CD109 mediates tumorigenicity and cancer aggressiveness via regulation of EGFR and STAT3 signalling in cervical squamous cell carcinoma

CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro

(2019) Shufeng Zhou et al.   Scientific Reports

STAT3, stem cells, cancer stem cells and p63

(2018) Michaela Galoczova et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

CD109 and squamous cell carcinoma

(2018) Ruixia Qi et al.   Journal of Translational Medicine

Transforming Growth Factor-β-Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis

(2018) Isabel Fabregat et al.   Frontiers in Oncology

Human papillomavirus E6 protein enriches the CD55(+) population in cervical cancer cells, promoting radioresistance and cancer aggressiveness

(2017) Thomas Ho-Yin Leung et al.   JOURNAL OF PATHOLOGY

Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis

(2017) Chen-Hua Chuang et al.   NATURE MEDICINE

BRAFV600E mutation is not associated with central lymph node metastasis in all patients with papillary thyroid cancer: Different histological subtypes and preoperative lymph node status should be taken into account

(2017) Si-Yang Dong et al.   Oncology Letters

CD109 is a component of exosome secreted from cultured cells

(2016) Hiroki Sakakura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gemcitabine treatment promotes pancreatic cancer stemness through the Nox/ROS/NF-κB/STAT3 signaling cascade

(2016) Zhengle Zhang et al.   CANCER LETTERS

CD109 Mediates Cell Survival in Hepatocellular Carcinoma Cells

(2016) Guijuan Zong et al.   DIGESTIVE DISEASES AND SCIENCES

Signal Transducer and Activator of Transcription 1 (STAT1) Knock-down Induces Apoptosis in Malignant Pleural Mesothelioma

(2016) Lisa Arzt et al.   PATHOLOGY & ONCOLOGY RESEARCH

In Vitro and In Vivo Synergistic Therapeutic Effect of Cisplatin with Human Papillomavirus16 E6/E7 CRISPR/Cas9 on Cervical Cancer Cell Line

(2016) Shuai Zhen et al.   Translational Oncology

CD109 is identified as a potential nasopharyngeal carcinoma biomarker using aptamer selected by cell-SELEX

(2016) Wenting Jia et al.   Oncotarget

Reduced expression of CD109 in tumor-associated endothelial cells promotes tumor progression by paracrine interleukin-8 in hepatocellular carcinoma

(2016) Bo-Gen Ye et al.   Oncotarget

Cancer stem cells (CSCs), cervical CSCs and targeted therapies

(2016) Ruixia Huang et al.   Oncotarget

CD109 attenuates TGF-β1 signaling and enhances EGF signaling in SK-MG-1 human glioblastoma cells

(2015) Jing-Min Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CD109 is a novel marker for squamous cell/adenosquamous carcinomas of the gallbladder

(2015) Fengyun Dong et al.   Diagnostic Pathology

Prognostic impact of CD109 expression in myxofibrosarcoma

(2015) Makoto Emori et al.   JOURNAL OF SURGICAL ONCOLOGY

Elevated Expression of CD109 in Esophageal Squamous Cell Carcinoma

(2015) Fengyun Dong et al.   PATHOLOGY & ONCOLOGY RESEARCH

In vitro and in vivo growth suppression of human papillomavirus 16-positive cervical cancer cells by CRISPR/Cas9

(2014) Shuai Zhen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CD109 expression is increased in cutaneous squamous cell carcinoma

(2014) Fengyun Dong et al.   JOURNAL OF DERMATOLOGY

CD109 is a potential target for triple-negative breast cancer

(2014) Ji Tao et al.   TUMOR BIOLOGY

High Expression of CD109 Antigen Regulates the Phenotype of Cancer Stem-Like Cells/Cancer-Initiating Cells in the Novel Epithelioid Sarcoma Cell Line ESX and Is Related to Poor Prognosis of Soft Tissue Sarcoma

(2013) Makoto Emori et al.   PLoS One

Embryonic stem cell-specific signature in cervical cancer

(2013) Jorge Organista-Nava et al.   TUMOR BIOLOGY

Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance

(2012) Jacqueline López et al.   BMC CANCER

The TGF-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors

(2011) Albane A. Bizet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

CD109 release from the cell surface in human keratinocytes regulates TGF-β receptor expression, TGF-β signalling and STAT3 activation: relevance to psoriasis

(2011) Ivan V. Litvinov et al.   EXPERIMENTAL DERMATOLOGY

CD109-mediated degradation of TGF-β receptors and inhibition of TGF-β responses involve regulation of SMAD7 and Smurf2 localization and function

(2011) Albane A. Bizet et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

CD109 expression levels in malignant melanoma

(2010) Yuichiro Ohshima et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Processing of CD109 by furin and its role in the regulation of TGF-β signaling

(2010) S Hagiwara et al.   ONCOGENE

Correlation of pathological grade and tumor stage of urothelial carcinomas with CD109 expression

(2010) Minako Hagikura et al.   PATHOLOGY INTERNATIONAL

Establishment of a novel specific ELISA system for rat N- and C-ERC/mesothelin. Rat ERC/mesothelin in the body fluids of mice bearing mesothelioma

(2008) Yoshiaki Hagiwara et al.   CANCER SCIENCE