Targeting Wnt/β‐catenin by anthelmintic drug niclosamide overcomes paclitaxel resistance in esophageal cancer

Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy

(2019) Jiangbo Wang et al.   BIOCHEMICAL JOURNAL

Wnt signaling induces radioresistance through upregulating HMGB1 in esophageal squamous cell carcinoma

(2018) Yuanyuan Zhao et al.   Cell Death & Disease

WNT and NOTCH signaling pathways as activators for epidermal growth factor receptor in esophageal squamous cell carcinoma

(2018) Mohammad Reza Abbaszadegan et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas

(2017) De-Chen Lin et al.   GUT

Anthelmintic drug niclosamide enhances the sensitivity of chronic myeloid leukemia cells to dasatinib through inhibiting Erk/Mnk1/eIF4E pathway

(2016) Zhong Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Niclosamide as a Novel Anticancer Agent for Adrenocortical Carcinoma

(2016) K. Satoh et al.   CLINICAL CANCER RESEARCH

Combined niclosamide with cisplatin inhibits epithelial-mesenchymal transition and tumor growth in cisplatin-resistant triple-negative breast cancer

(2016) Junjun Liu et al.   TUMOR BIOLOGY

Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer

(2016) Chengfei Liu et al.   Oncotarget

Correlation of Wnt and NOTCH pathways in esophageal squamous cell carcinoma

(2016) Meysam Moghbeli et al.   Journal of Cell Communication and Signaling

Niclosamide suppresses renal cell carcinoma by inhibiting Wnt/β-catenin and inducing mitochondrial dysfunctions

(2016) Juan Zhao et al.   SpringerPlus

Wnt Signaling in Cancer Stem Cell Biology

(2016) Felipe de Sousa e Melo et al.   Cancers

Multi-targeted therapy of cancer by niclosamide: A new application for an old drug

(2014) Yonghe Li et al.   CANCER LETTERS

Niclosamide Inhibits Androgen Receptor Variants Expression and Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer

(2014) C. Liu et al.   CLINICAL CANCER RESEARCH

Carboplatin and paclitaxel as first-line treatment of unresectable or metastatic esophageal or gastric cancer

(2014) G. K. Prithviraj et al.   DISEASES OF THE ESOPHAGUS

Inhibition of Wnt/β-catenin pathway by niclosamide: A therapeutic target for ovarian cancer

(2014) Rebecca C. Arend et al.   GYNECOLOGIC ONCOLOGY

Oesophageal carcinoma

(2013) Arjun Pennathur et al.   LANCET

Drug Screening Identifies Niclosamide as an Inhibitor of Breast Cancer Stem-Like Cells

(2013) Yu-Chi Wang et al.   PLoS One

Inhibition of STAT3 by Niclosamide Synergizes with Erlotinib against Head and Neck Cancer

(2013) Rui Li et al.   PLoS One

NCATS launches drug repurposing program

(2012) Malorye Allison   NATURE BIOTECHNOLOGY

Activation of Wnt Signaling Using Lithium Chloride: Inquiry-Based Undergraduate Laboratory Exercises

(2012) Andrew William Ross et al.   Zebrafish

Antihelminth Compound Niclosamide Downregulates Wnt Signaling and Elicits Antitumor Responses in Tumors with Activating APC Mutations

(2011) T. Osada et al.   CANCER RESEARCH

Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway

(2011) Wenyan Lu et al.   PLoS One

Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production

(2011) F L Khanim et al.   Blood Cancer Journal

Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF- B Pathway and Generation of Reactive Oxygen Species

(2010) Y. Jin et al.   CANCER RESEARCH

Verification and Unmasking of Widely Used Human Esophageal Adenocarcinoma Cell Lines

(2010) Jurjen J. Boonstra et al.   JNCI-Journal of the National Cancer Institute

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

(2010) Matthew R Janes et al.   NATURE MEDICINE

Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements

(2010) Shivanni Kummar et al.   NATURE REVIEWS DRUG DISCOVERY

Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway

(2010) Xiaomei Ren et al.   ACS Medicinal Chemistry Letters

Recurrence after neoadjuvant chemoradiation and surgery for esophageal cancer: Does the pattern of recurrence differ for patients with complete response and those with partial or no response?

(2009) Robert A. Meguid et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY