Article
Polymer Science
Chih-Jen Chang, Manikandan Venkatesan, Chia-Jung Cho, Ping-Yu Chung, Jayashree Chandrasekar, Chen-Hung Lee, Hsin-Ta Wang, Chang-Ming Wong, Chi-Ching Kuo
Summary: Starch-based biodegradable foams were synthesized using industrial starch and supercritical CO2. The foam properties were improved by modifying the surface of thermoplastic starch and optimizing the foam-forming process. The resulting composite foam with PBAT exhibited good flexibility and low foam density.
Article
Polymer Science
Zehao Li, Hui Li, Muxi Wang, Zhongyan Zhang, Liting Yang, Lijun Ma, Hong Liu
Summary: By adding nano-silica, the tensile strength of poly(butylene adipate-co-terephthalate)/thermoplastic hydroxypropyl starch (PBAT/TPHSg-SiO2) composite films is significantly improved, with a 35% increase in horizontal tensile strength and a 21% increase in vertical tensile strength after adding 4 phr of nano-silica. When the content of TPHSg-4SiO2 is 40%, the composite films have horizontal and vertical tensile strengths of 9.82 and 12.09 MPa, respectively, and the elongation at break exceeds 500%. Electron micrographs show that TPHSg-4SiO2 is well dispersed in PBAT and exhibits a bi-continuous phase structure at a TPHSg-4SiO2 content of 40%. The blowing PBAT/TPHSg-4SiO2 composite films effectively reduce the cost and still show better mechanical properties, suitable for packaging applications.
Article
Biochemistry & Molecular Biology
Hao-Hui Wang, Si-Jie Zhou, Shao-Jun Xiong, Qin Liu, Huafeng Tian, Shixin Yu, Tong-Qi Yuan
Summary: Utilizing starch as a renewable filler blended with PBAT can create cost-effective and high-performance biodegradable materials. The thermal processing properties of starch can be manipulated by its plasticized behavior. In this study, epoxidized soybean oil and glycerol were used as plasticizers for starch and integrated with PBAT, resulting in a starch-based biodegradable blend film with balanced properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Chih-Jen Chang, Jayashree Chandrasekar, Chia-Jung Cho, Manikandan Venkatesan, Pin-Shu Huang, Ching-Wei Yang, Hsin-Ta Wang, Chang-Ming Wong, Chi-Ching Kuo
Summary: In this study, the effects of polyethylene glycol (PEG) with or without silane A (SA) on the foam properties of thermoplastic starch (TPS)/poly(butylene adipate-co-terephthalate) (PBAT) blends were investigated. It was found that PEG acted as a plasticizer while SA acted as a compatibilizer. The addition of SA and PEG resulted in foams with lower density and better cell structure compared to foams without SA.
Article
Biochemistry & Molecular Biology
Thanatcha Tuntiworadet, Rangrong Yoksan
Summary: Recently, there has been an increasing global awareness of the negative environmental impacts of single-use plastics due to their nonbiodegradability and tendency to end up in the ocean. Thermoplastic starch (TPS) is a viable alternative material for single-use products due to its high biodegradability, low cost, and nontoxicity. However, TPS has moisture sensitivity and poor mechanical properties and processability. Blending TPS with biodegradable polyesters, such as PBAT, can enhance its practical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Polymer Science
C. Aversa, M. Barletta, G. Cappiello, A. Gisario
Summary: PBAT is a compostable biopolyester with great commercial interest. It is expected to become the leading flexible bioplastic in the next few years, surpassing other contenders due to its lower price, ease in processability, and high ductility. PBAT is often blended with PLA, a rigid bio-based polymer, to create high performance and multi-functional biodegradable plastics. This work aims to provide a comprehensive overview of PBAT blends, specifically focusing on PBAT/PLA blends and strategies for compatibilization.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Polymer Science
Raja Venkatesan, Krishnapandi Alagumalai, Seong-Cheol Kim
Summary: The study finds that the biodegradable polymer PBAT can be improved by blending with kaolin clay to form composites. The structure and morphology of the composites were evaluated using FTIR, XRD, SEM, and TEM. TGA analysis shows that the PBAT composite with 5.0 wt% kaolin clay exhibits the best characteristics. Compared to pure PBAT, the PBAT/kaolin composites have higher tensile strength and lower oxygen and water vapor transmission rates. The antimicrobial property of the composites inhibits the growth of bacteria, making them potential packaging materials for extending the shelf life of food.
