Developmental patterns in human blood–brain barrier and blood–cerebrospinal fluid barrier ABC drug transporter expression

Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood–Brain Barrier Measured by Quantitative Targeted Proteomics

(2019) Sarah Billington et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Mind the Gaps: Ontogeny of Human Brain P-gp and Its Impact on Drug Toxicity

(2019) Jean-Marie Nicolas et al.   AAPS Journal

A comprehensive analysis of ontogeny of renal drug transporters: mRNA analyses, quantitative proteomics and localization

(2019) Kit Wun Kathy Cheung et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium

(2018) Raymond Evers et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants

(2018) Bianca D. van Groen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Investigation of the Importance of Multidrug Resistance-Associated Protein 4 (Mrp4/ Abcc4 ) in the Active Efflux of Anionic Drugs Across the Blood–Brain Barrier

(2017) Kayoko Kanamitsu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics

(2016) B Prasad et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group

(2015) KLR Brouwer et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Approaching Complete Inhibition of P-Glycoprotein at the Human Blood–Brain Barrier: An (R)-[11C]Verapamil PET Study

(2015) Martin Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The ontogeny of P-glycoprotein in the developing human blood–brain barrier: implication for opioid toxicity in neonates

(2015) Jessica Lam et al.   PEDIATRIC RESEARCH

Efflux transporters in blood-brain interfaces of the developing brain

(2015) Nathalie Strazielle et al.   Frontiers in Neuroscience

Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line hCMEC/D3 as a Human Blood–Brain Barrier Model

(2012) Sumio Ohtsuki et al.   MOLECULAR PHARMACEUTICS

Differential expression of ABC transporters (MDR1, MRP1, BCRP) in developing human embryos

(2011) A. Konieczna et al.   JOURNAL OF MOLECULAR HISTOLOGY

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

P-glycoprotein and breast cancer resistance protein expression and function at the blood–brain barrier and blood–cerebrospinal fluid barrier (choroid plexus) in streptozotocin-induced diabetes in rats

(2010) Valeska Reichel et al.   BRAIN RESEARCH

Regulation of hepatic ABCC transporters by xenobiotics and in disease states

(2010) Xinsheng Gu et al.   DRUG METABOLISM REVIEWS

Compartment-Specific Roles of ATP-Binding Cassette Transporters Define Differential Topotecan Distribution in Brain Parenchyma and Cerebrospinal Fluid

(2009) J. Shen et al.   CANCER RESEARCH

Safety of Morphine in Nonintubated Infants in the Neonatal Intensive Care Unit

(2009) Anna Taddio et al.   CLINICAL JOURNAL OF PAIN

ABC Transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) Expression in the Developing Human CNS

(2009) M. Daood et al.   NEUROPEDIATRICS