An integrative translational framework for chemical induced neurotoxicity – a systematic review

A systems toxicology approach to compare the heavy metal mixtures (Pb, As, MeHg) impact in neurodegenerative diseases

(2020) Venkatanaidu Karri et al.   FOOD AND CHEMICAL TOXICOLOGY

Whole rumen metagenome sequencing allows classifying and predicting feed efficiency and intake levels in cattle

(2019) Beatriz Delgado et al.   Scientific Reports

Neurotoxic effects of perfluoroalkyl acids: Neurobehavioral deficit and its molecular mechanism

(2019) Yu Wang et al.   TOXICOLOGY LETTERS

An industry perspective: A streamlined screening strategy using alternative models for chemical assessment of developmental neurotoxicity

(2019) Jinpeng Li et al.   NEUROTOXICOLOGY

Development and evaluation of a harmonized whole body physiologically based pharmacokinetic (PBPK) model for flutamide in rats and its extrapolation to humans

(2019) Raju Prasad Sharma et al.   ENVIRONMENTAL RESEARCH

Neuroinformatics and Computational Modelling as Complementary Tools for Neurotoxicology Studies

(2018) Marja-Leena Linne   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

1 H-nuclear magnetic resonance metabolomics revealing the intrinsic relationships between neurochemical alterations and neurobehavioral and neuropathological abnormalities in rats exposed to tris(2-chloroethyl)phosphate

(2018) Weiqun Yang et al.   CHEMOSPHERE

Evaluation of the early developmental neural toxicity of F-53B, as compared to PFOS, with an in vitro mouse stem cell differentiation model

(2018) Nuoya Yin et al.   CHEMOSPHERE

Tetrabromobisphenol A caused neurodevelopmental toxicity via disrupting thyroid hormones in zebrafish larvae

(2018) Biran Zhu et al.   CHEMOSPHERE

Childhood perfluoroalkyl substance exposure and executive function in children at 8 years

(2018) Ann M. Vuong et al.   ENVIRONMENT INTERNATIONAL

Determinants of prenatal exposure to polybrominated diphenyl ethers (PBDEs) among urban, minority infants born between 1998 and 2006

(2018) Whitney J. Cowell et al.   ENVIRONMENTAL POLLUTION

Bisphenol and phthalate concentrations and its determinants among pregnant women in a population-based cohort in the Netherlands, 2004–5

(2018) Elise M. Philips et al.   ENVIRONMENTAL RESEARCH

Comparing dietary and non-dietary source contribution of BPA and DEHP to prenatal exposure: A Catalonia (Spain) case study

(2018) M.A. Martínez et al.   ENVIRONMENTAL RESEARCH

TBBPA and Its Alternatives Disturb the Early Stages of Neural Development by Interfering with the NOTCH and WNT Pathways

(2018) Nuoya Yin et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Intranasal administration of tetrabromobisphenol A bis(2-hydroxyethyl ether) induces neurobehavioral changes in neonatal Sprague Dawley rats

(2018) Qian S. Liu et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity: Deepening into the molecular mechanism of neurodegenerative diseases

(2018) Venkatanaidu Karri et al.   Journal of Proteomics

Neurological responses of embryo-larval zebrafish to short-term sediment exposure to decabromodiphenylethane

(2018) Mei-qing Jin et al.   Journal of Zhejiang University-SCIENCE B

The development of a pregnancy PBPK Model for Bisphenol A and its evaluation with the available biomonitoring data

(2018) Raju Prasad Sharma et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

(2018) Ellen Fritsche et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A systems biology approach to predictive developmental neurotoxicity of a larvicide used in the prevention of Zika virus transmission

(2018) Karine Audouze et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An in vitro cytotoxic approach to assess the toxicity of heavy metals and their binary mixtures on hippocampal HT-22 cell line

(2018) Venkatanaidu Karri et al.   TOXICOLOGY LETTERS

Sensitive neurotoxicity assessment of bisphenol A using double immunocytochemistry of DCX and MAP2

(2018) Jung-Hyun Cho et al.   ARCHIVES OF PHARMACAL RESEARCH

3,3ʹ-Dichlorobiphenyl (PCB 11) promotes dendritic arborization in primary rat cortical neurons via a CREB-dependent mechanism

(2018) Sunjay Sethi et al.   ARCHIVES OF TOXICOLOGY

The Action of Di-(2-Ethylhexyl) Phthalate (DEHP) in Mouse Cerebral Cells Involves an Impairment in Aryl Hydrocarbon Receptor (AhR) Signaling

(2018) Anna K. Wójtowicz et al.   NEUROTOXICITY RESEARCH

Finding synergies for 3Rs – Toxicokinetics and read-across: Report from an EPAA partners' Forum

(2018) Charles Laroche et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC–Derived Neural 3D Cultures

(2018) Oksana Sirenko et al.   TOXICOLOGICAL SCIENCES

Toxicology for Real-Life Risk Simulation - Editorial Preface to this Special Issue

(2018) Aristidis Tsatsakis et al.   TOXICOLOGY LETTERS

Integrating data gap filling techniques: A case study predicting TEFs for neurotoxicity TEQs to facilitate the hazard assessment of polychlorinated biphenyls

(2018) Prachi Pradeep et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Prenatal phthalate biomarker concentrations and performance on the Bayley Scales of Infant Development-II in a population of young urban children

(2017) Brett T. Doherty et al.   ENVIRONMENTAL RESEARCH

Pesticides, polychlorinated biphenyls and polycyclic aromatic hydrocarbons in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a case-control study

(2017) Marco Vinceti et al.   ENVIRONMENTAL RESEARCH

The environmental pollutant BDE-209 regulates NO/cGMP signaling through activation of NMDA receptors in neurons

(2017) Jingsi Chen et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Impairment in the mesohippocampal dopamine circuit following exposure to the brominated flame retardant, HBCDD

(2017) Camille Pham-Lake et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Perfluoroalkyl substances, thyroid hormones, and neuropsychological status in older adults

(2017) Srishti Shrestha et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Prenatal phthalate, triclosan, and bisphenol A exposures and child visual-spatial abilities

(2017) Joseph M. Braun et al.   NEUROTOXICOLOGY

Prenatal environmental chemical exposures and longitudinal patterns of child neurobehavior

(2017) Joseph M. Braun et al.   NEUROTOXICOLOGY

The application of PBPK models in estimating human brain tissue manganese concentrations

(2017) Siva P. Ramoju et al.   NEUROTOXICOLOGY

The involvement of autophagy and cytoskeletal regulation in TDCIPP-induced SH-SY5Y cell differentiation

(2017) Ruiwen Li et al.   NEUROTOXICOLOGY

Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity

(2017) Anna Bal-Price et al.   NEUROTOXICOLOGY

Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells

(2017) Theodore A. Slotkin et al.   TOXICOLOGY

Developing integrated PBPK/PD coupled mechanistic pathway model (miRNA-BDNF): An approach towards system toxicology

(2017) Raju Prasad Sharma et al.   TOXICOLOGY LETTERS

Profiling of Selected Functional Metabolites in the Central Nervous System of Marine Medaka (Oryzias melastigma) for Environmental Neurotoxicological Assessments

(2016) Elva Ngai-Yu Lei et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Multiparameter toxicity assessment of novel DOPO-derived organophosphorus flame retardants

(2016) Cordula Hirsch et al.   ARCHIVES OF TOXICOLOGY

Perfluoroalkyl substances in cord blood and attention deficit/hyperactivity disorder symptoms in seven-year-old children

(2016) Guang-Wen Lien et al.   CHEMOSPHERE

Translational Epidemiology

(2016) Ravi Shah et al.   CIRCULATION RESEARCH

Translational Medicine Guide transforms drug development processes: the recent Merck experience

