Review
Biotechnology & Applied Microbiology
Nabeelah Bibi Sadeer, Gokhan Zengin, Mohamad Fawzi Mahomoodally
Summary: Mangrove plants are ecologically important and produce unique compounds in extreme conditions. Mangrove microbes have the potential for vaccine development and the synthesis of nanoparticles. Mangrove plants also contain bioactive compounds with pharmaceutical applications.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2023)
Article
Acoustics
Sasadhar Majhi
Summary: Total synthesis is a method for preparing complex natural products from simple materials, which plays a crucial role in confirming complex structures and preparing rare bioactive substances. The use of ultrasound as a non-polluting energy source in the synthesis of bioactive natural products highlights its potential in sustainable and pharmaceutical chemistry.
ULTRASONICS SONOCHEMISTRY
(2021)
Review
Chemistry, Medicinal
Giovanna Romano, Mariana Almeida, Ana Varela Coelho, Adele Cutignano, Luis G. Goncalves, Espen Hansen, Denis Khnykin, Tali Mass, Andreja Ramsak, Miguel S. Rocha, Tiago H. Silva, Michela Sugni, Loriano Ballarin, Anne-Marie Geneviere
Summary: Aquatic invertebrates are an important source of biomaterials and bioactive natural products. This review analyzes the literature from 2010 to 2019 on natural products from marine invertebrate phyla. It also discusses the role of symbiotic microorganisms and macro-organisms in the synthesis of secondary metabolites, as well as the application of omics tools in understanding the biosynthesis of these compounds. The study and utilization of aquatic invertebrate stem cells may hold promise for improving the biodiscovery pipeline.
Article
Microbiology
Hai Gao, Yanan Wang, Qiao Luo, Liyuan Yang, Xingxing He, Jun Wu, Konthorn Kachanuban, Pongthep Wilaipun, Weiming Zhu, Yi Wang
Summary: This study isolated 237 acid-tolerant fungi from Thai mangrove sediments, with Penicillium, Aspergillus, and Talaromyces as the dominant genera; 95% of the isolates could grow under extremely acidic conditions; Acid stress may activate silent gene clusters to expand the diversity of secondary metabolites.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Chemistry, Medicinal
Bo Peng, Jian Cai, Zimin Xiao, Manli Liu, Xinlong Li, Bin Yang, Wei Fang, Yi-You Huang, Chunmei Chen, Xuefeng Zhou, Huaming Tao
Summary: A chemical investigation of two fungi strains derived from the Beibu Gulf led to the discovery of 23 natural products, including two polyketide derivatives and three hydroxyphenylacetic acid derivatives. The structures were determined through NMR and MS analyses, and the absolute configurations were established through ECD calculation. The compounds exhibited various bioactivities, including antifungal and cytotoxic effects, as well as inhibition of PDE4 and AChE.
Article
Soil Science
Huang Yu, Xingyu Liu, Chao Yang, Yisheng Peng, Xiaoli Yu, Hang Gu, Xiafei Zheng, Cheng Wang, Fanshu Xiao, Longfei Shu, Zhili He, Bo Wu, Qingyun Yan
Summary: Nitrogen is a critical nutrient for mangrove ecosystems, and this study found significant positive correlations between the richness/diversity of diazotrophs and AMF community in the rhizosphere. Positive co-occurrence between AMF and diazotrophs may promote nitrogen fixation efficiency in mangrove ecosystems. Keystone AMF taxa were identified as important predictors of biological nitrogen fixation in the rhizosphere, and factors such as alpha-diversity of AMF and diazotrophs communities, N-related enzymes, and sediment nutrition components were found to drive this process.
