One-Pot Two-Step Synthesis of Isochromene-Fused CF3 -Substituted Pyrazoles

Regioselective Synthesis of 3-Trifluoromethylpyrazole by Coupling of Aldehydes, Sulfonyl Hydrazides, and 2-Bromo-3,3,3-trifluoropropene

(2020) Chuanle Zhu et al.   ORGANIC LETTERS

Cycloaddition of Trifluoroacetaldehyde N-Triftosylhydrazone (TFHZ-Tfs) with Alkynes for Synthesizing 3-Trifluoromethylpyrazoles

(2020) Hongwei Wang et al.   ORGANIC LETTERS

Oxidative Ring-Opening of 1H -Pyrazol-5-amines and Its Application in Constructing Pyrazolo-Pyrrolo-Pyrazine Scaffolds by Domino Cyclization

(2020) Lei Pan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Preparation of 1,5-Dihydropyrazolo[3′,4′:5,6]pyrano[3,4-b]pyridines via a Microwave-Assisted, Palladium-Catalyzed Regioselective C–H Heteroarylation of Electron-Rich Pyrazoles

(2019) Aaron T. Garrison et al.   JOURNAL OF ORGANIC CHEMISTRY

Reactivity of 5-aminopyrazoles bearing a cyclopropyl group at C3-position in palladium-catalyzed direct C4-arylation

(2018) Ameni Sidhom et al.   CATALYSIS COMMUNICATIONS

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Review: biologically active pyrazole derivatives

(2017) Anam Ansari et al.   NEW JOURNAL OF CHEMISTRY

Copper-Mediated Domino Cyclization/Trifluoromethylation/Deprotection with TMSCF3: Synthesis of 4-(Trifluoromethyl)pyrazoles

(2017) Quande Wang et al.   ORGANIC LETTERS

Regioselective palladium-catalyzed C H arylation of 4-alkoxy and 4-thioalkyl pyrazoles

(2017) William F. Vernier et al.   TETRAHEDRON LETTERS

Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis

(2016) Vassilios Myrianthopoulos et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 3-(Trifluoromethyl)pyrazoles and Polysubstituted Pyrazoles by atBuOK-Mediated Intramolecular Cycli­zation

(2015) Jia-Jie Wen et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Selective Incorporation of Fluorine in Pyrazoles

(2015) Joseph C. Sloop et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Trifluoromethylpyrazoles as anti-inflammatory and antibacterial agents: A review

(2015) Kamalneet Kaur et al.   JOURNAL OF FLUORINE CHEMISTRY

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Regioselective synthesis and through-space 13C–19F spin–spin coupling NMR of new tetracyclic 3-(trifluoromethyl)-spiro(chromen[4,3-c]pyrazole-4,1′-cycloalkanes)

(2014) Helio G. Bonacorso et al.   JOURNAL OF FLUORINE CHEMISTRY

Co(I) catalyzed yne–ene–yne [2+2+2] cycloaddition: synthesis of highly strained pentacyclic bis-lactones. A new access to tetraaryl N-hydroxyphthalimides

(2014) Jérôme Michaux et al.   TETRAHEDRON LETTERS

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

(2011) Santos Fustero et al.   CHEMICAL REVIEWS

Synthesis of 6-Hydroxyisochromenes and 6-Hydroxyisocoumarins from 3-Ethoxycyclohex-2-en-1-one

(2011) George Majetich et al.   HETEROCYCLES

The pharmacokinetics of mavacoxib, a long-acting COX-2 inhibitor, in young adult laboratory dogs

(2010) S. R. COX et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Efficient Routes to Pyrazolo[3,4-b]indoles and Pyrazolo[1,5-a]benzimidazoles via Palladium- and Copper-Catalyzed Intramolecular C−C and C−N Bond Formation†

(2009) Sarvesh Kumar et al.   JOURNAL OF ORGANIC CHEMISTRY

Pancratium canarienseas an Important Source of Amaryllidaceae Alkaloids

(2008) Juan C. Cedrón et al.   JOURNAL OF NATURAL PRODUCTS

Structure–activity relationship and pharmacokinetic profile of 5-ketopyrazole factor Xa inhibitors

(2007) Jeffrey G. Varnes et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS