Article
Geosciences, Multidisciplinary
Zhuang Guo, Chen Li, Yang Li, Yuanyun Wen, Kairui Tai, Xiongyao Li, Jianzhong Liu, Ziyuan Ouyang
Summary: Surface-correlated nanophase iron particles play an essential role in studying space weathering. The only strongly proven formation mechanism for these particles is vapor deposition, while other mechanisms remain debated. The analysis of the Chang'E-5 olivine rims suggests that subsolidus olivine decomposition may be the key factor in altering the reflectance spectrum of airless bodies.
GEOPHYSICAL RESEARCH LETTERS
(2022)
Article
Multidisciplinary Sciences
Alexander L. Greninger, Amin Addetia, Yue Tao, Amanda Adler, Xuan Qin
Summary: The emergence of bacterial small colony variants (SCVs) was found to be attributed to limited genetic mutations, with coding changes in genes associated with bacterial oxidative respiration and iron capture. Additionally, a 10.2 kb chromosomal segment deletion was confirmed in the E. hormaechei SCV isolate.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Carly R. Grant, Matthieu Amor, Hector A. Trujillo, Sunaya Krishnapura, Anthony T. Iavarone, Arash Komeili
Summary: This study identifies a new class of iron storage organelles called "ferrosomes" and demonstrates their formation and function in bacteria. It lays the foundation for further research on the formation and structure of ferrosomes in diverse microorganisms.
Article
Biology
Udita Roy, Shir Yaish, Ziva Weissman, Mariel Pinsky, Sunanda Dey, Guy Horev, Daniel Kornitzer
Summary: This study identifies two proteins, Frp1 and Frp2, which are involved in the extracellular heme uptake process and interact with CFEM hemophores. The research also explains the mechanism of action between these proteins and their evolutionary relationship with FREs.
Article
Cell Biology
Hye Kyoung Sung, Mayoorey Murugathasan, Ali A. Abdul-Sater, Gary Sweeney
Summary: Iron overload enhances cytochrome c release from depolarized mitochondria, increases reactive oxygen species (ROS) production, and induces apoptosis and cell death in L6 skeletal muscle cells. Treatment with superoxide dismutase mimetic MnTBAP or mitochondria-targeted antioxidant SKQ1 reduces ROS generation, attenuates iron-induced apoptosis and cell death. Autophagy-deficiency exacerbates iron-induced ROS production and apoptosis in L6 skeletal muscle cells.
CELL DEATH & DISEASE
(2023)
Article
Engineering, Environmental
Si-Ying Yu, Yang Shi, Chuan-Shu He, Yu-Dan Dong, Si Sun, Ru-Yan Ning, Zhao-Kun Xiong, Peng Zhou, Heng Zhang, Bo Lai
Summary: The introduction of chloride ions in the iron-based PAA system can enhance the reaction rate and improve the removal capacity for contaminants. The presence of chloride ions induces the generation and conversion of ROSs, leading to effective decontamination. The treatment with iron-based PAA can also alleviate the biological toxicity of pollutants.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Biology
Tatsuya Sato, Jason Solomon Shapiro, Hsiang-Chun Chang, Richard A. Miller, Hossein Ardehali
Summary: Iron is essential but its accumulation can be harmful. The study found that iron accumulation mainly occurs in the brain cortex of aged mice, which is associated with increased expression of hepcidin and decreased iron exporter.
Article
Medicine, General & Internal
Manuel Luque-Ramirez, Andres E. Ortiz-Flores, Maria Angeles Martinez-Garcia, Maria Insenser, Alejandra Quintero-Tobar, Sara De Lope Quinones, Elena Fernandez-Duran, Maria Lia Nattero-Chavez, Francisco Alvarez-Blasco, Hector Francisco Escobar-Morreale
Summary: Women with functional hyperandrogenism may experience impaired redox status after taking combined oral contraceptives (COC), and scheduled bloodletting to reduce iron stores does not override this impairment.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Microbiology
Changfu Li, Damin Pan, Mengyuan Li, Yao Wang, Luting Song, Danyang Yu, Yuxin Zuo, Kenan Wang, Yuqi Liu, Zhiyan Wei, Zhiqiang Lu, Lingfang Zhu, Xihui Shen
Summary: In the food-borne enteric pathogen Yersinia pseudotuberculosis, the aerobactin plays a critical role in iron acquisition and is directly repressed by the ferric uptake regulator in an iron concentration-dependent manner. It contributes to bacterial growth under iron-limited conditions and also plays important roles in biofilm formation, resistance to oxidative stress, ROS removal, and virulence of Y. pseudotuberculosis.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Yoko Hirata, Tomohiro Hashimoto, Kaori Ando, Yuji O. Kamatari, Hiroshi Takemori, Kyoji Furuta
Summary: This study identifies the structural features of N,N-dimethylaniline derivatives as potent ferroptosis inhibitors and demonstrates the localization of a specific compound, GIF-2197-r, in lysosomes through its aliphatic tertiary amine moiety.
