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Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness

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Variability in the analysis of a single neuroimaging dataset by many teams

(2020) Rotem Botvinik-Nezer et al.   NATURE

The genetic architecture of the human cerebral cortex

(2020) Katrina L. Grasby et al.   SCIENCE

Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model

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ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

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The Challenges and Opportunities of Small Effects

(2019) Martin P. Paulus et al.   JAMA Psychiatry

Mapping causal pathways from genetics to neuropsychiatric disorders using genome-wide imaging genetics: current status and future directions

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Brain Imaging of the Cortex in ADHD: A Coordinated Analysis of Large-Scale Clinical and Population-Based Samples

(2019) Martine Hoogman et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genome-wide association study identifies 30 loci associated with bipolar disorder

(2019) Eli A. Stahl et al.   NATURE GENETICS

Higher in vivo Cortical Intracellular Volume Fraction Associated with Lithium Therapy in Bipolar Disorder: A Multicenter NODDI Study

(2019) Samuel Sarrazin et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Brain age in bipolar disorders: Effects of lithium treatment

(2019) Holly Van Gestel et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

The association between familial risk and brain abnormalities is disease-specific: an ENIGMA–Relatives study of schizophrenia and bipolar disorder

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Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study

(2019) Julio E. Villalón-Reina et al.   MOLECULAR PSYCHIATRY

Machine learning and big data analytics in bipolar disorder: A position paper from the International Society for Bipolar Disorders Big Data Task Force

(2019) Ives C. Passos et al.   BIPOLAR DISORDERS

White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group

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Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals

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Population-Based Mapping of Polygenic Risk for Schizophrenia on the Human Brain: New Opportunities to Capture the Dimensional Aspects of Severe Mental Disorders

(2019) Lars T. Westlye et al.   BIOLOGICAL PSYCHIATRY

White matter microstructural alterations across four major psychiatric disorders: mega-analysis study in 2937 individuals

(2019) Daisuke Koshiyama et al.   MOLECULAR PSYCHIATRY

Genetic architecture of subcortical brain structures in 38,851 individuals

(2019) Claudia L. Satizabal et al.   NATURE GENETICS

Using network analysis to examine links between individual depressive symptoms, inflammatory markers, and covariates

(2019) E. I. Fried et al.   PSYCHOLOGICAL MEDICINE

Bipolar disorder with and without a history of psychotic features: fMRI correlates of sustained attention

(2019) Gianna Sepede et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Cortical and Subcortical Brain Morphometry Differences Between Patients With Autism Spectrum Disorder and Healthy Individuals Across the Lifespan: Results From the ENIGMA ASD Working Group

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Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group

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Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium

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Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia

(2018) Mark W. Logue et al.   BIOLOGICAL PSYCHIATRY

Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study

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Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

(2018) Douglas M. Ruderfer et al.   CELL

Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity

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Biomarkers in mood disorders: Are we there yet?

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Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size

(2018) Daqiang Sun et al.   MOLECULAR PSYCHIATRY

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Differentiating between bipolar and unipolar depression in functional and structural MRI studies

(2018) Kyu-Man Han et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The world’s largest set of brain scans are helping reveal the workings of the mind and how diseases ravage the brain

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Analysis of shared heritability in common disorders of the brain

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Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

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Bipolar disorders

(2018) Eduard Vieta et al.   Nature Reviews Disease Primers

Maturation of the Human Cerebral Cortex During Adolescence: Myelin or Dendritic Arbor?

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Using structural MRI to identify bipolar disorders – 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group

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Mega-Analysis of Gray Matter Volume in Substance Dependence: General and Substance-Specific Regional Effects

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Mapping the Heterogeneous Phenotype of Schizophrenia and Bipolar Disorder Using Normative Models

(2018) Thomas Wolfers et al.   JAMA Psychiatry

Inferring pathobiology from structural MRI in schizophrenia and bipolar disorder: Modeling head motion and neuroanatomical specificity

(2017) Nailin Yao et al.   HUMAN BRAIN MAPPING

Genetic influences on individual differences in longitudinal changes in global and subcortical brain volumes: Results of the ENIGMA plasticity working group

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Acknowledging and Overcoming Nonreproducibility in Basic and Preclinical Research

(2017) John P. A. Ioannidis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group

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Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

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Imaging microstructure in the living human brain: A viewpoint

(2017) Tomáš Paus   NEUROIMAGE

Emerging Global Initiatives in Neurogenetics: The Enhancing Neuroimaging Genetics through Meta-analysis (ENIGMA) Consortium

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Novel genetic loci associated with hippocampal volume

(2017) Derrek P. Hibar et al.   Nature Communications

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder

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Low statistical power in biomedical science: a review of three human research domains

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Course and Outcome after the First Manic Episode in Patients with Bipolar Disorder: Prospective 12-Month Data from the Systematic Treatment Optimization Program for Early Mania Project

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Cortical thickness in bipolar disorder: a systematic review

(2016) Lindsay C Hanford et al.   BIPOLAR DISORDERS

Bipolar disorders, type 2 diabetes mellitus, and the brain

(2016) Tomas Hajek et al.   CURRENT OPINION IN PSYCHIATRY

The association of antipsychotic medication and lithium with brain measures in patients with bipolar disorder

(2016) Lucija Abramovic et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Trajectory and predictors of quality of life in first episode psychotic mania

