUROSCIENCE

Scaffolding Proteins of the Post-synaptic Density Contribute to Synaptic Plasticity by Regulating Receptor Localization and Distribution: Relevance for Neuropsychiatric Diseases

(2012) Felice Iasevoli et al.   NEUROCHEMICAL RESEARCH

Brain Region-Specific Glutathione Redox Imbalance in Autism

(2012) Abha Chauhan et al.   NEUROCHEMICAL RESEARCH

Autism After Infection, Febrile Episodes, and Antibiotic Use During Pregnancy: An Exploratory Study

(2012) H. O. Atladottir et al.   PEDIATRICS

Altered Neurotrophin, Neuropeptide, Cytokines and Nitric Oxide Levels in Autism

(2012) M.H.F. Tostes et al.   PHARMACOPSYCHIATRY

Communication and wiring in the cortical connectome

(2012) Julian M. L. Budd et al.   Frontiers in Neuroanatomy

Prioritization of candidate genes for attention deficit hyperactivity disorder by computational analysis of multiple data sources

(2012) Suhua Chang et al.   Protein & Cell

Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain

(2012) S Rose et al.   Translational Psychiatry

Maternal infection during late pregnancy increases anxiety- and depression-like behaviors with increasing age in male offspring

(2011) Mohsen Enayati et al.   BRAIN RESEARCH BULLETIN

Networking in Autism: Leveraging Genetic, Biomarker and Model System Findings in the Search for New Treatments

(2011) Jeremy Veenstra-VanderWeele et al.   NEUROPSYCHOPHARMACOLOGY

Maternal Immune Activation and Autism Spectrum Disorder: Interleukin-6 Signaling as a Key Mechanistic Pathway

(2011) E. Carla Parker-Athill et al.   NEUROSIGNALS

Schizophrenia and Autism: Both Shared and Disorder-Specific Pathogenesis Via Perinatal Inflammation?

(2011) URS MEYER et al.   PEDIATRIC RESEARCH

Abnormalities in connectivity of white-matter tracts in patients with familial and non-familial schizophrenia

(2011) Q. Wang et al.   PSYCHOLOGICAL MEDICINE

The Postsynaptic Organization of Synapses

(2011) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

Prenatal Infection and Schizophrenia: A Review of Epidemiologic and Translational Studies

(2010) Alan S. Brown et al.   AMERICAN JOURNAL OF PSYCHIATRY

Activation of the maternal immune system induces endocrine changes in the placenta via IL-6

(2010) Elaine Y. Hsiao et al.   BRAIN BEHAVIOR AND IMMUNITY

Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome

(2010) Paul Ashwood et al.   BRAIN BEHAVIOR AND IMMUNITY

Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting

(2010) Catalina Betancur   BRAIN RESEARCH

The benefit of directly comparing autism and schizophrenia for revealing mechanisms of social cognitive impairment

(2010) Noah J. Sasson et al.   Journal of Neurodevelopmental Disorders

Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior

(2010) J. Blundell et al.   JOURNAL OF NEUROSCIENCE

Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation

(2010) Charlton Cheung et al.   PLoS One

Replication study of Japanese cohorts supports the role of STX1A in autism susceptibility

(2010) Kazuhiko Nakamura et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Neonatal Behavioral Changes in Rats With Gestational Exposure to Lipopolysaccharide: A Prenatal Infection Model for Developmental Neuropsychiatric Disorders

(2010) M. Baharnoori et al.   SCHIZOPHRENIA BULLETIN

Elevated immune response in the brain of autistic patients

(2009) Xiaohong Li et al.   JOURNAL OF NEUROIMMUNOLOGY

New insights into the relationship of neurogenesis and affect: tickling induces hippocampal cell proliferation in rats emitting appetitive 50-kHz ultrasonic vocalizations

(2009) M. Wöhr et al.   NEUROSCIENCE

The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders

(2009) Catalina Betancur et al.   TRENDS IN NEUROSCIENCES

Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases

(2008) Avik Roy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Deficient maternal care resulting from immunological stress during pregnancy is associated with a sex-dependent enhancement of conditioned fear in the offspring

(2008) Severin Schwendener et al.   Journal of Neurodevelopmental Disorders

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice

(2007) Urs Meyer et al.   BRAIN BEHAVIOR AND IMMUNITY