Article
Biochemistry & Molecular Biology
Manuel Alejandro Vargas-Vargas, Alfredo Saavedra-Molina, Mariana Gomez-Barroso, Donovan Pena-Montes, Christian Cortes-Rojo, Huerta Miguel, Xochitl Trujillo, Rocio Montoya-Perez
Summary: Iron restriction can reduce oxidative damage, improve muscle function, and lipid profile control in diabetic rats.
Article
Agriculture, Multidisciplinary
Tongwen Huang, Ke Zhang, Junqiao Wang, Kaihong He, Xingtao Zhou, Shaoping Nie
Summary: This study found that quercetin can alleviate the hepatotoxicity caused by acrylamide generated in heat-treated foods. Experiments on mice showed that quercetin can reduce the oxidative stress levels induced by acrylamide and protect the liver from damage. The results demonstrated that quercetin suppressed acrylamide-induced ferroptosis by inhibiting oxidative stress-driven autophagy, leading to the mitigation of liver injury.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Cell Biology
Jongoh Shin, Kevin Rychel, Bernhard O. Palsson
Summary: Vibrio natriegens regulates natural competence through the TfoX and QstR transcription factors, involving external DNA capture and transport. By using a machine-learning approach, this study decomposes the transcriptome of Vibrio natriegens into 45 independently modulated sets of genes (iModulons), revealing the repression of two housekeeping iModulons and the activation of six iModulons, including TfoX and QstR, a novel iModulon of unknown function, and three housekeeping iModulons. Phenotypic screening confirms that loss of iModulon function reduces or eliminates competence. These findings provide the genetic basis for understanding the competency in this organism.
Article
Microbiology
Corinna Probst, Sarela Garcia-Santamarina, Jacob T. Brooks, Inge Van der Kloet, Oliver Baars, Martina Ralle, Dennis J. Thiele, J. Andrew Alspaugh
Summary: Copper homeostasis mechanisms are crucial for microbial adaptation during infection. In the opportunistic fungal pathogen Cryptococcus neoformans (Cn), the protein Cbi1/Bim1 is induced during copper limitation and plays a role in copper uptake. Our study suggests that Cbi1 is involved in regulating cell wall integrity and architecture, connecting copper homeostasis with adaptive changes within the fungal cell wall.
Review
Biochemistry & Molecular Biology
Sayantani Sinha, Joana Pereira-Reis, Amaliris Guerra, Stefano Rivella, Delfim Duarte
Summary: Iron is essential for maintaining normal hematopoiesis and erythropoiesis, but excessive iron can lead to toxic effects. Recent advances involve understanding key iron regulators and the development of new drugs for hematological disorders. Future studies will need to continue exploring the role of iron in both normal and malignant hematopoiesis.
ANTIOXIDANTS & REDOX SIGNALING
(2021)
Article
Soil Science
Xiaolei Huang, Lei Wang, Yiran Mei, Zhixin Jia, Tingliang Li, Guanghui Yu, Wei Ran
Summary: This study demonstrates that partially substituting chemical fertilizer with compost can enhance the topsoil carbon sequestration efficiency in a rice-wheat cropping system, primarily by increasing microbial biomass and Fe-bound organic carbon, and indirectly by improving microbial substrate-use efficiency.
APPLIED SOIL ECOLOGY
(2022)
Article
Soil Science
Caiqing Qin, Si-Liang Li, Guang-Hui Yu, Adrian M. Bass, Fu-Jun Yue, Sheng Xu
Summary: Soil in karst zones plays a crucial role in balancing the global carbon budget and regulating climate change. This study investigates the vertical variation of soil carbon and its response to land-use change in a typical karst region in SW China. The results highlight the dynamic nature of soil carbon in karst zones and the need to consider it in estimating carbon sink and global carbon budget.
Article
Engineering, Environmental
Wei La, Xiaokun Han, Cong-Qiang Liu, Hu Ding, Mingxuan Liu, Fusheng Sun, Siliang Li, Yunchao Lang
Summary: Coastal wetlands are an important source of methane emissions. This study investigates the factors controlling methane emissions by analyzing the pore-water geochemistry in the Beidagang wetland in Tianjin, China. The results show significant spatial and temporal variability in the geochemical profile, which is influenced by changes in sulfate concentration, temperature, and dissolved oxygen. Additionally, sulfate concentration has a strong impact on sulfate reduction pathways and methane consumption.
Article
Engineering, Environmental
Dan Wan, Fei-Fei Liu, Jiu-Bin Chen, Andreas Kappler, Yakov Kuzyakov, Cong-Qiang Liu, Guang-Hui Yu
Summary: The generation of reactive oxygen species (ROS) mediated by minerals and/or microorganisms has a significant impact on carbon and nutrient cycles at soil-water interfaces. Microorganisms primarily drive the production of hydroxyl radical (HO') by modulating iron redox transformation, rather than directly producing ROS. Certain genera, such as Geobacter, Paucimonas, Rhodocyclaceae_K82, and Desulfotomaculum, play a crucial role in HO' production.
