Oxiapoptophagy: A type of cell death induced by some oxysterols

Prevention of 7-Ketocholesterol-Induced Overproduction of Reactive Oxygen Species, Mitochondrial Dysfunction and Cell Death with Major Nutrients (Polyphenols, ω3 and ω9 Unsaturated Fatty Acids) of the Mediterranean Diet on N2a Neuronal Cells

(2020) Aline Yammine et al.   MOLECULES

Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes

(2019) Randa Sghaier et al.   FREE RADICAL RESEARCH

Profile of Fatty Acids, Tocopherols, Phytosterols and Polyphenols in Mediterranean Oils (Argan Oils, Olive Oils, Milk Thistle Seed Oils and Nigella Seed Oil) and Evaluation of their Antioxidant and Cytoprotective Activities

(2019) Amira Zarrouk et al.   CURRENT PHARMACEUTICAL DESIGN

Prophylaxis of non-communicable diseases: Why fruits and vegetables may be better chemopreventive agents than dietary supplements based on isolated phytochemicals?

(2019) Izabela Koss-Mikołajczyk et al.   CURRENT PHARMACEUTICAL DESIGN

7-Ketocholesterol and 7β-hydroxycholesterol: In vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity

(2019) Anne Vejux et al.   BIOCHEMICAL PHARMACOLOGY

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters

(2019) Stephen P H Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

(2019) Stephen P H Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol

(2019) Randa Sghaier et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Aging, lifestyle and dementia

(2019) Devin Wahl et al.   NEUROBIOLOGY OF DISEASE

7-Ketocholesterol in disease and aging

(2019) Amelia Anderson et al.   Redox Biology

Implication of oxysterols in chronic inflammatory human diseases

(2018) Gabriella Testa et al.   BIOCHIMIE

Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol

(2018) Thomas Nury et al.   BIOCHIMIE

Prevention of 7-ketocholesterol-induced side effects by natural compounds

(2018) F Brahmi et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Lipid Oxidation Products in the Pathogenesis of Inflammation-related Gut Diseases

(2018) Barbara Sottero et al.   CURRENT MEDICINAL CHEMISTRY

Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases

(2018) Charleen T. Chu   NEUROBIOLOGY OF DISEASE

Mitochondrial Permeability Transition: A Molecular Lesion with Multiple Drug Targets

(2018) Thomas Briston et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Regulation of selective autophagy: the p62/SQSTM1 paradigm

(2017) Trond Lamark et al.   Essays in Biochemistry

Cholesterol and related sterols autoxidation

(2017) Chiara Zerbinati et al.   FREE RADICAL BIOLOGY AND MEDICINE

Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N

(2017) Asmaa Badreddine et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD

(2017) Thomas Nury et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Attenuation of 7-ketocholesterol-induced overproduction of reactive oxygen species, apoptosis, and autophagy by dimethyl fumarate on 158 N murine oligodendrocytes

(2017) Amira Zarrouk et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, cholesterol and cholesterol precursors

(2017) Valerio Leoni et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

(2017) Simon D Harding et al.   NUCLEIC ACIDS RESEARCH

Oxidative Stress-Mediated Atherosclerosis: Mechanisms and Therapies

(2017) Xinyu Yang et al.   Frontiers in Physiology

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Autophagy

(2016) Yun Luo et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Oxysterols: From cholesterol metabolites to key mediators

(2016) Valentin Mutemberezi et al.   PROGRESS IN LIPID RESEARCH

ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms

(2015) Lulu Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3)

(2015) Thomas Nury et al.   STEROIDS

An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system

(2015) Asmaa Badreddine et al.   STEROIDS

Involvement of oxysterols in age-related diseases and ageing processes

(2014) Amira Zarrouk et al.   AGEING RESEARCH REVIEWS

On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO

(2014) Ingemar Björkhem et al.   JOURNAL OF LIPID RESEARCH

Induction of oxiapoptophagy, a mixed mode of cell death associated with oxidative stress, apoptosis and autophagy, on 7-ketocholesterol-treated 158N murine oligodendrocytes: Impairment by α-tocopherol

(2013) Thomas Nury et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Absence of correlation between oxysterol accumulation in lipid raft microdomains, calcium increase, and apoptosis induction on 158N murine oligodendrocytes

(2013) Kévin Ragot et al.   BIOCHEMICAL PHARMACOLOGY

Markers of oxidant stress that are clinically relevant in aging and age-related disease

(2013) Kimberly D. Jacob et al.   MECHANISMS OF AGEING AND DEVELOPMENT

OSBP-Related Proteins: Liganding by Glycerophospholipids Opens New Insight into Their Function

(2013) Vesa Olkkonen   MOLECULES

Five decades with oxysterols

(2012) Ingemar Björkhem   BIOCHIMIE

Improved Mitochondrial Function with Diet-Induced Increase in Either Docosahexaenoic Acid or Arachidonic Acid in Membrane Phospholipids

(2012) Ramzi J. Khairallah et al.   PLoS One

Conversion of 7-Dehydrocholesterol to 7-Ketocholesterol Is Catalyzed by Human Cytochrome P450 7A1 and Occurs by Direct Oxidation without an Epoxide Intermediate

(2011) Raku Shinkyo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caprospinol: Discovery of a Steroid Drug Candidate to Treat Alzheimer’s Disease Based on 22R-Hydroxycholesterol Structure and Properties

(2011) V. Papadopoulos et al.   JOURNAL OF NEUROENDOCRINOLOGY

Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol

(2010) B. Dugas et al.   EUROPEAN JOURNAL OF NUTRITION

Oxysterols: A world to explore

(2010) A. Otaegui-Arrazola et al.   FOOD AND CHEMICAL TOXICOLOGY

Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration

(2010) Ignacio R. Rodríguez et al.   JOURNAL OF LIPID RESEARCH

Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands

(2010) P. de Medina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells

(2008) W Martinet et al.   BRITISH JOURNAL OF PHARMACOLOGY

Resistance of Young Rat Hepatic Mitochondria to Bile Acid-Induced Permeability Transition: Potential Role of α-Tocopherol

(2008) Eric Gumpricht et al.   PEDIATRIC RESEARCH