Phosphorothioate Modification of mRNA Accelerates the Rate of Translation Initiation to Provide More Efficient Protein Synthesis
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Phosphorothioate Modification of mRNA Accelerates the Rate of Translation Initiation to Provide More Efficient Protein Synthesis
Authors
Keywords
-
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-07-06
DOI
10.1002/anie.202007111
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery
- (2019) Piotr S. Kowalski et al. MOLECULAR THERAPY
- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- Decoding on the ribosome depends on the structure of the mRNA phosphodiester backbone
- (2018) Hannah E. Keedy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unlocking P(V): Reagents for chiral phosphorothioate synthesis
- (2018) Kyle W. Knouse et al. SCIENCE
- Therapeutic Oligonucleotides: State of the Art
- (2018) C.I. Edvard Smith et al. Annual Review of Pharmacology and Toxicology
- The stop and go traffic regulating protein biogenesis: how translation kinetics control proteostasis
- (2018) Kevin C. Stein et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- mRNA-Based Protein Replacement Therapy for the Heart
- (2018) Ajit Magadum et al. MOLECULAR THERAPY
- The chemical evolution of oligonucleotide therapies of clinical utility
- (2017) Anastasia Khvorova et al. NATURE BIOTECHNOLOGY
- Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
- (2017) Naoki Iwamoto et al. NATURE BIOTECHNOLOGY
- Effects of Chemically Modified Messenger RNA on Protein Expression
- (2016) Bin Li et al. BIOCONJUGATE CHEMISTRY
- Molecular insights into protein synthesis with proline residues
- (2016) Sergey Melnikov et al. EMBO REPORTS
- Differential Scanning Fluorimetry for Monitoring RNA Stability
- (2015) Robert Silvers et al. CHEMBIOCHEM
- Secondary Structure across the Bacterial Transcriptome Reveals Versatile Roles in mRNA Regulation and Function
- (2015) Cristian Del Campo et al. PLoS Genetics
- Screening of mRNA Chemical Modification to Maximize Protein Expression with Reduced Immunogenicity
- (2015) Satoshi Uchida et al. Pharmaceutics
- Phosphorothioates, Essential Components of Therapeutic Oligonucleotides
- (2014) Fritz Eckstein Nucleic Acid Therapeutics
- Stereocontrolled Solid-Phase Synthesis of Phosphorothioate Oligoribonucleotides Using 2′-O-(2-Cyanoethoxymethyl)-nucleoside 3′-O-Oxazaphospholidine Monomers
- (2012) Yohei Nukaga et al. JOURNAL OF ORGANIC CHEMISTRY
- Stereocontrolled synthesis of oligonucleotide analogs containing chiral internucleotidic phosphorus atoms
- (2011) Natsuhisa Oka et al. CHEMICAL SOCIETY REVIEWS
- Ribosomal Translocation: One Step Closer to the Molecular Mechanism
- (2009) Shinichiro Shoji et al. ACS Chemical Biology
- Stereocontrolled Synthesis of Oligoribonucleoside Phosphorothioates by an Oxazaphospholidine Approach
- (2009) Natsuhisa Oka et al. ORGANIC LETTERS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation