Article
Medicine, General & Internal
Tingting Du, Zhongliang Wang
Summary: Since 2019, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global public health event. Real-time reverse transcription polymerase chain reaction (RT-PCR) tests of upper respiratory tract specimens have been commonly used for confirmation of SARS-CoV-2. A retrospective analysis of patients diagnosed with coronavirus disease 2019 in a hospital in Wuhan was conducted, focusing on the pattern of results from repeated RT-PCR tests. Out of 984 hospitalized patients, 36.8% showed positive results from repeated RT-PCR tests. However, consecutive negative RT-PCR tests did not guarantee viral clearance, as some patients tested positive even after multiple negative tests.
Article
Radiology, Nuclear Medicine & Medical Imaging
Dandan Chen, Xinqing Jiang, Yong Hong, Zhihui Wen, Shuquan Wei, Guangming Peng, Xinhua Wei
Summary: In this study, chest CT was found to be valuable in diagnosing COVID-19 pneumonia, especially for patients with negative initial RT-PCR results. Most COVID-19 lesions were located in multiple lobes in both lungs, with ground-glass opacity and consolidation being the main CT features. Patients with negative initial RT-PCR results were less likely to show pulmonary consolidation on CT.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Infectious Diseases
Heta Parmar, Margaret Montovano, Padmapriya Banada, Sri Ram Pentakota, Stephanie Shiau, Zhongjie Ma, Kaheerman Saibire, Abby Chopoorian, Michael O'Shaughnessy, Mitchell Hirsch, Priyanshi Jain, Gaiane Demirdjian, Magali Karagueuzian, Thomas Robin, Michael Salvati, Bhavana Patel, David Alland, Yingda L. Xie
Summary: This study suggests a high likelihood of acute COVID-19 among RT-PCR negative patients with typical signs/symptoms, but a common omission of COVID-19 therapies among these patients.
BMC INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Assim A. Alfadda, Mohammad AlKhowaiter, Naif Alotaibi, Khalid Alayed, Musa Alzahrani, Khalifa Binkhamis, Khalid Siddiqui, Amira Youssef, Haifa Altalhi, Ibrahim Almaghlouth, Mohammed Alarifi, Saleh Albanyan, Mohammed Faraj Alosaimi, Rana Hasanato, Arthur Isnani, Hafedh Dekhil, Mohamed Rafiullah
Summary: This study found that distinctive symptoms and markers of COVID-19 are more frequent among patients who had RT-PCR positive results compared to those with negative results. Additionally, there were differences in clinical manifestations, laboratory parameters, and treatment approaches between the two groups.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Vikram Rao Bollineni, Koenraad Hans Nieboer, Seema Doring, Nico Buls, Johan de Mey
Summary: This study evaluated the clinical value of chest CT scans compared to RT-PCR in diagnosing COVID-19, finding that chest CT has high sensitivity and high negative predictive value, making it a potential alternative primary screening tool for COVID-19 in epidemic areas. Even with a negative RT-PCR result, a positive CT finding may still suggest a COVID-19 infection.
INSIGHTS INTO IMAGING
(2021)
Article
Multidisciplinary Sciences
Jean-Baptiste Lascarrou, Gwenhael Colin, Aurelie Le Thuaut, Nicolas Serck, Mickael Ohana, Bertrand Sauneuf, Guillaume Geri, Jean-Baptiste Mesland, Gaetane Ribeyre, Claire Hussenet, Anne Sophie Boureau, Thomas Gille
Summary: In a multicenter case-control study on COVID-19 patients, it was found that patients with symptoms of headache and fatigue/malaise were more likely to have a false-negative result in their first RT-PCR test. Conversely, patients with elevated platelet and C-reactive protein levels were at a higher risk of a false-negative first RT-PCR test result. This highlights the importance of evaluating strategies involving serial RT-PCR testing for COVID-19 diagnosis.
