Phenotypical characterization of regulatory T cells in humans and rodents

Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry

(2015) Saskia J. A. M. Santegoets et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Neonatal regulatory T cells have reduced capacity to suppress dendritic cell function

(2015) Cesar M. Rueda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A subpopulation of CD103posICOSposTreg cells occurs at high frequency in lymphopenic mice and represents a lymph node specific differentiation stage

(2015) Thomas Barthlott et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of chorioamnionitis on regulatory T cells in moderate/late preterm neonates

(2015) Cesar M. Rueda et al.   HUMAN IMMUNOLOGY

Captopril inhibits maturation of dendritic cells and maintains their tolerogenic property in atherosclerotic rats

(2015) Hong-qi Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

PD-1 Upregulated on Regulatory T Cells during Chronic Virus Infection Enhances the Suppression of CD8+T Cell Immune Response via the Interaction with PD-L1 Expressed on CD8+T Cells

(2015) Hyo Jin Park et al.   JOURNAL OF IMMUNOLOGY

GITR subverts Foxp3+ Tregs to boost Th9 immunity through regulation of histone acetylation

(2015) Xiang Xiao et al.   Nature Communications

Glucocorticoid-Induced Tumour Necrosis Factor Receptor-Related Protein: A Key Marker of Functional Regulatory T Cells

(2015) Simona Ronchetti et al.   Journal of Immunology Research

Statins Increase the Frequency of Circulating CD4+FOXP3+Regulatory T Cells in Healthy Individuals

(2015) Ana Lucía Rodríguez-Perea et al.   Journal of Immunology Research

Differences in Expression Level of Helios and Neuropilin-1 Do Not Distinguish Thymus-Derived from Extrathymically-Induced CD4+Foxp3+ Regulatory T Cells

(2015) Edyta Szurek et al.   PLoS One

CD4+ Foxp3+Regulatory T Cells in Autoimmune Orchitis: Phenotypic and Functional Characterization

(2014) Patricia Jacobo et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Protective effect of CD4+CD25highCD127low regulatory T cells in renal ischemia–reperfusion injury

(2014) Cao Jun et al.   CELLULAR IMMUNOLOGY

Foxp3+regulatory T-cell homeostasis quantitatively differs in murine peripheral lymph nodes and spleen

(2014) Pedro Milanez-Almeida et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PD-1 regulates extrathymic regulatory T-cell differentiation

(2014) Xiufen Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cerebral regulatory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10

(2014) Luokun Xie et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CTLA4 Expression Is an Indicator and Regulator of Steady-State CD4+FoxP3+ T Cell Homeostasis

(2014) A. L. Tang et al.   JOURNAL OF IMMUNOLOGY

Ex Vivo Generated Regulatory T Cells Modulate Experimental Autoimmune Myasthenia Gravis

(2014) R. Aricha et al.   JOURNAL OF IMMUNOLOGY

Acquisition of Suppressive Function by Activated Human CD4+CD25- T Cells Is Associated with the Expression of CTLA-4 Not FoxP3

(2014) Y. Zheng et al.   JOURNAL OF IMMUNOLOGY

Differential Regulation of Human IL-7 Receptor   Expression by IL-7 and TCR Signaling

(2014) N. L. Alves et al.   JOURNAL OF IMMUNOLOGY

Functional Regulatory T Cells Accumulate in Aged Hosts and Promote Chronic Infectious Disease Reactivation

(2014) C. S. Lages et al.   JOURNAL OF IMMUNOLOGY

Effector T Cells Boost Regulatory T Cell Expansion by IL-2, TNF, OX40, and Plasmacytoid Dendritic Cells Depending on the Immune Context

(2014) Audrey Baeyens et al.   JOURNAL OF IMMUNOLOGY

IL-2Rβ–Dependent Signaling and CD103 Functionally Cooperate To Maintain Tolerance in the Gut Mucosa

(2014) Xiaomei Yuan et al.   JOURNAL OF IMMUNOLOGY

Phenotype Alterations in Regulatory T-Cell Subsets in Primary HIV Infection and Identification of Tr1-like Cells as the Main Interleukin 10-Producing CD4+ T Cells

(2014) M. F. Chevalier et al.   JOURNAL OF INFECTIOUS DISEASES

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells

(2014) Shawn A Mahmud et al.   NATURE IMMUNOLOGY

Role of Lymphocyte Activation Gene-3 (Lag-3) in Conventional and Regulatory T Cell Function in Allogeneic Transplantation

(2014) Emanuela I. Sega et al.   PLoS One

Application and effects of mouse Foxp3 antibody and fixation/permeabilization buffer on the detection of CD4+ regulatory T cells in various mammal species

(2013) Y.L. Sun et al.   GENETICS AND MOLECULAR RESEARCH

Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response

(2013) Samantha L. Bailey-Bucktrout et al.   IMMUNITY

CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets

(2013) Kate S. Smigiel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antibodies Targeting Human OX40 Expand Effector T Cells and Block Inducible and Natural Regulatory T Cell Function

