Cancer mutational signatures representation by large-scale context embedding

Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences

(2020) Sushant Kumar et al.   CELL

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

(2020) Wei Jiao et al.   Nature Communications

Local Determinants of the Mutational Landscape of the Human Genome

(2019) Abel Gonzalez-Perez et al.   CELL

A Compendium of Mutational Signatures of Environmental Agents

(2019) Jill E. Kucab et al.   CELL

Passenger mutations accurately classify human tumors

(2019) Marina Salvadores et al.   PLoS Computational Biology

BindSpace decodes transcription factor binding signals by large-scale sequence embedding

(2019) Han Yuan et al.   NATURE METHODS

Recurrent somatic mutations reveal new insights into consequences of mutagenic processes in cancer

(2019) Miranda D. Stobbe et al.   PLoS Computational Biology

Cancer subtype identification using somatic mutation data

(2018) Marieke Lydia Kuijjer et al.   BRITISH JOURNAL OF CANCER

Whole-genome landscapes of major melanoma subtypes

(2017) Nicholas K. Hayward et al.   NATURE

Mutational signatures associated with tobacco smoking in human cancer

(2016) L. B. Alexandrov et al.   SCIENCE

Genomic Classification of Cutaneous Melanoma

(2015) Rehan Akbani et al.   CELL

The somatic autosomal mutation matrix in cancer genomes

(2015) Nuri A. Temiz et al.   HUMAN GENETICS

Cell-of-origin chromatin organization shapes the mutational landscape of cancer

(2015) Paz Polak et al.   NATURE

Somatic mutation in cancer and normal cells

(2015) I. Martincorena et al.   SCIENCE

A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures

(2015) Yuichi Shiraishi et al.   PLoS Genetics

Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin

(2014) Katherine A. Hoadley et al.   CELL

UV Signature Mutations

(2014) Douglas E. Brash   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Emerging patterns of somatic mutations in cancer

(2013) Ian R. Watson et al.   NATURE REVIEWS GENETICS

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Chromatin organization is a major influence on regional mutation rates in human cancer cells

(2012) Benjamin Schuster-Böckler et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Human mutation rate associated with DNA replication timing

(2009) John A Stamatoyannopoulos et al.   NATURE GENETICS