(2016) Meredith Oldis et al.   JOURNAL OF AFFECTIVE DISORDERS

Characteristics and heterogeneity of schizoaffective disorder compared with unipolar depression and schizophrenia – a systematic literature review and meta-analysis

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Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group

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Subcortical volumetric abnormalities in bipolar disorder

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Multimodal population brain imaging in the UK Biobank prospective epidemiological study

(2016) Karla L Miller et al.   NATURE NEUROSCIENCE

Novel genetic loci underlying human intracranial volume identified through genome-wide association

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Motion and morphometry in clinical and nonclinical populations

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Longitudinal studies: An essential component for complex psychiatric disorders

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Etiologic, Phenomenologic, and Endophenotypic Overlap of Schizophrenia and Bipolar Disorder

(2015) Godfrey D. Pearlson   Annual Review of Clinical Psychology

Manic episodes are related to changes in frontal cortex: a longitudinal neuroimaging study of bipolar disorder 1

(2015) Christoph Abé et al.   BRAIN

Developmental trajectory of cognitive impairment in bipolar disorder: Comparison with schizophrenia

(2015) Emre Bora   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Erratum: Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium

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Evaluating historical candidate genes for schizophrenia

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Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group

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Common genetic variants influence human subcortical brain structures

(2015) Derrek P. Hibar et al.   NATURE

Neural correlates of negative emotion processing in bipolar disorder

(2015) Gianna Sepede et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A Critical Appraisal of Neuroimaging Studies of Bipolar Disorder: Toward a New Conceptualization of Underlying Neural Circuitry and a Road Map for Future Research

(2014) Mary L. Phillips et al.   AMERICAN JOURNAL OF PSYCHIATRY

The NIMH Research Domain Criteria (RDoC) Project: Precision Medicine for Psychiatry

(2014) Thomas R. Insel   AMERICAN JOURNAL OF PSYCHIATRY

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

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Biological insights from 108 schizophrenia-associated genetic loci

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Insulin Resistance, Diabetes Mellitus and Brain Structure in Bipolar Disorders

(2014) Tomas Hajek et al.   NEUROPSYCHOPHARMACOLOGY

A Multicenter Tractography Study of Deep White Matter Tracts in Bipolar I Disorder

(2014) Samuel Sarrazin et al.   JAMA Psychiatry

Network Analysis: An Integrative Approach to the Structure of Psychopathology

(2013) Denny Borsboom et al.   Annual Review of Clinical Psychology

Impaired Anatomical Connectivity and Related Executive Functions: Differentiating Vulnerability and Disease Marker in Bipolar Disorder

(2013) Julia Linke et al.   BIOLOGICAL PSYCHIATRY

Structural Abnormalities in Bipolar Euthymia: A Multicontrast Molecular Diffusion Imaging Study

(2013) Erick Jorge Canales-Rodríguez et al.   BIOLOGICAL PSYCHIATRY

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

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Power failure: why small sample size undermines the reliability of neuroscience

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Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA–DTI working group

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The societal cost of bipolar disorder in Sweden

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Cortical Volume, Surface Area, and Thickness in Schizophrenia and Bipolar Disorder

(2012) Lars M. Rimol et al.   BIOLOGICAL PSYCHIATRY

Brain Structural Signature of Familial Predisposition for Bipolar Disorder: Replicable Evidence For Involvement of the Right Inferior Frontal Gyrus

(2012) Tomas Hajek et al.   BIOLOGICAL PSYCHIATRY

Impaired sustained attention in euthymic bipolar disorder patients and non-affected relatives: an fMRI study

(2012) Gianna Sepede et al.   BIPOLAR DISORDERS

Smaller hippocampal volumes in patients with bipolar disorder are masked by exposure to lithium: a meta-analysis

(2012) Tomas Hajek et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

An anatomically comprehensive atlas of the adult human brain transcriptome

(2012) Michael J. Hawrylycz et al.   NATURE

Identification of common variants associated with human hippocampal and intracranial volumes

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NODDI: Practical in vivo neurite orientation dispersion and density imaging of the human brain

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Excess Significance Bias in the Literature on Brain Volume Abnormalities

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Prevalence and Correlates of Bipolar Spectrum Disorder in the World Mental Health Survey Initiative

(2011) Kathleen R. Merikangas et al.   ARCHIVES OF GENERAL PSYCHIATRY

Cortical Thickness and Subcortical Volumes in Schizophrenia and Bipolar Disorder

(2010) Lars M. Rimol et al.   BIOLOGICAL PSYCHIATRY

Imaging genetics—days of future past

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ALE meta-analysis of action observation and imitation in the human brain

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Lithium-Induced Gray Matter Volume Increase As a Neural Correlate of Treatment Response in Bipolar Disorder: A Longitudinal Brain Imaging Study

(2010) In Kyoon Lyoo et al.   NEUROPSYCHOPHARMACOLOGY

Functional connectivity between ventral prefrontal cortex and amygdala at low frequency in the resting state in bipolar disorder

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A Longitudinal Study of the Effects of Lithium Treatment on Prefrontal and Subgenual Prefrontal Gray Matter Volume in Treatment-Responsive Bipolar Disorder Patients

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A role for white matter abnormalities in the pathophysiology of bipolar disorder

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Abnormal Corpus Callosum Integrity in Bipolar Disorder: A Diffusion Tensor Imaging Study

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Why Most Discovered True Associations Are Inflated

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Amygdala volumes in mood disorders — Meta-analysis of magnetic resonance volumetry studies

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