(2016) Hugues Dolgos et al.   DRUG DISCOVERY TODAY

Urinary biomarkers of exposure to 57 xenobiotics and its association with oxidative stress in a population in Jeddah, Saudi Arabia

(2016) Alexandros G. Asimakopoulos et al.   ENVIRONMENTAL RESEARCH

Heavy metals (Pb, Cd, As and MeHg) as risk factors for cognitive dysfunction: A general review of metal mixture mechanism in brain

(2016) Venkatanaidu Karri et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

New challenges in risk assessment of chemicals when simulating real exposure scenarios; simultaneous multi-chemicals' low dose exposure

(2016) Aristidis M. Tsatsakis et al.   FOOD AND CHEMICAL TOXICOLOGY

Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach

(2016) AM Tsatsakis et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

The Cellular and Molecular Landscapes of the Developing Human Central Nervous System

(2016) John C. Silbereis et al.   NEURON

TBBPA causes neurotoxic and the apoptotic responses in cultured mouse hippocampal neurons in vitro

(2016) Konrad A. Szychowski et al.   Pharmacological Reports

Influence of the uncertainty in the validation of PBPK models: A case-study for PFOS and PFOA

(2016) Francesc Fàbrega et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Prenatal exposure to perfluorinated chemicals and neurodevelopment in early infancy: The Hokkaido Study

(2016) Houman Goudarzi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Neurobehavioral assessment of maternal odor in developing rat pups: implications for social buffering

(2016) Syrina Al Aïn et al.   Social Neuroscience

An Extended Structure–Activity Relationship of Nondioxin-Like PCBs Evaluates and Supports Modeling Predictions and Identifies Picomolar Potency of PCB 202 Towards Ryanodine Receptors

(2016) Erika B. Holland et al.   TOXICOLOGICAL SCIENCES

Role of glutamate receptors in tetrabrominated diphenyl ether (BDE-47) neurotoxicity in mouse cerebellar granule neurons

(2016) Lucio G. Costa et al.   TOXICOLOGY LETTERS

Reliability of Neurobehavioral Assessments from Birth to Term Equivalent Age in Preterm and Term Born Infants

(2016) Abbey L. Eeles et al.   PHYSICAL & OCCUPATIONAL THERAPY IN PEDIATRICS

A Systematic Review of the Predictive Validity of Neurobehavioral Assessments During the Preterm Period

(2016) Oana Craciunoiu et al.   PHYSICAL & OCCUPATIONAL THERAPY IN PEDIATRICS

Polybrominated Diphenyl Ethers in Maternal Serum, Breast Milk, Umbilical Cord Serum, and House Dust in a South Korean Birth Panel of Mother-Neonate Pairs

(2016) Mi-Yeon Shin et al.   International Journal of Environmental Research and Public Health

Effects of perfluorooctane sulfonate and its alternatives on long-term potentiation in the hippocampus CA1 region of adult rats in vivo

(2016) Qian Zhang et al.   Toxicology Research

High content imaging quantification of multiple in vitro human neurogenesis events after neurotoxin exposure

(2016) Xian Wu et al.   BMC Pharmacology & Toxicology

Putative adverse outcome pathways relevant to neurotoxicity

(2015) Anna Bal-Price et al.   CRITICAL REVIEWS IN TOXICOLOGY

Bioconcentration and Transfer of the Organophorous Flame Retardant 1,3-Dichloro-2-propyl Phosphate Causes Thyroid Endocrine Disruption and Developmental Neurotoxicity in Zebrafish Larvae

(2015) Qiangwei Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Assessment of Bisphenol A (BPA) neurotoxicity in vitro with mouse embryonic stem cells

(2015) Nuoya Yin et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Neurotoxicity and risk assessment of brominated and alternative flame retardants

(2015) Hester S. Hendriks et al.   NEUROTOXICOLOGY AND TERATOLOGY

Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) and tris(2-chloro-2-ethyl)phosphate (TCEP)

