Hydroxychloroquine as a Preventive and Therapeutic Option in Preeclampsia – a Literature Review

Pre-eclampsia: pathophysiology and clinical implications

(2019) Graham J Burton et al.   BMJ-British Medical Journal

Pravastatin for early‐onset pre‐eclampsia: a randomised, blinded, placebo‐controlled trial

(2019) A Ahmed et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Hydroxychloroquine: An old drug with new relevance

(2018) E. A. SHIPPEY et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Placental Proinflammatory State and Maternal Endothelial Dysfunction in Preeclampsia

(2018) Jorge Valencia-Ortega et al.   GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Esomeprazole to treat women with preterm preeclampsia: a randomized placebo controlled trial

(2018) Catherine A. Cluver et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Clinicians should stop prescribing sildenafil for fetal growth restriction (FGR): comment from the STRIDER Consortium

(2018) K. M. Groom et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Preeclampsia: Novel Mechanisms and Potential Therapeutic Approaches

(2018) Zaher Armaly et al.   Frontiers in Physiology

Aspirin prevents TNF-α-induced endothelial cell dysfunction by regulating the NF-κB-dependent miR-155/eNOS pathway: Role of a miR-155/eNOS axis in preeclampsia

(2017) Joohwan Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial DysfunctionNovelty and Significance

(2017) Kenji Onda et al.   HYPERTENSION

Sildenafil During PregnancyNovelty and Significance

(2017) Nina D. Paauw et al.   HYPERTENSION

Treatment of preeclampsia with hydroxychloroquine: a review

(2017) Rahana Abd Rahman et al.   Journal of Maternal-Fetal & Neonatal Medicine

Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia

(2017) Daniel L. Rolnik et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early- and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn

(2017) Emilie M. Herzog et al.   PLACENTA

HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) Protocol: A Multinational Randomized Controlled Trial of Hydroxychloroquine versus Placebo in Addition to Standard Treatment in Pregnant Women with Antiphospholipid Syndrome or Antibodies

(2017) Karen Schreiber et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Preeclampsia: A review of the pathogenesis and possible management strategies based on its pathophysiological derangements

(2017) Amel A.F. El-Sayed   Taiwanese Journal of Obstetrics & Gynecology

Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction

(2016) Fiona C. Brownfoot et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The impact of hydroxychloroquine treatment on pregnancy outcome in women with antiphospholipid antibodies

(2016) S. Sciascia et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The Prevalence of Hydroxychloroquine Retinopathy and Toxic Dosing, and the Role of the Ophthalmologist in Reducing Both

(2016) David J. Browning   AMERICAN JOURNAL OF OPHTHALMOLOGY

Hydroxychloroquine inhibits proinflammatory signalling pathways by targeting endosomal NADPH oxidase

(2016) Nadine Müller-Calleja et al.   ANNALS OF THE RHEUMATIC DISEASES

Critical review of the current recommendations for the treatment of systemic inflammatory rheumatic diseases during pregnancy and lactation

(2016) Roger A. Levy et al.   AUTOIMMUNITY REVIEWS

Sildenafil in Pregnancy: A Systematic Review of Maternal Tolerance and Obstetric and Perinatal Outcomes

(2016) Liam Dunn et al.   FETAL DIAGNOSIS AND THERAPY

Sildenafil Treatment Ameliorates the Maternal Syndrome of Preeclampsia and Rescues Fetal Growth in the Dahl Salt–Sensitive Rat

(2016) Ellen E. Gillis et al.   HYPERTENSION

Placental Growth Factor Administration Abolishes Placental Ischemia-Induced HypertensionNovelty and Significance

(2016) Frank T. Spradley et al.   HYPERTENSION

The risks of statin use in pregnancy: A systematic review

(2016) Dean G. Karalis et al.   Journal of Clinical Lipidology

Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia

(2016) Harald Zeisler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of simvastatin, rosuvastatin and pravastatin on soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG) secretion from human umbilical vein endothelial cells, primary trophoblast cells and placenta

(2016) Fiona C. Brownfoot et al.   BMC Pregnancy and Childbirth

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

(2016) Emily Bartsch et al.   BMJ-British Medical Journal

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

(2016) Emily Bartsch et al.   BMJ-British Medical Journal

The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: Data from a European multicenter retrospective study

(2015) Arsène Mekinian et al.   AUTOIMMUNITY REVIEWS

Diagnosis and Treatment of Hypertensive Pregnancy Disorders. Guideline of DGGG (S1-Level, AWMF Registry No. 015/018, December 2013)

(2015) H. Stepan et al.   GEBURTSHILFE UND FRAUENHEILKUNDE

Preeclampsia and Pregnancy-Related Hypertensive Disorders

(2015) S. Ananth Karumanchi et al.   HYPERTENSION

Removal of Soluble Fms-Like Tyrosine Kinase-1 by Dextran Sulfate Apheresis in Preeclampsia

(2015) R. Thadhani et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort study

(2015) M Leroux et al.   LUPUS

Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1

(2015) C. Li et al.   PLACENTA

Therapy and pharmacological properties of hydroxychloroquine and chloroquine in treatment of systemic lupus erythematosus, rheumatoid arthritis and related diseases

(2015) K. D. Rainsford et al.   INFLAMMOPHARMACOLOGY

Hypertensive disease of pregnancy and maternal mortality

(2013) Jamie O. Lo et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Early Administration of Low-Dose Aspirin for the Prevention of Preterm and Term Preeclampsia: A Systematic Review and Meta-Analysis

(2012) Stéphanie Roberge et al.   FETAL DIAGNOSIS AND THERAPY

Hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis and its safety in pregnancy

(2011) Crispin Abarientos et al.   Expert Opinion On Drug Safety

A Critical Review of Early-Onset and Late-Onset Preeclampsia

(2011) Dahlia Raymond et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Rheumatoid arthritis and pregnancy: evolution of disease activity and pathophysiological considerations for drug use

(2011) J. M. W. Hazes et al.   RHEUMATOLOGY

Role of nitric oxide and reactive oxygen species in the pathogenesis of preeclampsia

(2010) Keiichi Matsubara et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Prevention of Preeclampsia and Intrauterine Growth Restriction With Aspirin Started in Early Pregnancy

(2010) Emmanuel Bujold et al.   OBSTETRICS AND GYNECOLOGY

Placental Origins of Preeclampsia

(2008) Berthold Huppertz   HYPERTENSION