Signaling mechanisms of μ-opioid receptor (MOR) in the hippocampus: disinhibition versus astrocytic glutamate regulation

Five Decades of Research on Opioid Peptides: Current Knowledge and Unanswered Questions

(2020) Lloyd D. Fricker et al.   MOLECULAR PHARMACOLOGY

Microglia Express Mu Opioid Receptor: Insights From Transcriptomics and Fluorescent Reporter Mice

(2019) Tando Maduna et al.   Frontiers in Psychiatry

Acute Stress Facilitates LTD Induction at Glutamatergic Synapses in the Hippocampal CA1 Region by Activating μ-Opioid Receptors on GABAergic Neurons

(2019) Ka-Min Fan et al.   Frontiers in Neuroscience

Dentate gyrus μ-opioid receptor-mediated neurogenic processes are associated with alterations in morphine self-administration

(2019) Haolin Zhang et al.   Scientific Reports

Hippocampal µ-opioid receptors on GABAergic neurons mediate stress-induced impairment of memory retrieval

(2019) Mei-Mei Shi et al.   MOLECULAR PSYCHIATRY

Activation of Astrocytic μ-Opioid Receptor Causes Conditioned Place Preference

(2019) Min-Ho Nam et al.   Cell Reports

Opioid-Mediated Astrocyte–Neuron Signaling in the Nucleus Accumbens

(2019) Michelle Corkrum et al.   Cells

A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice

(2018) Fangmiao Sun et al.   CELL

Stress Impacts the Regulation Neuropeptides in the Rat Hippocampus and Prefrontal Cortex

(2018) Wenxue Li et al.   PROTEOMICS

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

(2018) Tommaso Patriarchi et al.   SCIENCE

Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes

(2018) Min-Ho Nam et al.   Experimental Neurobiology

Development of a Region-Specific Physiologically Based Pharmacokinetic Brain Model to Assess Hippocampus and Frontal Cortex Pharmacokinetics

(2018) Zaril Zakaria et al.   Pharmaceutics

Activation of Astrocytic μ-opioid Receptor Elicits Fast Glutamate Release Through TREK-1-Containing K2P Channel in Hippocampal Astrocytes

(2018) Dong Ho Woo et al.   Frontiers in Cellular Neuroscience

Historical Review

(2018) Shaocheng Wang   CELL TRANSPLANTATION

Astrocytes’ Contribution to Adult Neurogenesis in Physiology and Alzheimer’s Disease

(2018) Frédéric Cassé et al.   Frontiers in Cellular Neuroscience

Epidemiology of Opioid Abuse and Addiction

(2017) Jonathan Green   Journal of Emergency Nursing

The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential

(2017) Johannes Burtscher et al.   Frontiers in Molecular Neuroscience

Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by β-arrestin2 and c-Src

(2017) Fiona A. Bull et al.   Scientific Reports

Morphine Modulates Adult Neurogenesis and Contextual Memory by Impeding the Maturation of Neural Progenitors

(2016) Yue Zhang et al.   PLoS One

Opioid Receptor-Dependent Sex Differences in Synaptic Plasticity in the Hippocampal Mossy Fiber Pathway of the Adult Rat

(2015) L. C. Harte-Hargrove et al.   JOURNAL OF NEUROSCIENCE

Structural insights into µ-opioid receptor activation

(2015) Weijiao Huang et al.   NATURE

Understanding opioid reward

(2015) Howard L. Fields et al.   TRENDS IN NEUROSCIENCES

Effect of acute fentanyl treatment on synaptic plasticity in the hippocampal CA1 region in rats

(2015) Hai Tian et al.   Frontiers in Pharmacology

Pharmacodynamic effects of oral oxymorphone: abuse liability, analgesic profile and direct physiologic effects in humans

(2014) Shanna Babalonis et al.   ADDICTION BIOLOGY

Loss of the mu opioid receptor induces strain-specific alterations in hippocampal neurogenesis and spatial learning

(2014) T.P. Cominski et al.   NEUROSCIENCE

Regulation and Function of Adult Neurogenesis: From Genes to Cognition

(2014) James B. Aimone et al.   PHYSIOLOGICAL REVIEWS

The effects of astrocytes on differentiation of neural stem cells are influenced by knock-down of the glutamate transporter, GLT-1

(2013) Yijing Guo et al.   NEUROCHEMISTRY INTERNATIONAL

Stress differentially alters mu opioid receptor density and trafficking in parvalbumin-containing interneurons in the female and male rat hippocampus

(2013) Teresa A. Milner et al.   SYNAPSE

TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation

(2012) Dong Ho Woo et al.   CELL

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

(2012) Aashish Manglik et al.   NATURE

Multiple Targets of  -Opioid Receptor-Mediated Presynaptic Inhibition at Primary Afferent A - and C-Fibers

(2011) B. Heinke et al.   JOURNAL OF NEUROSCIENCE

The Influences of Reproductive Status and Acute Stress on the Levels of Phosphorylated Mu Opioid Receptor Immunoreactivity in Rat Hippocampus

(2011) Keith L. Gonzales et al.   Frontiers in Endocrinology

Mu opioid receptor mRNA expression, binding, and functional coupling to G-proteins in human epileptic hippocampus

(2010) Manola Cuellar-Herrera et al.   HIPPOCAMPUS

Drug Addiction and the Memory Systems of the Brain

(2009) T.W. Robbins et al.   Annals of the New York Academy of Sciences

Ovarian steroids alter mu opioid receptor trafficking in hippocampal parvalbumin GABAergic interneurons

(2009) Annelyn Torres-Reveron et al.   EXPERIMENTAL NEUROLOGY

Effect of chronic morphine on the dentate gyrus neurogenic microenvironment

(2009) A.A. Arguello et al.   NEUROSCIENCE

Ovarian steroids modulate leu-enkephalin levels and target leu-enkephalinergic profiles in the female hippocampal mossy fiber pathway

(2008) Annelyn Torres-Reveron et al.   BRAIN RESEARCH

Time course of morphine's effects on adult hippocampal subgranular zone reveals preferential inhibition of cells in S phase of the cell cycle and a subpopulation of immature neurons

(2008) A.A. Arguello et al.   NEUROSCIENCE

Layer selective presynaptic modulation of excitatory inputs to hippocampal cornu Ammon 1 by μ-opioid receptor activation

(2007) A.R. McQuiston   NEUROSCIENCE

75 years of opioid research: the exciting but vain quest for the Holy Grail

(2006) Alistair D Corbett et al.   BRITISH JOURNAL OF PHARMACOLOGY