Alzheimer's disease in the gut—Major changes in the gut of 5xFAD model mice with ApoA1 as potential key player

High density lipoprotein and its apolipoprotein-defined subspecies and risk of dementia

(2020) Manja Koch et al.   JOURNAL OF LIPID RESEARCH

Brain Aging and Gut–Brain Axis

(2019) M. Mohajeri   Nutrients

Vasoprotective Functions of High-Density Lipoproteins Relevant to Alzheimer’s Disease Are Partially Conserved in Apolipoprotein B-Depleted Plasma

(2019) Emily Button et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dopamine and Dopamine Receptors in Alzheimer's Disease: A Systematic Review and Network Meta-Analysis

(2019) Xiongfeng Pan et al.   Frontiers in Aging Neuroscience

The cholinergic activation of enteric glia is a physiological mechanism that contributes to the regulation of gastrointestinal motility

(2018) Ninotchska M Delvalle et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Unravelling HDL—Looking beyond the Cholesterol Surface to the Quality Within

(2018) Sarina Kajani et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Gut Microbiome Alterations and Inflammation-Driven Pathogenesis of Alzheimer’s Disease—a Critical Review

(2018) Marta Sochocka et al.   MOLECULAR NEUROBIOLOGY

Hirschsprung disease — integrating basic science and clinical medicine to improve outcomes

(2018) Robert O. Heuckeroth   Nature Reviews Gastroenterology & Hepatology

The Inflammatory Continuum of Traumatic Brain Injury and Alzheimer’s Disease

(2018) Olga N. Kokiko-Cochran et al.   Frontiers in Immunology

Alzheimer’s disease hypothesis and related therapies

(2018) Xiaoguang Du et al.   Translational Neurodegeneration

Changes of the Enteric Nervous System in Amyloid-β Protein Precursor Transgenic Mice Correlate with Disease Progression

(2018) Sandra Semar et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer’s Mouse Model

(2017) Carolin Brandscheid et al.   JOURNAL OF ALZHEIMERS DISEASE

Risk of Dementia in Patients with Spinal Cord Injury: A Nationwide Population-Based Cohort Study

(2017) Shih-Wei Huang et al.   JOURNAL OF NEUROTRAUMA

Intravenous treatment with human recombinant ApoA-I Milano reduces beta amyloid cerebral deposition in the APP23-transgenic mouse model of Alzheimer's disease

(2017) Sofía Fernández-de Retana et al.   NEUROBIOLOGY OF AGING

Loss of nitrergic and cholinergic neurons in the enteric nervous system of APP/PS1 transgenic mouse model

(2017) Xiaolei Han et al.   NEUROSCIENCE LETTERS

Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis

(2017) Subhash Kulkarni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinal cord injury and Alzheimer’s disease risk: a population-based, retrospective cohort study

(2017) Tian-Shin Yeh et al.   SPINAL CORD

Colonic Transit Time Is a Driven Force of the Gut Microbiota Composition and Metabolism: In Vitro Evidence

(2017) William Tottey et al.   Journal of Neurogastroenterology and Motility

Decreased serum apolipoprotein A1 levels are associated with poor survival and systemic inflammatory response in colorectal cancer

(2017) Päivi Sirniö et al.   Scientific Reports

Transnasal delivery of human A-beta peptides elicits impaired learning and memory performance in wild type mice

(2016) Kristina Endres et al.   BMC NEUROSCIENCE

Apolipoprotein A-I: the dual face of a protein

(2016) Angela Arciello et al.   FEBS LETTERS

Meta-Analysis of Transcriptome Data Related to Hippocampus Biopsies and iPSC-Derived Neuronal Cells from Alzheimer’s Disease Patients Reveals an Association with FOXA1 and FOXA2 Gene Regulatory Networks

(2016) Wasco Wruck et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased expression of ApoA1 after neuronal injury may be beneficial for healing

(2016) Mohor B. Sengupta et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia

(2016) Felix L. Yeh et al.   NEURON

Inflammogenesis of Secondary Spinal Cord Injury

(2016) M. Akhtar Anwar et al.   Frontiers in Cellular Neuroscience

Genes associated with Alzheimer's disease: an overview and current status

(2016) Mohan Giri et al.   Clinical Interventions in Aging

The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy

(2016) Urmi Sengupta et al.   EBioMedicine

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

(2015) Yaming Wang et al.   CELL

The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease

(2015) Jessica M. Collins et al.   EXPERIMENTAL NEUROLOGY

The Association Between Reduction in Inflammation and Changes in Lipoprotein Levels and HDL Cholesterol Efflux Capacity in Rheumatoid Arthritis

