Antiproliferative Activity of Functionalized Histidine‐derived Au(I) bis ‐NHC Complexes for Bioconjugation

Insight into the Substitution Mechanism of Antitumor Au(I) N-Heterocyclic Carbene Complexes by Cysteine and Selenocysteine

(2020) Iogann Tolbatov et al.   INORGANIC CHEMISTRY

Coinage metal complexes of N‐heterocyclic carbene bearing nitrile functionalization: Synthesis and photophysical properties

(2019) Sunusi Y. Hussaini et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Anticancer metal-N-heterocyclic carbene complexes of gold, platinum and palladium

(2018) Taotao Zou et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Synthesis, characterization and derivatization of hydroxyl-functionalized iron(ii) bis(NHC) complexes

(2018) Anja C. Lindhorst et al.   DALTON TRANSACTIONS

Zwitterionic Rhodium and Iridium Complexes Based on a Carboxylate Bridge-Functionalized Bis-N-heterocyclic Carbene Ligand: Synthesis, Structure, Dynamic Behavior, and Reactivity

(2018) Raquel Puerta-Oteo et al.   INORGANIC CHEMISTRY

Medicinal Applications of Gold(I/III)-Based Complexes Bearing N -Heterocyclic Carbene and Phosphine Ligands

(2018) Bruno Dominelli et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin

(2018) Jiaying Han et al.   BIOCONJUGATE CHEMISTRY

Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric Approaches

(2017) Özden Karaca et al.   INORGANIC CHEMISTRY

The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review)

(2017) Fatima Ardito et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

New Cu(II) complexes with pyrazolyl derived Schiff base ligands: Synthesis and biological evaluation

(2017) Nádia Ribeiro et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Intracellular distribution and stability of a luminescent rhenium(i) tricarbonyl tetrazolato complex using epifluorescence microscopy in conjunction with X-ray fluorescence imaging

(2017) J. L. Wedding et al.   Metallomics

Biscarbene gold(i) complexes: structure–activity-relationships regarding antibacterial effects, cytotoxicity, TrxR inhibition and cellular bioavailability

(2017) Claudia Schmidt et al.   MedChemComm

N-Heterocyclic Carbene-Gold(I) Complexes Conjugated to a Leukemia-Specific DNA Aptamer for Targeted Drug Delivery

(2016) Weijia Niu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organometallic–Peptide Bioconjugates: Synthetic Strategies and Medicinal Applications

(2016) Bauke Albada et al.   CHEMICAL REVIEWS

Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

(2016) Wukun Liu et al.   COORDINATION CHEMISTRY REVIEWS

Effects of histidin-2-ylidene vs. imidazol-2-ylidene ligands on the anticancer and antivascular activity of complexes of ruthenium, iridium, platinum, and gold

(2016) Florian Schmitt et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The state-of-play and future of platin drugs

(2015) M. Apps et al.   ENDOCRINE-RELATED CANCER

Allylpalladium(II) Histidylidene Complexes and Their Application inZ-Selective Transfer Semihydrogenation of Alkynes

(2015) Ruben M. Drost et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Structure–activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme

(2015) Julie Charton et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A bioorganometallic chemistry perspective: Organometallic chemistry at the interface with biology

(2015) Richard H. Fish   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Post-functionalization of metal–NHC complexes: A useful toolbox for bioorganometallic chemistry (and beyond)?

(2015) Federico Cisnetti et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Spectroscopic and Structural Properties of Bridge-Functionalized Dinuclear Coinage-Metal (Cu, Ag, and Au) NHC Complexes: A Comparative Study

(2015) Rui Zhong et al.   ORGANOMETALLICS

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo

(2014) Taotao Zou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Benzyl-substituted metallocarbene antibiotics and anticancer drugs

(2014) F. Hackenberg et al.   DALTON TRANSACTIONS

Synthesis, Characterization, and Cytotoxic Activity of AuIN,S-Heterocyclic Carbenes Derived from Peptides ContainingL-Thiazolylalanine

