What ketamine can teach us about the opioid system in depression?

Opioid system is necessary but not sufficient for antidepressive actions of ketamine in rodents

(2020) Matthew E. Klein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of Combined Naltrexone and Ketamine With Depressive Symptoms in a Case series of Patients With Depression and Alcohol Use Disorder

(2019) Gihyun Yoon et al.   JAMA Psychiatry

Investigation of medical effect of multiple ketamine infusions on patients with major depressive disorder

(2019) Wei Zheng et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Results from a long-term open-label extension study of adjunctive buprenorphine/samidorphan combination in patients with major depressive disorder

(2019) Michael E. Thase et al.   NEUROPSYCHOPHARMACOLOGY

Attenuation of antidepressant and antisuicidal effects of ketamine by opioid receptor antagonism

(2019) Nolan R. Williams et al.   MOLECULAR PSYCHIATRY

The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

(2018) Samuel T. Wilkinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

Endogenous opioid system dysregulation in depression: implications for new therapeutic approaches

(2018) Marta Peciña et al.   MOLECULAR PSYCHIATRY

Mechanisms of ketamine action as an antidepressant

(2018) P Zanos et al.   MOLECULAR PSYCHIATRY

Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism

(2018) Nolan R. Williams et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Efficacy of Buprenorphine in Major Depression, Treatment-Resistant Depression and Suicidal Behavior: A Systematic Review

(2018) Gianluca Serafini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lack of Opioid System in the Antidepressant Actions of Ketamine

(2018) Kai Zhang et al.   BIOLOGICAL PSYCHIATRY

An update on ketamine and its two enantiomers as rapid-acting antidepressants

(2018) Kai Zhang et al.   Expert Review of Neurotherapeutics

A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression

(2016) Jaskaran B. Singh et al.   AMERICAN JOURNAL OF PSYCHIATRY

Single-dose infusion ketamine and non-ketamine N-methyl-d-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories

(2016) T. Kishimoto et al.   PSYCHOLOGICAL MEDICINE

It’s MORe exciting than mu: crosstalk between mu opioid receptors and glutamatergic transmission in the mesolimbic dopamine system

(2014) Elena H. Chartoff et al.   Frontiers in Pharmacology

The Mu-Opioid Receptor and the NMDA Receptor Associate in PAG Neurons: Implications in Pain Control

(2011) María Rodríguez-Muñoz et al.   NEUROPSYCHOPHARMACOLOGY

Opiates as Antidepressants

(2009) Esther Berrocoso et al.   CURRENT PHARMACEUTICAL DESIGN

Ultrastructural relationship between N-methyl-d-aspartate-NR1 receptor subunit and mu-opioid receptor in the mouse central nucleus of the amygdala

(2009) M.J. Glass et al.   NEUROSCIENCE