Article
Materials Science, Multidisciplinary
Sung Kyu Kim, Hyun Wook Jung, Dasom Son, Jae Hyeok Han, DongHo Kang, Sang In Kang, Junhyuk Lee, Jin Kie Shim
Summary: In this study, a thermoplastic starch/poly(butylene adipate-co-terephthalate) (TPS/PBAT) blend with improved compatibility, mechanical properties, and water resistance was successfully prepared using in situ reactive compatibilization. The addition of 3% copolymer showed the best results, increasing the tensile strength of the blend and reducing the size of TPS domains in the PBAT matrix. The complex viscosity, storage modulus, and loss modulus also increased with increasing copolymer content, indicating enhanced compatibility between TPS and PBAT. Furthermore, the water resistance improved, as evidenced by increased contact angle and water vapor barrier properties.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Applied
Meiyan Zhao, Zhikun Zhang, Hong Cai, Li Wang, Changying Hu, Dan Li, Yu Chen, Yongfeng Kang, Li Li
Summary: In this study, a thermoplastic starch/polylactic acid/poly (butylene adipate-co-terephthalate) (TPS/PLA/PBAT) film was successfully produced, and the humidity of the microenvironment in the package was effectively controlled by adjusting the moisture permeability of the film, prolonging the shelf life of straw mushrooms.
Article
Biochemistry & Molecular Biology
Xiaosong Zhai, Rui Zhang, Wentao Wang, Hanxue Hou
Summary: Biodegradable films with different weight proportions of thermoplastic starch (TPS) and poly(butylene adipate-co-terephthalate) (PBAT) were prepared. The relationship between the phase morphologies and mechanical properties of TPS/PBAT composite films was investigated. The results showed that the mechanical properties were correlated with the continuity indices of the two phases, with a positive correlation with the continuity index of PBAT and a negative correlation with that of TPS.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Zhaoyang Niu, Fangping Chen, He Zhang, Changsheng Liu
Summary: In this study, ternary blends of high content TPS, PBAT, and PBS were melt-compounded. The dispersion of PBS and PBAT minor phases improved tensile strength and elongation at break. TPS/PBS/PBAT60/10/30 blend showed good balance in strength and toughness. The morphological analysis revealed a core-shell structure. With increasing PBAT composition, changes in phase morphology and decreased values of complex viscosity and storage modulus were observed. The thermal resistance and melt flow properties were also studied.
Article
Materials Science, Composites
Mariam Keskes, Melinda Desse, Christian Carrot, Mohamed Jaziri
Summary: This paper investigates the interactions between thermoplastic starch (TPS) and cellulose in Poly(butylene adipate-co-terephthalate) (PBAT), melt-blended composites. The results indicate that the interaction between TPS and cellulose is the cause of the adhesion between the components and the formation of biphasic agglomerates.
JOURNAL OF THERMOPLASTIC COMPOSITE MATERIALS
(2023)
Article
Engineering, Chemical
Xuegang Jiang, Jinheng Wang, Jianting Zhang, Jikui Wang, Weihong Guo
Summary: In this paper, PBAT/thermoplastic starch (TPS) complexes were prepared using epoxidized soybean oil (ESO) as a reactive compatibilizer. Results showed that ESO could form a chemical bonding interface with PBAT and TPS. The tensile strength, elongation at break, tear strength and optical transparency of the PBAT/TPS/5%ESO composites were significantly improved compared to PBAT/TPS.