SCIENTIFIC REPORTS
(2021)
Article
Biotechnology & Applied Microbiology
Nikita Sherwani, Neha Singh, Arvind Neral, Jyoti Jaiswal, Tripti Nagaria, Onkar Khandwal
Summary: This study explores placental pathology in mothers infected with COVID-19 and finds that congenital transmission of SARS-CoV-2 appears to be rare. The protective properties of the placental barrier against viral infections from mother to newborn remain unclear, but the abundance of ACE-2 on the placental surface may contribute to adverse outcomes during pregnancy.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Public, Environmental & Occupational Health
V Caramello, A. Macciotta, A. De Salve, A. Mussa, A. M. De Leo, F. Bar, D. Panno, F. Nota, C. Y. G. Ling, F. Solitro, F. Ricceri, C. Sacerdote, A. Boccuzzi
Summary: This study aimed to compare patients who initially tested negative for COVID-19 with those who tested positive in terms of clinical presentation, laboratory results, imaging findings, and prognosis. Results showed that patients with negative initial tests tended to have more comorbidities such as heart disease, immunosuppression, and diabetes, and imaging was useful in identifying them. True positive patients had a higher risk of serious complications.
Article
Immunology
Wen-Lin Su, Po-Pin Hung, Chih-Pei Lin, Li-Kuang Chen, Chou-Chin Lan, Mei-Chen Yang, Ming-Yieh Peng, You-Chen Chao
Summary: In hospitals, the use of surgical masks and closed looped ventilation systems can mitigate nosocomial infection of SARS-CoV-2, with these preventive measures resulting in no viral contamination of surfaces in negative pressure environments.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2021)
Article
Infectious Diseases
Xuejiao Liao, Yuan Guan, Tetsuya Asakawa, Zixun Lin, Qingrong Tang, Zhenghua Ma, Shuting Wu, Xiaobin Wang, Jingke Dong, Liping Zhang, Jiayu Deng, Zhonghui Liao, Sumei Yang, Cheng Wang, Shuo Song, Hongyang Yi, Song Wu, Hongzhou Lu
Summary: The purpose of this study was to review clinical data and formulate recommendations for using saline as a rinse to reduce re-positive COVID-19 cases. The results showed that nasal douche treatment can shorten the time for virus nucleic acid to turn negative, thereby reducing the occurrence of re-positive cases.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Microbiology
Rifat Tasnim Juthi, Saiful Arefeen Sazed, Md Fahad Zamil, Mohammad Shafiul Alam
Summary: This study evaluated and compared the performance of three commercially available COVID-19 RT-PCR kits, with the Aridia (R) COVID-19 Real-Time PCR Test showing the best performance among them. However, the Novel Coronavirus (2019-nCoV) Nucleic Acid Detection Kit performed the worst among the three kits.
Article
Medicine, General & Internal
Amir Reza Alizad-Rahvar, Safar Vafadar, Mehdi Totonchi, Mehdi Sadeghi
Summary: Group testing is essential for preventing virus spread after COVID-19 lockdown, but caution is needed due to high false-negative rates of diagnostic tests. Integrating repeats with the group testing method can increase sensitivity. A tradeoff between sensitivity and the average number of tests should be considered when choosing the best screening strategy.
FRONTIERS IN MEDICINE
(2021)
Article
Respiratory System
Gunay Rona, Meral Arifoglu, Nuray Voyvoda, Ayse Batirel
Summary: The study aimed to investigate the diagnostic value of chest CT in RT-PCR-negative patients with suspected COVID-19. Results showed that the diagnostic value of CT was not very high, and based on clinical, laboratory, and chest x-ray findings, it may be more appropriate to refer patients to CT when necessary.
CLINICAL RESPIRATORY JOURNAL
(2021)
Article
Emergency Medicine
Ioannis Skalidis, Vinh Kim Nguyen, Hugo Bothorel, Lauriane Poli, Rui Ribeiro Da Costa, Alain Bigin Younossian, Nicole Petriccioli, Omar Kherad
Summary: Chest CT demonstrates promising sensitivity for diagnosing COVID-19, especially in patients over 65. However, CT did not substantially modify the estimated probability of COVID-19 infection in a significant proportion of patients. The utility of CT as an emergency department triage tool requires further analysis.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Infectious Diseases
Mengtian Li, Jiachen Li, Ke Wang, Lei M. Li
Summary: This study developed a deconvolution method to reconstruct COVID-19 infection incidences from daily PCR tests and applied it to epidemic data sets in Beijing and Wuxi. By estimating the delay function, the method successfully detected associated infection events and identified incidence increases, providing new insights for prevention and control strategies.
