New insights into the mechanisms behind mechanical itch

Identification of a Spinal Circuit for Mechanical and Persistent Spontaneous Itch

(2019) Haili Pan et al.   NEURON

Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn

(2019) Tyler S. Nelson et al.   Scientific Reports

Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch

(2019) David Acton et al.   Cell Reports

Effects of Film Dressings on Itch Hypersensitivity Using Murine Dry Skin Models

(2018) T Iwanaga et al.   ACTA DERMATO-VENEREOLOGICA

The Neuropeptide Y system regulates both mechanical and histaminergic itch

(2018) Tianle Gao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

(2018) Martin Häring et al.   NATURE NEUROSCIENCE

Alloknesis and hyperknesis—mechanisms, assessment methodology, and clinical implications of itch sensitization

(2018) Hjalte Holm Andersen et al.   PAIN

Piezo2 channel–Merkel cell signaling modulates the conversion of touch to itch

(2018) Jing Feng et al.   SCIENCE

Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn

(2018) Alexander Chamessian et al.   Scientific Reports

Disinhibition of Touch-evoked Itch in a Mouse Model of Psoriasis

(2018) Kent Sakai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nonhistaminergic and mechanical itch sensitization in atopic dermatitis

(2017) H. H. Andersen et al.   PAIN

Mouse model of imiquimod-induced psoriatic itch

(2016) Kent Sakai et al.   PAIN

A combined electrophysiological and morphological study of neuropeptide Y–expressing inhibitory interneurons in the spinal dorsal horn of the mouse

(2016) Noboru Iwagaki et al.   PAIN

Touch Receptors Undergo Rapid Remodeling in Healthy Skin

(2016) Kara L. Marshall et al.   Cell Reports

Identification of a Spinal Circuit for Light Touch and Fine Motor Control

(2015) Steeve Bourane et al.   CELL

Anatomical evidence of pruriceptive trigeminothalamic and trigeminoparabrachial projection neurons in mice

(2015) Tasuku Akiyama et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Psychophysical Measurements of Itch and Nociceptive Sensations in an Experimental Model of Allergic Contact Dermatitis

(2015) Parul S. Pall et al.   JOURNAL OF PAIN

Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade

(2015) Zhen-Zhong Xu et al.   NATURE MEDICINE

The organisation of spinoparabrachial neurons in the mouse

(2015) Darren Cameron et al.   PAIN

A central role for spinal dorsal horn neurons that express neurokinin-1 receptors in chronic itch

(2015) Tasuku Akiyama et al.   PAIN

Gate control of mechanical itch by a subpopulation of spinal cord interneurons

(2015) S. Bourane et al.   SCIENCE

Hydrogen sulfide-induced itch requires activation of Cav3.2 T-type calcium channel in mice

(2015) Xue-Long Wang et al.   Scientific Reports

The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function

(2015) Amaury François et al.   Cell Reports

Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain

(2014) Lintao Qu et al.   BRAIN

Identification of Spinal Circuits Transmitting and Gating Mechanical Pain

(2014) Bo Duan et al.   CELL

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

(2014) Srdjan Maksimovic et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

The gentle touch receptors of mammalian skin

(2014) A. Zimmerman et al.   SCIENCE

Itch and Analgesia Resulting from Intrathecal Application of Morphine: Contrasting Effects on Different Populations of Trigeminothalamic Tract Neurons

(2013) H. R. Moser et al.   JOURNAL OF NEUROSCIENCE

The Sensory Neurons of Touch

(2013) Victoria E. Abraira et al.   NEURON

Neural processing of itch

(2013) Tasuku Akiyama et al.   NEUROSCIENCE

Mechanically evoked itch in humans

(2013) Miyuki Fukuoka et al.   PAIN

The Touch Dome Defines an Epidermal Niche Specialized for Mechanosensory Signaling

(2013) Yanne S. Doucet et al.   Cell Reports

Mouse Model of Touch-Evoked Itch (Alloknesis)

(2012) Tasuku Akiyama et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Pruriceptive spinothalamic tract neurons: physiological properties and projection targets in the primate

(2012) Steve Davidson et al.   JOURNAL OF NEUROPHYSIOLOGY

Neuropeptide Y receptor-expressing dorsal horn neurons: Role in nocifensive reflex and operant responses to aversive cold after CFA inflammation

(2012) L.L. Lemons et al.   NEUROSCIENCE

The Transcription Factor c-Maf Controls Touch Receptor Development and Function

(2012) H. Wende et al.   SCIENCE

Quantitative study of NPY-expressing GABAergic neurons and axons in rat spinal dorsal horn

(2010) Erika Polgár et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats

(2010) Earl E. Carstens et al.   NEUROREPORT

Neuropeptide Y receptor-expressing dorsal horn neurons: Role in nocifensive reflex responses to heat and formalin

(2008) R.G. Wiley et al.   NEUROSCIENCE