Toward heterogeneous information fusion: bipartite graph convolutional networks for in silico drug repurposing

Assessment of Use of Combined Dextromethorphan and Quinidine in Patients With Dementia or Parkinson Disease After US Food and Drug Administration Approval for Pseudobulbar Affect

(2019) Michael Fralick et al.   JAMA Internal Medicine

deepDR: A network-based deep learning approach to in silico drug repositioning

(2019) Xiangxiang Zeng et al.   BIOINFORMATICS

Publisher Correction: Network-based prediction of drug combinations

(2019) Feixiong Cheng et al.   Nature Communications

Identification of antiparkinsonian drugs in the 6-hydroxydopamine zebrafish model

(2019) Rita L. Vaz et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Modeling polypharmacy side effects with graph convolutional networks

(2018) Marinka Zitnik et al.   BIOINFORMATICS

The Effects of Thiamine on Breast Cancer Cells

(2018) Xiaowen Liu et al.   MOLECULES

Network-based approach to prediction and population-based validation of in silico drug repurposing

(2018) Feixiong Cheng et al.   Nature Communications

Bipartite graphs in systems biology and medicine: a survey of methods and applications

(2018) Georgios A Pavlopoulos et al.   GigaScience

Novel Clofarabine-Based Combinations with Polyphenols Epigenetically Reactivate Retinoic Acid Receptor Beta, Inhibit Cell Growth, and Induce Apoptosis of Breast Cancer Cells

(2018) Katarzyna Lubecka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Atomoxetine for Parkinson Disease–Related Executive Dysfunction

(2018) Carly B. Warner et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

PubChem 2019 update: improved access to chemical data

(2018) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Trial of dextromethorphan/quinidine to treat levodopa-induced dyskinesia in Parkinson's disease

(2017) Susan H. Fox et al.   MOVEMENT DISORDERS

Putting the Patient Back Together — Social Medicine, Network Medicine, and the Limits of Reductionism

(2017) Jeremy A. Greene et al.   NEW ENGLAND JOURNAL OF MEDICINE

DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

(2017) Kelsy C Cotto et al.   NUCLEIC ACIDS RESEARCH

A standard database for drug repositioning

(2017) Adam S. Brown et al.   Scientific Data

Arsenic trioxide suppresses cell growth and migration via inhibition of miR-27a in breast cancer cells

(2016) Shunhua Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Drug repositioning based on comprehensive similarity measures and Bi-Random walk algorithm

(2016) Huimin Luo et al.   BIOINFORMATICS

Atomoxetine restores the response inhibition network in Parkinson’s disease

(2016) Charlotte L. Rae et al.   BRAIN

Network analysis of genes and their association with diseases

(2016) Panagiota I. Kontou et al.   GENE

Molecular graph convolutions: moving beyond fingerprints

(2016) Steven Kearnes et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

(2016) Duncan E. Scott et al.   NATURE REVIEWS DRUG DISCOVERY

DrugCentral: online drug compendium

(2016) Oleg Ursu et al.   NUCLEIC ACIDS RESEARCH

DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants

(2016) Janet Piñero et al.   NUCLEIC ACIDS RESEARCH

The Comparative Toxicogenomics Database: update 2017

(2016) Allan Peter Davis et al.   NUCLEIC ACIDS RESEARCH

Trajectories of recovery in depressed Parkinson's disease patients treated with paroxetine or venlafaxine

(2016) M.P.G. Broen et al.   PARKINSONISM & RELATED DISORDERS

Network-based in silico drug efficacy screening

(2016) Emre Guney et al.   Nature Communications

Improving Response Inhibition in Parkinson’s Disease with Atomoxetine

(2015) Zheng Ye et al.   BIOLOGICAL PSYCHIATRY

A survey of current trends in computational drug repositioning

(2015) Jiao Li et al.   BRIEFINGS IN BIOINFORMATICS

Randomized, controlled pilot trial of solifenacin succinate for overactive bladder in Parkinson's disease

(2015) Theresa A. Zesiewicz et al.   PARKINSONISM & RELATED DISORDERS

Uncovering disease-disease relationships through the incomplete interactome

(2015) J. Menche et al.   SCIENCE

Construction of Drug Network Based on Side Effects and Its Application for Drug Repositioning

(2014) Hao Ye et al.   PLoS One

Clofarabine, a novel adenosine analogue, reactivates DNA methylation-silenced tumour suppressor genes and inhibits cell growth in breast cancer cells

(2013) Katarzyna Lubecka-Pietruszewska et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Drug Repositioning: A Machine-Learning Approach through Data Integration

(2013) Francesco Napolitano et al.   Journal of Cheminformatics

Predicting New Indications for Approved Drugs Using a Proteochemometric Method

(2012) Sivanesan Dakshanamurthy et al.   JOURNAL OF MEDICINAL CHEMISTRY

Use of genome-wide association studies for drug repositioning

(2012) Philippe Sanseau et al.   NATURE BIOTECHNOLOGY

PREDICT: a method for inferring novel drug indications with application to personalized medicine

(2011) A. Gottlieb et al.   Molecular Systems Biology

The Graph Neural Network Model

(2008) F. Scarselli et al.   IEEE TRANSACTIONS ON NEURAL NETWORKS