SOIL BIOLOGY & BIOCHEMISTRY
(2021)
Article
Agricultural Engineering
Paulina Leite, Isabel Belo, Jose Manuel Salgado
Summary: The co-processing of wastes from different agro-food industries through solid-state fermentation can produce lignocellulolytic enzymes and antioxidant compounds, achieving the valorization of these wastes. The fermentation of waste mixtures resulted in high enzymatic and antioxidant activities, allowing for the co-management of agro-industrial wastes.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Polymer Science
Adrian Krzysztof Antosik, Urszula Kowalska, Magdalena Stobinska, Paulina Dzieciol, Magdalena Pieczykolan, Katarzyna Kozlowska, Artur Bartkowiak
Summary: The study showed that adding 5% oregano oil and 5% cedar oil in PP matrix resulted in the best antimicrobial properties. These bioactive PP films with biocidal activity can be added to packaging plastic materials like polyolefins to help prolong the shelf life of food products.
Review
Pharmacology & Pharmacy
Qinfang Zheng, Ye Wang, Shuihan Zhang
Summary: This work reviews the progress in the phytochemical and biological investigations of bioactive components from Lobelia species, highlighting the shift in research focus towards novel chemical classes and molecular mechanisms of these components.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Zhonglei Wang, Ning Wang, Liyan Yang, Xian-qing Song
Summary: This paper reviews the studies on natural products in the treatment of COVID-19, highlighting their potential applications in vitro and providing essential guidance for the development of anti-SARS-CoV-2 drugs.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Multidisciplinary Sciences
Candice L. Swift, Katherine B. Louie, Benjamin P. Bowen, Heather M. Olson, Samuel O. Purvine, Asaf Salamov, Stephen J. Mondo, Kevin Solomon, Aaron T. Wright, Trent R. Northen, Igor Grigoriev, Nancy P. Keller, Michelle A. O'Malley
Summary: Anaerobic gut fungi, as low-abundance members of the herbivore digestive tract, have been found to potentially synthesize diverse natural products, including antibiotics and antimicrobial peptides. Through a multi-omics approach, genes encoding biosynthetic enzymes for natural products were identified in four representative anaerobic gut fungal species. This suggests that these fungi could serve as a valuable source of antimicrobials and therapeutics.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Chemistry, Multidisciplinary
Magdalena Surma, Katarzyna Sznajder-Katarzynska, Wieslaw Wiczkowski, Henryk Zielinski
Summary: This study investigated the presence of PFAS in plant-based food products and found multiple PFAS compounds in cereal-based products. Perfluorooctanoic acid (PFOA) was the most frequently detected compound, while perfluorobutanoic acid (PFBA) was the predominant PFAS in cereal-based products. These compounds likely originate from soil-root-shoot interactions and the ability of PFAS to interfere with proteins. Therefore, cereal-based products should be considered in future dietary exposure assessments.
APPLIED SCIENCES-BASEL
(2022)
Review
Biochemistry & Molecular Biology
Juntai Zhu, Lixia Song, Shengnan Shen, Wanxin Fu, Yaying Zhu, Li Liu
Summary: This review focuses on Aspergillus-derived alkaloids, compounds with diverse biological activities and structural diversity.
Review
Chemistry, Medicinal
Dioni Arrieche, Jaime R. Cabrera-Pardo, Aurelio San-Martin, Hector Carrasco, Lautaro Taborga
Summary: This review summarizes the fungal natural products isolated from Antarctic and Chilean marine environments and their biological activities.