(2015) Virginia C. Moser et al.   NEUROTOXICOLOGY AND TERATOLOGY

Translational toxicology in setting occupational exposure limits for dusts and hazard classification – a critical evaluation of a recent approach to translate dust overload findings from rats to humans

(2015) Peter Morfeld et al.   Particle and Fibre Toxicology

Development of an integrated approach for comparison of in vitro and in vivo responses to particulate matter

(2015) Dalibor Breznan et al.   Particle and Fibre Toxicology

Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward

(2015) Ruth A. Roberts et al.   TOXICOLOGICAL SCIENCES

Improving in vitro to in vivo extrapolation by incorporating toxicokinetic measurements: A case study of lindane-induced neurotoxicity

(2015) Edward L. Croom et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A comparison of the in vitro cyto- and neurotoxicity of brominated and halogen-free flame retardants: prioritization in search for safe(r) alternatives

(2014) Hester S. Hendriks et al.   ARCHIVES OF TOXICOLOGY

Effects of neonatal exposure to the flame retardant tetrabromobisphenol-A, aluminum diethylphosphinate or zinc stannate on long-term potentiation and synaptic protein levels in mice

(2014) Hester S. Hendriks et al.   ARCHIVES OF TOXICOLOGY

BDE-47 and 6-OH-BDE-47 modulate calcium homeostasis in primary fetal human neural progenitor cells via ryanodine receptor-independent mechanisms

(2014) Kathrin Gassmann et al.   ARCHIVES OF TOXICOLOGY

Computational models to predict endocrine-disrupting chemical binding with androgen or oestrogen receptors

(2014) Yingjie Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Primary neuronal-astrocytic co-culture platform for neurotoxicity assessment of di-(2-ethylhexyl) phthalate

(2014) Yang Wu et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Brain drain: the cost of neglected responsibilities in evaluating cumulative effects of environmental chemicals

(2014) Maricel V Maffini et al.   JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

The Environmental Neurotoxicant PCB 95 Promotes Synaptogenesis via Ryanodine Receptor-Dependent miR132 Upregulation

(2014) Adam Lesiak et al.   JOURNAL OF NEUROSCIENCE

Classification of phthalates based on an in vitro neurosphere assay using rat mesencephalic neural stem cells

(2014) Masami Ishido et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Multiparametric High Content Analysis for assessment of neurotoxicity in differentiated neuronal cell lines and human embryonic stem cell-derived neurons

(2014) Melinda S. Wilson et al.   NEUROTOXICOLOGY

Synergistic neurotoxicity of oxygen-glucose deprivation and tetrabromobisphenol A in vitro: role of oxidative stress

(2014) Elżbieta Ziemińska et al.   Pharmacological Reports

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)

(2014) Knut Erik Tollefsen et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

PBPK modeling for PFOS and PFOA: Validation with human experimental data

(2014) Francesc Fàbrega et al.   TOXICOLOGY LETTERS

Bisphenol A promotes dendritic morphogenesis of hippocampal neurons through estrogen receptor-mediated ERK1/2 signal pathway

(2013) Xiaohong Xu et al.   CHEMOSPHERE

In silico methods to predict drug toxicity

(2013) Alessandra Roncaglioni et al.   CURRENT OPINION IN PHARMACOLOGY

Perfluorinated Compound Levels in Cord Blood and Neurodevelopment at 2 Years of Age

(2013) Mei-Huei Chen et al.   EPIDEMIOLOGY

Brominated Flame Retardants in Breast Milk and Behavioural and Cognitive Development at 36 Months

(2013) Margaret A. Adgent et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Phthalates Induce Neurotoxicity Affecting Locomotor and Thermotactic Behaviors and AFD Neurons through Oxidative Stress in Caenorhabditis elegans

