Characterization of a mouse model of obesity-related fibrotic cardiomyopathy that recapitulates features of human Heart Failure with Preserved Ejection Fraction

Diastolic dysfunction is more apparent in STZ-induced diabetic female mice, despite less pronounced hyperglycemia

(2018) Chanchal Chandramouli et al.   Scientific Reports

Distinct Myocardial Targets for Diabetes Therapy in Heart Failure With Preserved or Reduced Ejection Fraction

(2018) Walter J. Paulus et al.   JACC-Heart Failure

The extracellular matrix in myocardial injury, repair, and remodeling

(2017) Nikolaos G. Frangogiannis   JOURNAL OF CLINICAL INVESTIGATION

Biological Phenotypes of Heart Failure With Preserved Ejection Fraction

(2017) Gavin A. Lewis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction

(2016) Sanjiv J. Shah et al.   CIRCULATION

Smad3 Signaling Promotes Fibrosis While Preserving Cardiac and Aortic Geometry in Obese Diabetic MiceCLINICAL PERSPECTIVE

(2015) Anna Biernacka et al.   Circulation-Heart Failure

Oxytocin Treatment Prevents the Cardiomyopathy Observed in Obese Diabetic Male db/db Mice

(2015) Eric Plante et al.   ENDOCRINOLOGY

Heart failure with preserved ejection fraction: Refocusing on diastole

(2015) Antonio Abbate et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Fibroblast activation protein alpha expression identifies activated fibroblasts after myocardial infarction

(2015) Jochen Tillmanns et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities

(2014) Michele Cavalera et al.   Translational Research

Thrombospondin-1 Induction in the Diabetic Myocardium Stabilizes the Cardiac Matrix in Addition to Promoting Vascular Rarefaction Through Angiopoietin-2 Upregulation

(2013) Carlos Gonzalez-Quesada et al.   CIRCULATION RESEARCH

Systematic Characterization of Myocardial Inflammation, Repair, and Remodeling in a Mouse Model of Reperfused Myocardial Infarction

(2013) Panagiota Christia et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Cardiac Fibroblast-Dependent Extracellular Matrix Accumulation Is Associated with Diastolic Stiffness in Type 2 Diabetes

(2013) Kirk R. Hutchinson et al.   PLoS One

Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model

(2011) Jian-Xiong Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiac Inflammation Contributes to Changes in the Extracellular Matrix in Patients With Heart Failure and Normal Ejection Fraction

(2010) Dirk Westermann et al.   Circulation-Heart Failure

Myocardial lysyl oxidase regulation of cardiac remodeling in a murine model of diet-induced metabolic syndrome

(2009) Sherma Zibadi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia

(2009) E. Shen et al.   DIABETES