(2015) K. P. Liao et al.   Journal of the American Heart Association

Apolipoprotein-A1 as a Damage-Associated Molecular Patterns Protein in Osteoarthritis: Ex Vivo and In Vitro Pro-Inflammatory Properties

(2015) Dominique de Seny et al.   PLoS One

Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer’s disease

(2014) Véréna Landel et al.   Molecular Neurodegeneration

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Regulation of the Apolipoprotein Gene Cluster by a Long Noncoding RNA

(2014) Paul Halley et al.   Cell Reports

Intravenously Injected Human Apolipoprotein A‐I Rapidly Enters the Central Nervous System via the Choroid Plexus

(2014) Sophie Stukas et al.   Journal of the American Heart Association

Apolipoprotein AI and High-Density Lipoprotein Have Anti-Inflammatory Effects on Adipocytes via Cholesterol Transporters

(2013) Tomio Umemoto et al.   CIRCULATION RESEARCH

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Foxa1 and Foxa2 Are Required for the Maintenance of Dopaminergic Properties in Ventral Midbrain Neurons at Late Embryonic Stages

(2013) S. R. W. Stott et al.   JOURNAL OF NEUROSCIENCE

Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation

(2013) William A Eimer et al.   Molecular Neurodegeneration

Morin Inhibits the Early Stages of Amyloid β-Peptide Aggregation by Altering Tertiary and Quaternary Interactions to Produce “Off-Pathway” Structures

(2012) Justin A. Lemkul et al.   BIOCHEMISTRY

Activity-dependent secretion of alpha-synuclein by enteric neurons

(2012) Sébastien Paillusson et al.   JOURNAL OF NEUROCHEMISTRY

The enteric nervous system and neurogastroenterology

(2012) John B. Furness   Nature Reviews Gastroenterology & Hepatology

Plasma Apolipoprotein Levels Are Associated with Cognitive Status and Decline in a Community Cohort of Older Individuals

(2012) Fei Song et al.   PLoS One

Toxic fibrillar oligomers of amyloid-  have cross-  structure

(2012) J. C. Stroud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

(2012) Francisco Pan-Montojo et al.   Scientific Reports

How to Interpret a Functional or Motility Test - Colon Transit Study

(2012) Eun Ran Kim et al.   Journal of Neurogastroenterology and Motility

Soluble Aβ oligomer production and toxicity

(2011) Megan E. Larson et al.   JOURNAL OF NEUROCHEMISTRY

Gut feelings: the emerging biology of gut–brain communication

(2011) Emeran A. Mayer   NATURE REVIEWS NEUROSCIENCE

Revisiting the role of acetylcholinesterase in Alzheimer’s disease: cross-talk with P-tau and β-amyloid

(2011) María-Salud García-Ayllón   Frontiers in Molecular Neuroscience

Apolipoproteins in the brain: implications for neurological and psychiatric disorders

(2010) David A Elliott et al.   Clinical Lipidology

Amyloid oligomers: formation and toxicity of Aβ oligomers

(2010) Masafumi Sakono et al.   FEBS Journal

Apolipoprotein A-I Deficiency Increases Cerebral Amyloid Angiopathy and Cognitive Deficits in APP/PS1ΔE9 Mice

(2010) Iliya Lefterov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of Human Apolipoprotein A-I Preserves Cognitive Function and Attenuates Neuroinflammation and Cerebral Amyloid Angiopathy in a Mouse Model of Alzheimer Disease

(2010) Terry L. Lewis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Routine colonic biopsies as a new tool to study the enteric nervous system in living patients

(2009) t. lebouvier et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans

(2008) I Wessler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mid- and Late-Life Diabetes in Relation to the Risk of Dementia: A Population-Based Twin Study

(2008) W. Xu et al.   DIABETES

Human apolipoprotein A–I binds amyloid-β and prevents Aβ-induced neurotoxicity

(2008) Andréa C. Paula-Lima et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Up-regulation of reverse cholesterol transport key players and rescue from global inflammation by ApoA-IMilano

(2008) Giovanni Cimmino et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model

(2008) Ryoichi Kimura et al.   NEUROBIOLOGY OF DISEASE

Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: Autonomic pathway implicated in Parkinson's disease?

(2008) R.J. Phillips et al.   NEUROSCIENCE