Notch signaling regulates Akap12 expression and primary cilia length during renal tubule morphogenesis

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

(2018) Jihwan Park et al.   SCIENCE

Genes and molecular pathways underpinning ciliopathies

(2017) Jeremy F. Reiter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq

(2017) Lihe Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Notch signaling promotes nephrogenesis by downregulating Six2

(2016) Eunah Chung et al.   DEVELOPMENT

Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway

(2016) Laura Grisanti et al.   DEVELOPMENT

Axoneme Structure from Motile Cilia

(2016) Takashi Ishikawa   Cold Spring Harbor Perspectives in Biology

Compound heterozygous mutations inNEK8in siblings with end-stage renal disease with hepatic and cardiac anomalies

(2015) Ramakrishnan Rajagopalan et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Epithelial Cell Division: Aurora Kicks Lgl to the Cytoplasmic Curb

(2015) Yu-ichiro Nakajima et al.   CURRENT BIOLOGY

Aurora A Triggers Lgl Cortical Release during Symmetric Division to Control Planar Spindle Orientation

(2015) Cátia A. Carvalho et al.   CURRENT BIOLOGY

Aurora Kinases Phosphorylate Lgl to Induce Mitotic Spindle Orientation in Drosophila Epithelia

(2015) Graham P. Bell et al.   CURRENT BIOLOGY

Elevated AKAP12 in Paclitaxel-Resistant Serous Ovarian Cancer Cells Is Prognostic and Predictive of Poor Survival in Patients

(2015) Nicholas W. Bateman et al.   JOURNAL OF PROTEOME RESEARCH

Scaffolding during the cell cycle by A-kinase anchoring proteins

(2015) B. Han et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells

(2015) Heidi Hehnly et al.   eLife

The Extracellular Domain of Notch2 Increases Its Cell-Surface Abundance and Ligand Responsiveness during Kidney Development

(2013) Zhenyi Liu et al.   DEVELOPMENTAL CELL

Renal involvement and the role of Notch signalling in Alagille syndrome

(2013) Binita M. Kamath et al.   Nature Reviews Nephrology

Aurora A Kinase Regulates Mammary Epithelial Cell Fate by Determining Mitotic Spindle Orientation in a Notch-Dependent Manner

(2013) Joseph L. Regan et al.   Cell Reports

The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies

(2012) Junmin Pan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity

(2012) Katharina Hopp et al.   JOURNAL OF CLINICAL INVESTIGATION

Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation

(2012) J. L. Stubbs et al.   NATURE CELL BIOLOGY

Vertebrate kidney tubules elongate using a planar cell polarity–dependent, rosette-based mechanism of convergent extension

(2012) Soeren S Lienkamp et al.   NATURE GENETICS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Mammalian Kidney Development: Principles, Progress, and Projections

(2012) M. H. Little et al.   Cold Spring Harbor Perspectives in Biology

Renal anomalies in Alagille syndrome: A disease-defining feature

(2011) Binita M. Kamath et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development

(2011) Ellen J. Ezratty et al.   CELL

The fate of Notch-deficient nephrogenic progenitor cells during metanephric kidney development

(2011) Ramon G.B. Bonegio et al.   KIDNEY INTERNATIONAL

Real-Time Imaging of Notch Activation with a Luciferase Complementation-Based Reporter

(2011) M. X. G. Ilagan et al.   Science Signaling

Centrosomes and cilia in human disease

(2011) Mónica Bettencourt-Dias et al.   TRENDS IN GENETICS

Patterning a Complex Organ: Branching Morphogenesis and Nephron Segmentation in Kidney Development

(2010) Frank Costantini et al.   DEVELOPMENTAL CELL

The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis

(2010) Alejo E. Rodriguez-Fraticelli et al.   JOURNAL OF CELL BIOLOGY

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

(2010) M. Morimoto et al.   JOURNAL OF CELL SCIENCE

Reduced Notch Signaling Leads to Renal Cysts and Papillary Microadenomas

(2010) K. Surendran et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

(2010) Kelly L Arnett et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Liver and kidney disease in ciliopathies

(2009) Meral Gunay-Aygun   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage

(2009) Kameswaran Surendran et al.   DEVELOPMENTAL BIOLOGY

Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development

(2008) Akio Kobayashi et al.   Cell Stem Cell

Structure and function of mammalian cilia

(2008) Peter Satir et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway

(2008) Tiffiney R. Hartman et al.   HUMAN MOLECULAR GENETICS

Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis

(2008) Aron B. Jaffe et al.   JOURNAL OF CELL BIOLOGY

Identification of Ciliary Localization Sequences within the Third Intracellular Loop of G Protein-coupled Receptors

(2008) Nicolas F. Berbari et al.   MOLECULAR BIOLOGY OF THE CELL

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice

(2008) Milena Traykova-Brauch et al.   NATURE MEDICINE