Article
Engineering, Environmental
Ruixia Han, Zhe Wang, Jitao Lv, Zhe Zhu, Guang-Hui Yu, Gang Li, Yong-Guan Zhu
Summary: Microbially mediated iron redox processes play a significant role in biogeochemical cycles. Soil organic matter (SOM) affects these processes, but a comprehensive understanding is still lacking. This study examined the role of SOM in microbial iron reduction and hydroxyl radical production. The results show that SOM inhibits the transformation of ferrihydrite to crystalline iron oxides and affects Fe(II) and center dot OH production through different mechanisms.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Fusheng Sun, Guanghui Yu, Xingxing Han, Zhilai Chi, Yunchao Lang, Congqiang Liu
Summary: This study assessed the risk and binding mechanisms of potentially toxic metals in sediments from a coastal wetland under different water table depths using chemical extraction methods and high-resolution spectroscopy. The results showed that the water table depth fluctuated frequently in the coastal wetland, with minor enrichment of Pb and moderate enrichment of Cd. High-resolution spectroscopy revealed the importance of organic functional groups and partly inorganic compounds in the binding of Pb and Cd to surface sediments, while mineral components were the main binding agents in the bottom sediments.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Environmental Sciences
Yu Liu, Yucheng Hu, Chengxun Yu, Yuqi Gao, Zhenying Liu, Khan M. G. Mostofa, Siliang Li, Yumei Hu, Guanghui Yu
Summary: This study investigated the spatiotemporal variation of water quality parameters and optical properties of dissolved organic matter (DOM) in the Haihe River in Tianjin, China. It found that both salinity gradients and trophic state gradients have significant effects on the water body, influencing the abundance of chromophoric DOM (CDOM) and the fluorescence optical characteristics.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Environmental Sciences
Zhixin Jia, Xiaolei Huang, Lina Li, Tingliang Li, Yonghong Duan, Ning Ling, Guanghui Yu
Summary: The study investigates the roles of the 'enzyme latch' and 'Fe gate' mechanisms in regulating soil organic carbon (SOC) sequestration in a rice-wheat cropping system. The findings suggest that organic fertilization can strengthen the effects of these mechanisms and accelerate SOC sequestration in the system.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biodiversity Conservation
Huan Li, Guang-Hui Yu, Liping Hao, Yunpeng Qiu, Shuijin Hu
Summary: Soil organic carbon is crucial for sustaining terrestrial productivity and climate stability. Arbuscular mycorrhizal fungi (AMF) play a critical role in modulating soil carbon dynamics. However, it is still unknown how AMF-root associations interact with soil minerals to affect soil carbon cycling.
GLOBAL CHANGE BIOLOGY
(2023)
Article
Engineering, Environmental
Fu-Sheng Sun, Chao Ma, Guang-Hui Yu, Yakov Kuzyakov, Yun-Chao Lang, Ping-Qing Fu, Li-Jun Guo, Hui Henry Teng, Cong-Qiang Liu
Summary: The sequestration of organic carbon in wetland sediments is affected by oxygen availability. The mechanisms underlying the sequestration, particularly the co-mediation of reactive iron protection and thermodynamic limitations by the energetics of the organic carbon, are not well understood. Field surveys and remote sensing images have shown a significant decline in wetland areas in Tianjin over the past 26 years, which could be attributed to anthropogenic activities. High oxygen availability promotes reactive iron protection for organic carbon, while in anoxic environments, thermodynamic constraints limit its oxidation.
Review
Environmental Sciences
Hailiang Dong, Qiang Zeng, Yizhi Sheng, Chunmei Chen, Guanghui Yu, Andreas Kappler
Summary: Soils and sediments are important reservoirs of organic matter, and understanding the interactions between iron minerals and organic matter is crucial for carbon cycling and ecosystem functions. This review highlights the mechanisms and importance of coupled iron-carbon cycles, including the role of oxygenation of iron minerals, Fe(III) reduction, and the impact of organic matter on the redox properties of Fe minerals.
NATURE REVIEWS EARTH & ENVIRONMENT
(2023)
Article
Multidisciplinary Sciences
Tao Wen, Guang-Hui Yu, Wen-Dan Hong, Jun Yuan, Guo-Qing Niu, Peng-Hao Xie, Fu-Sheng Sun, Lao-Dong Guo, Yakov Kuzyakov, Qi-Rong Shen
Summary: The chemical composition of root exudates has contrasting effects on soil carbon release and rhizosphere microorganisms. Amino acids promote organic carbon release and alteration of bacterial communities, while carboxylic acids increase the prevalence of Actinobacteria and carbon mobilization. Sugar application reduces microbial diversity without significantly impacting soil carbon dynamics.
FUNDAMENTAL RESEARCH
(2022)
Article
Soil Science
Guang-Hui Yu, Sha Liu
Summary: The long-term application of manure fertilizer has been found to increase the concentrations of soluble aluminum and iron in soil, and potentially enhance the stability of organic carbon and nitrogen. The findings were supported by synchrotron radiation based FTIR spectromicroscopy, which showed the co-localization of manure fertilizer with secondary minerals and organic compounds.
FRONTIERS IN SOIL SCIENCE
(2022)