Hydrogen sulfide attenuates renal fibrosis by inducing TET‐dependent DNA demethylation on Klotho promoter

Low Plasma Hydrogen Sulfide Is Associated with Impaired Renal Function and Cardiac Dysfunction

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Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies

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High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis

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Tubule-Derived Wnts Are Required for Fibroblast Activation and Kidney Fibrosis

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Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury–to–chronic kidney disease progression

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Rhein reverses Klotho repression via promoter demethylation and protects against kidney and bone injuries in mice with chronic kidney disease

(2017) Qin Zhang et al.   KIDNEY INTERNATIONAL

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Tumour hypoxia causes DNA hypermethylation by reducing TET activity

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Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog

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Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms

(2016) Timothy Alexander Hore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis

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OH, the Places You’ll Go! Hydroxylation, Gene Expression, and Cancer

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Krebs cycle intermediates regulate DNA and histone methylation: Epigenetic impact on the aging process

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Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

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Hydrogen sulfide upregulates KATP channel expression in vascular smooth muscle cells of spontaneously hypertensive rats

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Tet3-Mediated Hydroxymethylation of Epigenetically Silenced Genes Contributes to Bone Morphogenic Protein 7-Induced Reversal of Kidney Fibrosis

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TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma

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Loss of Klotho Contributes to Kidney Injury by Derepression of Wnt/ -Catenin Signaling

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Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy

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Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

(2013) Kathryn Blaschke et al.   NATURE

Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism

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Elevated Klotho Promoter Methylation Is Associated with Severity of Chronic Kidney Disease

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Inhibition of  -KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

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Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation

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Multigenerational epigenetic adaptation of the hepatic wound-healing response

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Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production

(2012) M. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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Methylation determines fibroblast activation and fibrogenesis in the kidney

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Klotho and aging

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Production and Actions of Hydrogen Sulfide, a Novel Gaseous Bioactive Substance, in the Kidneys

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The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance

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Epigenetics, Development, and the Kidney

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Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics

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H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

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