(2013) I-Ling Tseng et al.   PLoS One

A Hydroxylated Metabolite of Flame-Retardant PBDE-47 Decreases the Survival, Proliferation, and Neuronal Differentiation of Primary Cultured Adult Neural Stem Cells and Interferes with Signaling of ERK5 MAP Kinase and Neurotrophin 3

(2013) Tan Li et al.   TOXICOLOGICAL SCIENCES

Alterations to the circuitry of the frontal cortex following exposure to the polybrominated diphenyl ether mixture, DE-71

(2013) Joshua M. Bradner et al.   TOXICOLOGY

Translational toxicology: a developmental focus for integrated research strategies

(2013) Claude Hughes et al.   BMC Pharmacology & Toxicology

In vitroevaluation of gene expression changes for gonadotropin-releasing hormone 1, brain-derived neurotrophic factor and neurotrophic tyrosine kinase, receptor, type 2, in response to bisphenol A treatment

(2012) Katsuhiko Warita et al.   CONGENITAL ANOMALIES

Quantitativein vitrotoin vivoextrapolation of cell-based toxicity assay results

(2012) Miyoung Yoon et al.   CRITICAL REVIEWS IN TOXICOLOGY

Insight into the neuroproteomics effects of the food-contaminant non-dioxin like polychlorinated biphenyls

(2012) Laura Brunelli et al.   Journal of Proteomics

Does developmental exposure to perflurooctanoic acid (PFOA) induce immunopathologies commonly observed in neurodevelopmental disorders?

(2012) Qing Hu et al.   NEUROTOXICOLOGY

Evaluating the neurotoxic effects of lactational exposure to persistent organic pollutants (POPs) in Spanish children

(2012) Mireia Gascon et al.   NEUROTOXICOLOGY

Some Commonly Used Brominated Flame Retardants Cause Ca2+-ATPase Inhibition, Beta-Amyloid Peptide Release and Apoptosis in SH-SY5Y Neuronal Cells

(2012) Fawaz Al-Mousa et al.   PLoS One

Multiple Novel Modes of Action Involved in the In Vitro Neurotoxic Effects of Tetrabromobisphenol-A

(2012) Hester S. Hendriks et al.   TOXICOLOGICAL SCIENCES

Differential Effects of 20 Non-Dioxin-Like PCBs on Basal and Depolarization-Evoked Intracellular Calcium Levels in PC12 Cells

(2012) W. T. Langeveld et al.   TOXICOLOGICAL SCIENCES

The role of the IRE1 pathway in PBDE-47-induced toxicity in human neuroblastoma SH-SY5Y cells in vitro

(2012) Chunyang Jiang et al.   TOXICOLOGY LETTERS

The acceptance of in silico models for REACH: Requirements, barriers, and perspectives

(2011) Emilio Benfenati et al.   Chemistry Central Journal

Multivariate toxicity profiles and QSAR modeling of non-dioxin-like PCBs – An investigation of in vitro screening data from ultra-pure congeners

(2011) Mia Stenberg et al.   CHEMOSPHERE

Neurochemical changes following a single dose of polybrominated diphenyl ether 47 in mice

(2011) Jillian R. Gee et al.   DRUG AND CHEMICAL TOXICOLOGY

Translational Research to Develop a Human PBPK Models Tool Kit—Volatile Organic Compounds (VOCs)

(2011) M. Moiz Mumtaz et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Improving the efficacy of translational medicine by optimally integrating health care, academia and industry

(2011) Stefan R Bornstein et al.   NATURE MEDICINE

Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo

(2011) Kyung Ho Kim et al.   NEUROTOXICOLOGY

Non–Dioxin-like Polychlorinated Biphenyls Interfere with Neuronal Differentiation of Embryonic Neural Stem Cells

(2011) Roshan Tofighi et al.   TOXICOLOGICAL SCIENCES

Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells

(2011) Laura V. Dishaw et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Possible mechanism of perfluorooctane sulfonate and perfluorooctanoate on the release of calcium ion from calcium stores in primary cultures of rat hippocampal neurons