(2014) Alejandro Gutiérrez et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Recent developments of metal N-heterocyclic carbenes as anticancer agents

(2014) Sainath Babaji Aher et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cellular Transport Mechanisms of Cytotoxic Metallodrugs: An Overview beyond Cisplatin

(2014) Sarah Spreckelmeyer et al.   MOLECULES

Water-Soluble Mono- and Dimethyl N-Heterocyclic Carbene Platinum(II) Complexes: Synthesis and Reactivity

(2014) Edwin A. Baquero et al.   ORGANOMETALLICS

Synthesis, Characterization, and Catalytic Activity of Alcohol-Functionalized NHC Gold(I/III) Complexes

(2014) Béatrice Jacques et al.   ORGANOMETALLICS

Peptide-tethered monodentate and chelating histidylidene metal complexes: synthesis and application in catalytic hydrosilylation

(2013) Angèle Monney et al.   DALTON TRANSACTIONS

Dinuclear gold(I) and gold(III) complexes involving di(N-heterocyclic carbene) ligands – Synthesis, characterization and DFT studies

(2013) Catherine Hemmert et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Cellular Uptake Mechanisms of an Antitumor Ruthenium Compound: The Endosomal/Lysosomal System as a Target for Anticancer Metal-Based Drugs

(2013) Leonor Côrte-Real et al.   MICROSCOPY AND MICROANALYSIS

Orthogonally Protected Artificial Amino Acid as Tripod Ligand for Automated Peptide Synthesis and Labeling with [99mTc(OH2)3(CO)3]+

(2012) Yunjun Shen et al.   BIOCONJUGATE CHEMISTRY

A chelating tetrapeptide rhodium complex comprised of a histidylidene residue: biochemical tailoring of an NHC-Rh hydrosilylation catalyst

(2012) Angèle Monney et al.   CHEMICAL COMMUNICATIONS

Stereospecific synthesis and catalytic activity of l-histidylidene metal complexes

(2012) Angèle Monney et al.   DALTON TRANSACTIONS

Synthesis and Biological Activity of Ester- and Amide-Functionalized Imidazolium Salts and Related Water-Soluble Coinage Metal N-Heterocyclic Carbene Complexes

(2012) Maura Pellei et al.   INORGANIC CHEMISTRY

Dimeric Gold Bis(carbene) Complexes by Transmetalation in Water

(2012) Jérémy Cure et al.   ORGANOMETALLICS

Synthesis and catalytic activity of histidine-based NHC ruthenium complexes

(2011) Angèle Monney et al.   DALTON TRANSACTIONS

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

(2011) Ana-Maria Florea et al.   Cancers

Conformational Control of Integrin-Subtype Selectivity in isoDGR Peptide Motifs: A Biological Switch

(2010) Andreas O. Frank et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Coinage Metal−N-Heterocyclic Carbene Complexes

(2009) Joseph C. Y. Lin et al.   CHEMICAL REVIEWS

On the medicinal chemistry of gold complexes as anticancer drugs

(2009) Ingo Ott   COORDINATION CHEMISTRY REVIEWS

Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

(2009) Alberto Bindoli et al.   COORDINATION CHEMISTRY REVIEWS

The Role of Thiols and Disulfides on Protein Stability

(2009) Maulik Trivedi et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Synthesis, structural characterisation and anti-proliferative activity of NHC gold amino acid and peptide conjugates

(2009) Jessica Lemke et al.   DALTON TRANSACTIONS

A bifunctional platinum(II) antitumor agent that forms DNA adducts with affinity for the estrogen receptor

(2008) Eunsuk Kim et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mitochondria-Targeted Chemotherapeutics: The Rational Design of Gold(I)N-Heterocyclic Carbene Complexes That Are Selectively Toxic to Cancer Cells and Target Protein Selenols in Preference to Thiols

(2008) James L. Hickey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glutathione: Overview of its protective roles, measurement, and biosynthesis

(2008) Henry Jay Forman et al.   MOLECULAR ASPECTS OF MEDICINE