Review
Microbiology
Meirong Ren, Shuhua Jiang, Yanyan Wang, Xinhua Pan, Feng Pan, Xinli Wei
Summary: Lichen natural products are a valuable resource for drug discovery, yet their utilization has been limited due to slow growth, low biomass availability, and technical challenges in cultivation. To overcome these challenges, the OSMAC strategy has been developed to activate silent or cryptic biosynthetic gene clusters and exploit lichen compounds for industrial applications. Additionally, advancements in molecular network techniques and genetic tools provide opportunities for mining, modifying, and producing lichen metabolites.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Yudong Cao, Bin Chen, Haibin Zhong, Liyuan Pei, Guanglei Liu, Zhenglong Xu, Jianfeng Shen, Mingxin Ye
Summary: This study reports the design of a flexible sensor using Ti2C3Tx/polyurethane composites prepared by gas-liquid interface self-assembly. The sensor has a wide detection range, low-stress detection limit, high sensitivity, and fast response time, making it suitable for various applications such as wearable motion monitoring, underwater human motion detection, and monitoring of fish motion in water.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Biotechnology & Applied Microbiology
Zhe Chi, Cun-Cui Kong, Zhuang-Zhuang Wang, Zhu Wang, Guang-Lei Liu, Zhong Hu, Zhen-Ming Chi
Summary: Aureobasidium spp. can adapt to different environments and regulate substrate utilization and cell growth through multiple signaling pathways. However, the molecular mechanisms of high temperature growth and glucose derepression in some novel strains of A. melanogenum are still unclear.
BIOTECHNOLOGY ADVANCES
(2022)
Article
Engineering, Chemical
Wei Yao, Xuanyang Li, Xiaodong Zhu, Liyuan Pei, Guanglei Liu, Yang Cheng, Mason Oliver Lam Chee, Pei Dong, Jianfeng Shen, Mingxin Ye
Summary: This study proposes a new method using nano carbon black composite aerogel for stable and efficient solar desalination. The composite material with inclined channels and hydrophilic/hydrophobic interface improves evaporation efficiency, stabilizes water output, and shows salt-resistant property.
Article
Biochemistry & Molecular Biology
Cong-Yan Qi, Zhe Chi, Guang-Lei Liu, Zhen-Ming Chi
Summary: The research found that Aureobasidium melanogenum OUC and its engineered mutants can produce high molecular weight PMA, with the PMA yield of transgenic strain Crz46 increased by about twice compared to the native strain.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Multidisciplinary
Shun Guo, Wang Ding, Huihui Zhang, Weiqun Lu, Guanglei Liu, Haixia Liu, Xiaonong Cheng, Xinqing Zhao
Summary: In this study, a Ti-Nb alloy with large near-linear recoverable strain was designed to investigate the physical mechanisms responsible for high near-linear elastic deformability. The experimental results showed that the high near-linear elastic deformability of this alloy is attributed to a combined effect of large inherent elastic deformation and a reversible SIMT.
MATERIALS CHARACTERIZATION
(2022)
Review
Biochemistry & Molecular Biology
Peng Wang, Shu-Lei Jia, Guang-Lei Liu, Zhe Chi, Zhen-Ming Chi
Summary: Aureobasidium spp. are dimorphic fungi with both yeast and filamentous cells. They can synthesize various enzymes and natural products, and their genomes have been sequenced and annotated. They are considered as emerging cells for fungal biotechnology and biology.
PROCESS BIOCHEMISTRY
(2022)
Article
Biotechnology & Applied Microbiology
Zhu Wang, Mei Zhangna, Zhe Chi, Guang-Lei Liu, Zhen-Ming Chi
Summary: This study successfully produced a high yield of liamocins through gene mutation and overexpression. The overexpressed genes promoted liamocins biosynthesis and sugar transport. Massoia lactone prepared from liamocins showed promising antifungal activity.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2022)
Article
Engineering, Marine
Li Yuan, Hong-Qian Zhang, Zhe Chi, Guang-Lei Liu, Zhen-Ming Chi
Summary: In this study, it was found that stable nanemulsions loaded with Massoia lactone could be prepared using specific ingredients. The obtained nanemulsions showed high anti-fungal and free radical scavenging activities.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Materials Science, Multidisciplinary
Shun Guo, Wang Ding, Minkyung Kwak, Guanglei Liu, Haixia Liu, Xiaonong Cheng, Yang Zhao, Xinqing Zhao
Summary: A novel multiphase Zr-30Ti-7Nb-4Sn alloy consisting of beta, alpha' and alpha '' phases was designed and fabricated to investigate the mechanical mechanisms responsible for the deformation behavior in multiphase Zr-based alloys involving two different martensites. The results reveal that extensive beta ->alpha '' stress-induced martensitic (SIM) transformation and the reorientation of pre-existing alpha '' martensitic variants occur during loading. Incomplete reverse alpha ''->beta SIM transformation takes place during unloading, leading to residual macroscopic strain in the specimen.