POLYMER ENGINEERING AND SCIENCE
(2023)
Article
Polymer Science
Nanthicha Thajai, Pornchai Rachtanapun, Sarinthip Thanakkasaranee, Winita Punyodom, Patnarin Worajittiphon, Yuthana Phimolsiripol, Noppol Leksawasdi, Sukunya Ross, Pensak Jantrawut, Kittisak Jantanasakulwong
Summary: In this study, biodegradable starch-based polymers were developed by melt-blending modified thermoplastic starch with poly(butylene succinate) blended with epoxy resin. The results showed that the mechanical properties, water resistance, morphology, and thermal stability of the starch-based polymers were improved by adding poly(butylene succinate) and epoxy resin.
Article
Materials Science, Multidisciplinary
Seo-Hwa Hong, Seok-Ho Hwang
Summary: In this study, high-content lignin-reinforced poly(butylene adipate-co-terephthalate) (PBAT) biocomposites were successfully constructed, and the thermal, mechanical, and foaming properties were investigated. The results showed that the addition of lignin increased the crystallization temperature and affected the foam structure. Therefore, this high-content lignin-reinforced material can be used as a sustainable foam packaging material.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Applied
Nadege Follain, Jiawei Ren, Eric Pollet, Luc Averous
Summary: The barrier performances of different starch-based nano-biocomposites in terms of water vapor sorption properties, gas and water barrier performances were analyzed. The results showed that halloysite nanoclay has the potential to enhance the properties of plasticized starch matrix. Glycerol-plasticized starch films exhibited better interfacial interactions and more stable hydrogen bonds.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Multidisciplinary
A. Duval, D. Vidal, A. Sarbu, W. Rene, L. Averous
Summary: A new method for synthesizing lignin-based liquid polyols has been developed, enabling the production of aromatic polyols in a single step with tunable properties, suitable for the preparation of polyurethane foams.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Polymer Science
Alejandro Torres-Rodriguez, Luc Averous, Eric Pollet, Gerardo de Jesus Sosa-Santillan, Alejandro Zugasti-Cruz, Crystel Aleyvick Sierra-Rivera, Nancy Veronica Perez-Aguilar, Marco Antonio Garcia-Lobato, Ernesto Oyervides-Munoz
Summary: Three novel polyaspartate derivatives with antibacterial properties and low hemolytic effects were synthesized and tested, showing potential as antimicrobial agents.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Review
Chemistry, Multidisciplinary
Agathe Mouren, Luc Averous
Summary: Polyurethanes are a versatile polymer family that can be synthesized using sustainable feedstocks to achieve specific properties. Different sustainable building blocks can be used to develop polyurethanes with various characteristics such as rigidity, flexibility, and transparency. This review provides an overview of the synthesis of sustainable polyurethanes using renewable products and discusses their applications in fields such as building, transportation, packaging, and biomedicine.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Matteo Andrea Lucherelli, Antoine Duval, Luc Averous
Summary: This study reports the synthesis of novel dually crosslinked covalent adaptable networks (CAN) using a single biobased building block, 2,5-furandicarboxaldehyde (FDC), to obtain dynamic associative imine linkages and dissociative Diels-Alder adducts. The linear polyimine based on FDC showed fast coupling with maleimides in Diels-Alder reactions, leading to the rapid formation of polymer networks. The resulting sustainable polymer systems exhibited behavior intermediate to vitrimers and dissociative CANs, with tunable mechanical behavior and excellent reprocessability.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Correction
Polymer Science
Antoine Duval, Alexandru Sarbu, Florent Dalmas, David Albertini, Luc Averous
Article
Chemistry, Multidisciplinary
L. Polo Fonseca, A. Duval, E. Luna, M. Ximenis, S. De Meester, L. Averous, H. Sardon
Summary: Polyurethanes (PUs) are widely used polymers with various applications, but they generate long-lasting and potentially polluting waste. This review focuses on the latest advances in chemical and biological recycling routes for PUs, which can potentially recover and reuse monomers for new PUs with identical properties. The importance of using life cycle assessment (LCA) to find sustainable solutions and promote industrial implementation of recycling approaches is also highlighted.
CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY
(2023)
Article
Green & Sustainable Science & Technology
Lisa Sougrati, Sophie Wendels, Sorina Dinescu, Liliana-Roxana Balahura (Stamat), Lea Sleiman, Luc Averous
Summary: In this study, sustainable macromolecular architectures were designed and tested to synthesize fully biobased polyfunctional NCO terminated prepolymers. Two-component adhesive systems were prepared, and the properties of the resulting biobased polyurethanes were studied, showing good biocompatibility and potential biomedical application.
SUSTAINABLE MATERIALS AND TECHNOLOGIES
(2023)
Article
Agricultural Engineering
Federico Cerrone, Binbin Zhou, Agathe Mouren, Luc Averous, Stephen Conroy, Jeremy C. Simpson, Kevin E. O'Connor, Tanja Narancic
Summary: Polyhydroxyalkanoates (PHAs) are considered as a potential replacement for petrochemical plastics. This study demonstrates that a metabolically versatile Pseudomonas umsongensis can synthesize a blend of short chain length (scl) and medium chain length (mcl)-PHA. The resulting blend exhibits specific physical and mechanical properties.
BIORESOURCE TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Lisa Sougrati, Antoine Duval, Luc Averous
Summary: In the past two decades, covalent adaptable networks (CANs) have emerged as an important class of polymer materials that combine the benefits of thermoplastics and thermosets. These materials can undergo repeated processing cycles by incorporating dynamic covalent bonds within a cross-linked network. By integrating renewable resources, such as lignins, into these innovative systems, sustainable materials can be developed in line with the circular bioeconomy. By modifying lignin into liquid polyols and polyacetoacetates, an innovative strategy was developed to create recyclable lignin-based vinylogous urethane (VU) networks with tunable structures and properties. These biobased aromatic vitrimers exhibited fast stress-relaxations, allowing for easy and fast mechanical reprocessing, and demonstrated healing ability, enhancing their lifecycle and sustainability.
Article
Polymer Science
Alexis Morinval, Luc Averous
Summary: This study developed a thermally responsive network based on reversible Diels-Alder reaction, by chemically modifying AMS and PBAT. It successfully addressed the incompatibility between the two materials, offering potential for developing high-performance materials in the circular bioeconomy.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Polymer Science
Agathe Mouren, Luc Averous
Summary: This study focuses on the synthesis and structure-property relationships of sustainable aromatic TPUs derived from different potential sustainable resources. The presence of aromatic rings enhances phase segregation and improves thermo-mechanical and mechanical properties. Conversely, methoxy groups and the asymmetry of the aromatic diisocyanate hinder the organization of the hard segments, leading to reduced structuration and lower mechanical properties of TPUs.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Agriculture, Multidisciplinary
Rangrong Yoksan, Pawika Towongphaichayonte
Summary: The study demonstrates the successful encapsulation of vitexin into mPEG-g-CTS/ALG nanoparticles, which are suitable for oral intestinal-specific delivery systems.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Polymer Science
Antoine Duval, Luc Averous
Summary: An original segmented thermoplastic polyurethane (TPU) was synthesized with a biobased aromatic chain extender prepared from caffeic acid (EC-diol). The TPU exhibited phase segregation between soft and hard segments, leading to remarkable mechanical and thermal properties. The unique structure of EC-diol allowed for crosslinking through photodimerization under UV irradiation.
Article
Materials Science, Multidisciplinary
Aleksandra Buzarovska, Aida Selaru, Mirela Serban, Gratiela G. Pircalabioru, Marieta Costache, Mariacristina Cocca, Gennaro Gentile, Luc Averous, Sorina Dinescu
Summary: Renewable foams based on blends of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were fabricated and evaluated for their biocompatibility and antibacterial properties for wound dressing applications.
JOURNAL OF MATERIALS SCIENCE
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
