Cancer‐associated adipocytes promote pancreatic cancer progression through SAA1 expression

Prognostic and predictive factors in pancreatic cancer

(2020) Emanuela Dell’Aquila et al.   Oncotarget

Cancer associated fibroblasts sculpt tumour microenvironment by recruiting monocytes and inducing immunosuppressive PD-1+ TAMs

(2019) Betul Gok Yavuz et al.   Scientific Reports

The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice

(2019) Ana S. Leal et al.   Scientific Reports

Cancer-associated adipocytes: key players in breast cancer progression

(2019) Qi Wu et al.   Journal of Hematology & Oncology

Adiposity and gastrointestinal cancers: epidemiology, mechanisms and future directions

(2018) Neil Murphy et al.   Nature Reviews Gastroenterology & Hepatology

Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors

(2018) Magdolna Djurec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advanced pancreatic cancer: a meta-analysis of clinical trials over thirty years

(2018) Bradley R. Hall et al.   Oncotarget

Metabolic Patterning on a Chip: Towards in vitro Liver Zonation of Primary Rat and Human Hepatocytes

(2018) Young Bok Kang et al.   Scientific Reports

Pancreatic Cancer and Obesity: Molecular Mechanisms of Cell Transformation and Chemoresistance

(2018) Priscilla Cascetta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The tumor-stromal ratio as a strong prognosticator for advanced gastric cancer patients: proposal of a new TSNM staging system

(2017) Chunwei Peng et al.   JOURNAL OF GASTROENTEROLOGY

Unique cellular interactions between pancreatic cancer cells and the omentum

(2017) Valerya Feygenzon et al.   PLoS One

Molecular imaging of aberrant crypt foci in the human colon targeting glutathione S-transferase P1-1

(2017) Naoki Muguruma et al.   Scientific Reports

Key players in pancreatic cancer-stroma interaction: Cancer-associated fibroblasts, endothelial and inflammatory cells

(2016) Michael Friberg Bruun Nielsen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1

(2016) Chi Lam Au Yeung et al.   Nature Communications

MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma

(2016) Tetsu Tomonari et al.   Oncotarget

Targeting tumor-associated macrophages to combat pancreatic cancer

(2016) Ran Cui et al.   Oncotarget

Serum amyloid A expression in the breast cancer tissue is associated with poor prognosis

(2016) Mu Yang et al.   Oncotarget

Adipocytes WNT5a mediated dedifferentiation: a possible target in pancreatic cancer microenvironment

(2016) Elena Zoico et al.   Oncotarget

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells

(2016) Sören V. Siegmund et al.   PLoS One

Stromal biology and therapy in pancreatic cancer: a changing paradigm

(2015) Albrecht Neesse et al.   GUT

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Pancreatic cancer: The microenvironment needs attention too!

(2015) M.V. Apte et al.   PANCREATOLOGY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High-Fat, High-Calorie Diet Promotes Early Pancreatic Neoplasia in the Conditional KrasG12D Mouse Model

(2013) D. W. Dawson et al.   Cancer Prevention Research

Adipocyte-Derived Fibroblasts Promote Tumor Progression and Contribute to the Desmoplastic Reaction in Breast Cancer

(2013) L. Bochet et al.   CANCER RESEARCH

A High-Fat Diet Activates Oncogenic Kras and COX2 to Induce Development of Pancreatic Ductal Adenocarcinoma in Mice

(2013) Bincy Philip et al.   GASTROENTEROLOGY

Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness

(2012) Enza Lonardo et al.   CELL CYCLE

Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice

(2012) Paul J Grippo et al.   GUT

Body mass index, abdominal fatness and pancreatic cancer risk: a systematic review and non-linear dose–response meta-analysis of prospective studies

(2011) D. Aune et al.   ANNALS OF ONCOLOGY

Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion

(2011) B. Dirat et al.   CANCER RESEARCH

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

Targeting stroma to treat cancers

(2011) Boris Engels et al.   SEMINARS IN CANCER BIOLOGY

CD10+ Pancreatic Stellate Cells Enhance the Progression of Pancreatic Cancer

(2010) Naoki Ikenaga et al.   GASTROENTEROLOGY

Peripancreatic Fat Invasion Is an Independent Predictor of Poor Outcome Following Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma

(2010) Nigel Balfour Jamieson et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Paracrine Hedgehog Signaling in Cancer

(2009) J.-W. Theunissen et al.   CANCER RESEARCH

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

(2008) R. F. Hwang et al.   CANCER RESEARCH

The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma

(2008) Mert Erkan et al.   Clinical Gastroenterology and Hepatology