(2011) Xiaohui Liu et al.   TOXICOLOGY IN VITRO

An Integrative Systems Biology Approach to Understanding Pulmonary Diseases

(2010) Charles Auffray et al.   CHEST

Quantitative structure-activity relationship (QSAR) studies for predicting activation of the ryanodine receptor type 1 channel complex (RyR1) by polychlorinated biphenyl (PCB) congeners

(2010) Sierra Rayne et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING

Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. mechanisms involved

(2010) J. Boix et al.   NEUROSCIENCE

Behavioral toxicology in the 21st century: Challenges and opportunities for behavioral scientists

(2010) Philip J. Bushnell et al.   NEUROTOXICOLOGY AND TERATOLOGY

Toxicoepigenetic Alteration of the Kidney Injury Molecule 1 Gene in Gentamicin-Exposed Rat Kidney

(2010) Feifei Chen et al.   TOXICOLOGICAL SCIENCES

Changes in mitogen-activated protein kinase in cerebellar granule neurons by polybrominated diphenyl ethers and polychlorinated biphenyls☆☆☆

(2010) Chun-Yang Fan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mono-(2-ethylhexyl) phthalate impairs neurodevelopment: Inhibition of proliferation and promotion of differentiation in PC12 cells

(2010) Tian Chen et al.   TOXICOLOGY LETTERS

Translational research: understanding the continuum from bench to bedside

(2010) Brian C. Drolet et al.   Translational Research

Polybrominated Diphenyl Ethers Induce Developmental Neurotoxicity in a Human in Vitro Model: Evidence for Endocrine Disruption

(2009) Timm Schreiber et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants

(2009) Frode Fonnum et al.   JOURNAL OF NEUROCHEMISTRY

Neuroscience in the era of functional genomics and systems biology

(2009) Daniel H. Geschwind et al.   NATURE

Polychlorinated Biphenyls PCB 153 and PCB 126 Impair the Glutamate–Nitric Oxide–cGMP Pathway in Cerebellar Neurons in Culture by Different Mechanisms

(2009) Marta Llansola et al.   NEUROTOXICITY RESEARCH

Effects of Decabrominated Diphenyl Ether (PBDE 209) Exposure at Different Developmental Periods on Synaptic Plasticity in the Dentate Gyrus of Adult Rats In Vivo

(2009) Tairan Xing et al.   TOXICOLOGICAL SCIENCES

Are In Vitro Tests Suitable for Regulatory Use?

(2009) Thomas Hartung et al.   TOXICOLOGICAL SCIENCES

Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells

(2009) Sara Tagliaferri et al.   TOXICOLOGY IN VITRO

Developmental Neurotoxicity of Perfluorinated Chemicals Modeled in Vitro

(2008) Theodore A. Slotkin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Polychlorinated biphenyl-induced oxidative stress in organotypic co-cultures: Experimental dopamine depletion prevents reductions in GABA

(2008) G LYNG   NEUROTOXICOLOGY

Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71

(2008) Gennaro Giordano et al.   NEUROTOXICOLOGY

Hexabromocyclododecane Inhibits Depolarization-Induced Increase in Intracellular Calcium Levels and Neurotransmitter Release in PC12 Cells

(2008) Milou M. L. Dingemans et al.   TOXICOLOGICAL SCIENCES

Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels

(2008) Gennaro Giordano et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Role of N-methyl-D-aspartate receptors in polychlorinated biphenyl mediated neurotoxicity

(2008) Leopold Tchapda Ndountse et al.   TOXICOLOGY LETTERS

Translational Systems Biology of Inflammation

(2008) Yoram Vodovotz et al.   PLoS Computational Biology

Oxidative Stress and Neurotoxicity

(2007) Lawrence M. Sayre et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Neurobehavioral assessment of rats exposed to low doses of PCB126 and methyl mercury during development

(2007) Annabella Vitalone et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons

(2007) Hoa H. Le et al.   TOXICOLOGY LETTERS