Biofilm propensity of Staphylococcus aureus skin isolates is associated with increased atopic dermatitis severity and barrier dysfunction in the MPAACH pediatric cohort

Simultaneous skin biome and keratinocyte genomic capture reveals microbiome differences by depth of sampling

(2020) Mariana L. Stevens et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Events in Normal Skin Promote Early-Life Atopic Dermatitis—The MPAACH Cohort

(2020) Jocelyn M. Biagini Myers et al.   Journal of Allergy and Clinical Immunology-In Practice

Microbial guardians of skin health

(2019) Apollo Stacy et al.   SCIENCE

The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype

(2019) Donald Y. M. Leung et al.   Science Translational Medicine

Identification of two early life eczema and non‐eczema phenotypes with high risk for asthma development

(2019) Elisabet Johansson et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Patients with Atopic Dermatitis Colonized with Staphylococcus aureus Have a Distinct Phenotype and Endotype

(2018) Eric L. Simpson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Inflammatory cytokines and biofilm production sustain Staphylococcus aureus outgrowth and persistence: a pivotal interplay in the pathogenesis of Atopic Dermatitis

(2018) E. G. Di Domenico et al.   Scientific Reports

Human skin commensals augment Staphylococcus aureus pathogenesis

(2018) Emma Boldock et al.   Nature Microbiology

Relations between epidermal barrier dysregulation and Staphylococcus species–dominated microbiome dysbiosis in patients with atopic dermatitis

(2018) Can Altunbulakli et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury

(2018) Oliver J. Harrison et al.   SCIENCE

Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year

(2017) Elizabeth A. Kennedy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Staphylococcus aureus Induces Increased Serine Protease Activity in Keratinocytes

(2017) Michael R. Williams et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Skin Colonization by Staphylococcus aureus Precedes the Clinical Diagnosis of Atopic Dermatitis in Infancy

(2017) Patrick Meylan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Defining the metal specificity of a multifunctional biofilm adhesion protein

(2017) Catherine T. Chaton et al.   PROTEIN SCIENCE

Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis

(2017) Teruaki Nakatsuji et al.   Science Translational Medicine

Identification of bacterial biofilm and the Staphylococcus aureus derived protease, staphopain, on the skin surface of patients with atopic dermatitis

(2017) Andreas Sonesson et al.   Scientific Reports

Functional consequences of B-repeat sequence variation in the staphylococcal biofilm protein Aap: deciphering the assembly code

(2016) Catherine L. Shelton et al.   BIOCHEMICAL JOURNAL

Bacterial and Viral Infections in Atopic Dermatitis: a Comprehensive Review

(2016) Peck Y. Ong et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

The Pathogenetic Effect of Natural and Bacterial Toxins on Atopic Dermatitis

(2016) Kyung-Duck Park et al.   Toxins

The Role of the Skin Microbiome in Atopic Dermatitis

(2015) Michael R. Williams et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis

(2015) Tetsuro Kobayashi et al.   IMMUNITY

Staphlyococcus aureus Phenol-Soluble Modulins Stimulate the Release of Proinflammatory Cytokines from Keratinocytes and Are Required for Induction of Skin Inflammation

(2015) Adnan K. Syed et al.   INFECTION AND IMMUNITY

Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year

(2015) Maeve Kelleher et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Nutritional Immunity: S100 Proteins at the Host-Pathogen Interface

(2015) Joseph P. Zackular et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits ExtracellularAspergillus fumigatusHyphal Growth and Corneal Infection

(2015) Heather L. Clark et al.   JOURNAL OF IMMUNOLOGY

Commensal–dendritic-cell interaction specifies a unique protective skin immune signature

(2015) Shruti Naik et al.   NATURE

Zinc-dependent mechanical properties ofStaphylococcus aureusbiofilm-forming surface protein SasG

(2015) Cécile Formosa-Dague et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin

(2015) Tyler D. Scherr et al.   mBio

Reduced filaggrin expression is accompanied by increasedStaphylococcus aureuscolonization of epidermal skin models

(2014) V. van Drongelen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Skin Barrier Defects in Atopic Dermatitis

(2014) Rachana Agrawal et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Staphylococcus epidermidis agr Quorum-Sensing System: Signal Identification, Cross Talk, and Importance in Colonization

(2014) M. E. Olson et al.   JOURNAL OF BACTERIOLOGY

Th2 Cytokines Increase Staphylococcus aureus Alpha Toxin–Induced Keratinocyte Death through the Signal Transducer and Activator of Transcription 6 (STAT6)

(2014) Anne M. Brauweiler et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dialogue between skin microbiota and immunity

(2014) Y. Belkaid et al.   SCIENCE

Proteases: common culprits in human skin disorders

(2014) Simon J. de Veer et al.   TRENDS IN MOLECULAR MEDICINE

The Presence and Impact of Biofilm-Producing Staphylococci in Atopic Dermatitis

(2014) Herbert B. Allen et al.   JAMA Dermatology

Hiding in Plain Sight: Interplay between Staphylococcal Biofilms and Host Immunity

(2014) Tyler D. Scherr et al.   Frontiers in Immunology

Validation of a Parental Questionnaire to Identify Atopic Dermatitis in a Population-Based Sample of Children up to 2 Years of Age

(2013) L.B. von Kobyletzki et al.   DERMATOLOGY

Staphylococcus δ-toxin induces allergic skin disease by activating mast cells

(2013) Yuumi Nakamura et al.   NATURE

Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms

(2013) D. G. Conrady et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens

(2013) S. M. Damo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis

(2012) H. H. Kong et al.   GENOME RESEARCH

Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice

(2012) Hiroshi Kawasaki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

How Staphylococcus aureus biofilms develop their characteristic structure

(2012) S. Periasamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel finding in atopic dermatitis: film-producing Staphylococcus epidermidis as an etiology

(2011) Herbert B. Allen et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Staphylococcus aureus Biofilms Prevent Macrophage Phagocytosis and Attenuate Inflammation In Vivo

(2011) L. R. Thurlow et al.   JOURNAL OF IMMUNOLOGY

Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus

(2010) Helen Miajlovic et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Role of Surface Protein SasG in Biofilm Formation by Staphylococcus aureus

(2010) J. A. Geoghegan et al.   JOURNAL OF BACTERIOLOGY

Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization

(2010) Tadayuki Iwase et al.   NATURE

Isolation of α-toxin-producingStaphylococcus aureusfrom the skin of highly sensitized adult patients with severe atopic dermatitis

(2009) K. Wichmann et al.   BRITISH JOURNAL OF DERMATOLOGY

Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen

(2009) Michiko K. Oyoshi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Selective Antimicrobial Action Is Provided by Phenol-Soluble Modulins Derived from Staphylococcus epidermidis, a Normal Resident of the Skin

(2009) Anna L. Cogen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Intrinsically defective skin barrier function in children with atopic dermatitis correlates with disease severity

(2008) Jayanta Gupta et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support

(2008) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Atopic Dermatitis

(2008) Thomas Bieber   NEW ENGLAND JOURNAL OF MEDICINE

A zinc-dependent adhesion module is responsible for intercellular adhesion in staphylococcal biofilms

(2008) D. G. Conrady et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

(2008) Brian D. Corbin et al.   SCIENCE

agr-Mediated Dispersal of Staphylococcus aureus Biofilms

(2008) Blaise R. Boles et al.   PLoS Pathogens