BMC INFECTIOUS DISEASES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hila Tal Tamir, Dana Stav, Yitzhac Hadad, Rivka Kessner
Summary: This study aimed to characterize thyroid nodules seen on Spectral Detector computed tomography (SDCT) and compare them with their Thyroid Imaging Reporting and Data System (TI-RADS) category on Ultrasound (US). The results showed that the spectral results of SDCT can assist in differentiating thyroid nodules of different risk levels.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Volha Nizhnikava, Ursula Reiter, Gabor Kovacs, Clemens Reiter, Corina Kraeuter, Horst Olschewski, Michael Fuchsjaeger, Gert Reiter
Summary: The purpose of this study was to investigate the associations between cardiac magnetic resonance feature-tracking-derived myocardial strain parameters and volumetric function and hemodynamic parameters in patients with pulmonary hypertension. The results showed that impairment of myocardial strains was more strongly associated with alterations in ventricular function parameters than elevated pulmonary arterial pressure, limiting the diagnostic information of myocardial strain parameters in pulmonary hypertension.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ling Qian, Rui-lin Quan, Xiao-xi Chen, Yang-yi Lin, Xiao-li Jing, Qing Gu, Chang-ming Xiong, Jian-guo He, Ai-hua Zhi
Summary: The purpose of this study was to investigate the imaging characteristics and prognostic factors for the long-term survival of Behcet's disease (BD) with arterial involvement. The results showed that arterial lesions associated with BD usually involve multiple arteries and manifest differently in different types of arteries. Cardiac involvement and pulmonary artery aneurysm/dilation were independent prognostic factors for the survival of BD patients with arterial involvement.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Yong Xie, Jian Wang, Yinghua Zou
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daria Kifjak, Maximilian Hochmair, Daniel Sobotka, Alexander R. Haug, Raphael Ambros, Florian Prayer, Benedikt H. Heidinger, Sebastian Roehrich, Ruxandra-Iulia Milos, Wolfgang Wadsak, Thorsten Fuereder, Dagmar Krenbek, Andreas Fazekas, Michael Meilinger, Marius E. Mayerhoefer, Georg Langs, Christian Herold, Helmut Prosch, Lucian Beer
Summary: The ability of pretreatment PET parameters and peripheral blood biomarkers to predict PFS and OS in NSCLC patients treated with ICIT was assessed. The study found that MTV and the number of SOI were independent risk factors for progression and overall survival, and the combination of these factors improved risk stratification.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Theresa Sophie Patzer, Jan-Peter Grunz, Henner Huflage, Jan-Lucca Hennes, Pauline Pannenbecker, Philipp Gruschwitz, Saif Afat, Judith Herrmann, Thorsten Alexander Bley, Andreas Steven Kunz
Summary: This study investigated the potential of tin prefiltration and virtual monoenergetic imaging (VMI) in suppressing metal artifacts in high-resolution CT images of the lower extremities. The results showed that VMI reconstructions had better artifact reduction compared to T3D. VMI110keV had the least image noise. In terms of image quality, interpretability of bone-metal interface, and overall image quality, VMI110keV performed the best.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yue Li, Huan Zhang, Lei Yue, Caixia Fu, Robert Grimm, Wenhua Li, Weijian Guo, Tong Tong
Summary: This study evaluated and compared the diagnostic value of diffusion-related texture analysis parameters from different magnetic resonance diffusion models in predicting the clinical response to chemotherapy in patients with colorectal liver metastases. Among the models, DKI-derived parameters showed the best performance for early prediction, followed by IVIM-derived parameters and DWI baseline features.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Wang, ShiXiong Zhang, Jun Xin
Summary: This study aimed to determine if sex differences in abdominal visceral fat composition and metabolism can help predict the prognosis of DLBCL patients. The results showed that females with certain fat composition and metabolism characteristics had worse progression-free survival, while no significant differences were found in males with DLBCL.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ping Wu, Lan Wu, Jing Ou, Jin-ming Cao, Mao-yong Fu, Tian-wu Chen, Erika Ouchi, Jiani Hu
Summary: This study aimed to develop CT radiomics models to preoperatively identify lymph node (LN) status in resectable esophageal squamous cell carcinoma (ESCC) patients. The results showed that the combined model, integrating ESCC and LN radiomics features with clinical features, had the highest predictive ability among the three models. The combined model's predictive ability was validated in both the test and external validation cohorts.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)