(2013) K. S. Voo et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells: recommendations to simplify the nomenclature

(2013) Abul K Abbas et al.   NATURE IMMUNOLOGY

Incomplete Normalization of Regulatory T-Cell Frequency in the Gut Mucosa of Colombian HIV-Infected Patients Receiving Long-Term Antiretroviral Treatment

(2013) Cesar M. Rueda et al.   PLoS One

OMIP-015: Human regulatory and activated T-cells without intracellular staining

(2012) Yolanda D. Mahnke et al.   CYTOMETRY PART A

CD4+CD25+CD127low/− T Cells: A More Specific Treg Population in Human Peripheral Blood

(2012) Ning Yu et al.   INFLAMMATION

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(2012) Shohreh Issazadeh-Navikas et al.   MOLECULAR MEDICINE

Role of Donor-Specific Regulatory T Cells in Long-Term Acceptance of Rat Hind Limb Allograft

(2012) Yaojun Wang et al.   PLoS One

Regulatory T-Cells: Diverse Phenotypes Integral to Immune Homeostasis and Suppression

(2012) Richard A. Peterson   TOXICOLOGIC PATHOLOGY

OMIP-004: In-depth characterization of human T regulatory cells

(2011) Angélique Biancotto et al.   CYTOMETRY PART A

Cryopreservation modulates the detection of regulatory T cell markers

(2011) Sebastian Sattui et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

OX40:OX40L axis: emerging targets for improving poxvirus-based CD8+ T-cell vaccines against respiratory viruses

(2011) John Goulding et al.   IMMUNOLOGICAL REVIEWS

Increased Frequency of Regulatory T Cells Accompanies Increased Immune Activation in Rectal Mucosae of HIV-Positive Noncontrollers

(2011) J. M. Shaw et al.   JOURNAL OF VIROLOGY

Regulatory T cells Contribute to Diabetes Protection in Lipopolysaccharide-Treated Non-Obese Diabetic Mice

(2011) I. Caramalho et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Association of two clones allows for optimal detection of human FOXP3

(2010) Pietro Presicce et al.   CYTOMETRY PART A

Increased CD127 expression on activated FOXP3+CD4+ regulatory T cells

(2010) Federico Simonetta et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells

(2010) Gongxian Liao et al.   INTERNATIONAL IMMUNOLOGY

OX40 is required for regulatory T cell–mediated control of colitis

(2010) Thibault Griseri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Foxp3+ CD4 Regulatory T Cells Limit Pulmonary Immunopathology by Modulating the CD8 T Cell Response during Respiratory Syncytial Virus Infection

(2010) R. B. Fulton et al.   JOURNAL OF IMMUNOLOGY

The importance of Foxp3 antibody and fixation/permeabilization buffer combinations in identifying CD4+CD25+Foxp3+regulatory T cells

(2009) Jacqueline P. Law et al.   CYTOMETRY PART A

Neuropilin‐1 is not a marker of human Foxp3+Treg

(2009) Pierre Milpied et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

CD4+CD25+/hiCD127loPhenotype Does Not Accurately Identify Regulatory T Cells in All Populations of HIV‐Infected Persons

(2009) Maria del Mar del Pozo‐Balado et al.   JOURNAL OF INFECTIOUS DISEASES

Aging and human CD4+ regulatory T cells

(2009) Kyung-A. Hwang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

THE EFFECT OF HIGH-MOBILITY GROUP BOX 1 PROTEIN ON ACTIVITY OF REGULATORY T CELLS AFTER THERMAL INJURY IN RATS

(2009) Li-feng Huang et al.   SHOCK

Increased production of soluble CTLA-4 in patients with spondylarthropathies correlates with disease activity

(2009) Éric Toussirot et al.   ARTHRITIS RESEARCH & THERAPY

Increased Foxp3+ CD4+ Regulatory T Cells with Intact Suppressive Activity but Altered Cellular Localization in Murine Lupus

(2008) Jun Abe et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Level, phenotype and activation status of CD4+FoxP3+regulatory T cells in patients chronically infected with human immunodeficiency virus and/or hepatitis C virus

(2008) N. I. Rallón et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

High frequency and proliferation of CD4+FOXP3+ Treg in HIV-1-infected patients with low CD4 counts

(2008) Xiuqiong Bi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction

(2008) Qizhi Tang et al.   IMMUNITY

Increased circulating regulatory T cells (CD4+CD25+CD127−) contribute to lymphocyte anergy in septic shock patients

(2008) Fabienne Venet et al.   INTENSIVE CARE MEDICINE

Recent thymic origin, differentiation, and turnover of regulatory T cells

(2008) Nicholas H. E. Mabarrack et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

(2008) Y. Onishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE

Compromised CD4+ CD25highregulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level

(2007) Koen Venken et al.   IMMUNOLOGY