MATERIALS TODAY ADVANCES
(2022)
Article
Biotechnology & Applied Microbiology
Xin Wei, Miao Zhang, Guang-Yuan Wang, Guang-Lei Liu, Zhen-Ming Chi, Zhe Chi
Summary: In this study, engineered strains of A. pullulans var. aubasidani were found to be suitable for green fumaric acid production. The ornithine-urea cycle was identified as the key pathway for high level fumarate biosynthesis. Genetic modifications and overexpression led to the development of a strain that produced high yields of fumarate. This research is significant for global sustainable development and carbon neutrality.
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Xin Wei, Miao Zhang, Zhe Chi, Guang-Lei Liu, Zhen-Ming Chi
Summary: C-18:2 fatty acids play an important role in the cold and warm growth of psychrotrophic yeast, while C-18:3 fatty acids have no significant effect on cell growth. Additionally, the absence of C-18:2 fatty acids negatively affects cell wall development.
MARINE BIOTECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Bin Chen, Guanglei Liu, Minying Wu, Yudong Cao, Haibin Zhong, Jianfeng Shen, Mingxin Ye
Summary: Currently, there is a growing interest in the development of organohydrogel-based wearable flexible electronics (WFEs) due to their superior environmental stability compared to hydrogel-based WFEs. In this study, an efficient strategy is proposed to achieve the quick preparation of organohydrogels by utilizing the high reactivity of eutectic gallium-indium alloy and constructing a glycerol/water binary solvent system. The resulting organohydrogels, named liquid metal-based ion-conducting organohydrogels (LMIOs), demonstrate excellent environmental adaptability, high transparency, and remarkable mechanical properties and self-healing abilities, making them suitable for sensing human motions and applications in skin-attachable devices, robotics, and prosthetics.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Physical
Guang-lei Liu, Wen-chao Xue, Yu-hao Cao, Xiao-xuan Sun, Zhi-qiang Li, Fu-hai Xu, Hai-xia Liu, Jian-zhong Zhou
Summary: This study investigates the effects of laser shock processing (LSP) on the thermal fatigue life and crack growth behavior of the coating and bonding area of the brake disc. The results show that LSP can enhance the thermal fatigue performance of the brake disc repaired by laser cladding.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Materials Science, Multidisciplinary
Guanglei Liu, Wenchao Xue, Yuhao Cao, Zhiqiang Li, Xiaoxuan Sun, Fuhai Xu, Haixia Liu, Jianzhong Zhou
Summary: The effects of Laser Shock Peening (LSP) on the microhardness, residual stress, and microstructure of the Ni60 cladding layer and the combined area of the 20CrNiMo alloy were investigated. The results show that LSP can improve the microhardness, introduce residual compressive stress, and refine the microstructure. The residual compressive stress value is -538 MPa on the surface and -30 MPa at a depth of 2 mm.
JOURNAL OF LASER APPLICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Hao Chen, Cun-Cui Kong, Xin Wei, Zhe Chi, Guang-Lei Liu, Zhen-Ming Chi
Summary: In this study, an engineered strain of Aureobasidium melanogenum DFAK-ArgB6 overexpressing the ArgB gene was able to produce 3.0 g/L of L-piperazic acid from glucose during fed-batch fermentation. The yield was 55.6 mg L-piperazic acid/g glucose and the productivity was 24.8 mg/L/h, which is the highest reported so far. The partially purified L-piperazic acid had a purity of 86.4%.
PROCESS BIOCHEMISTRY
(2023)
