The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype

Cytokine modulation of atopic itch

(2018) Anna M Trier et al.   CURRENT OPINION IN IMMUNOLOGY

Mechanism for initiation of food allergy: Dependence on skin barrier mutations and environmental allergen costimulation

(2018) Matthew T. Walker et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Predicting the atopic march: Results from the Canadian Healthy Infant Longitudinal Development Study

(2018) Maxwell M. Tran et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Minimally invasive skin tape strip RNA sequencing identifies novel characteristics of the type 2–high atopic dermatitis disease endotype

(2018) Nathan Dyjack et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Patients with Atopic Dermatitis Colonized with Staphylococcus aureus Have a Distinct Phenotype and Endotype

(2018) Eric L. Simpson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Graphic depiction of bioinformatics data

(2017) Agustin Calatroni et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year

(2017) Elizabeth A. Kennedy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Novel concepts of prevention and treatment of atopic dermatitis through barrier and immune manipulations with implications for the atopic march

(2017) Tali Czarnowicki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Staphylococcus aureus Induces Increased Serine Protease Activity in Keratinocytes

(2017) Michael R. Williams et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Skin Colonization by Staphylococcus aureus Precedes the Clinical Diagnosis of Atopic Dermatitis in Infancy

(2017) Patrick Meylan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis

(2017) Teruaki Nakatsuji et al.   Science Translational Medicine

Epidermal thymic stromal lymphopoietin predicts the development of atopic dermatitis during infancy

(2016) Jihyun Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis—PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology

(2016) Antonella Muraro et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Skin barrier impairment at birth predicts food allergy at 2 years of age

(2016) Maeve M. Kelleher et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Food allergy is associated with Staphylococcus aureus colonization in children with atopic dermatitis

(2016) Andrea L. Jones et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Staphylococcus aureus Exploits Epidermal Barrier Defects in Atopic Dermatitis to Trigger Cytokine Expression

(2016) Teruaki Nakatsuji et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

(2016) Eric L. Simpson et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy

(2016) Boyi Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What the Eczema Area and Severity Index score tells us about the severity of atopic dermatitis: an interpretability study

(2015) Y.A. Leshem et al.   BRITISH JOURNAL OF DERMATOLOGY

Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis

(2015) Tetsuro Kobayashi et al.   IMMUNITY

Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year

(2015) Maeve Kelleher et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

(2015) Helen A. Brough et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Networks of energetic and metabolic interactions define dynamics in microbial communities

(2015) Mallory Embree et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

qgraph: Network Visualizations of Relationships in Psychometric Data

(2015) Sacha Epskamp et al.   Journal of Statistical Software

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Mechanisms of abnormal lamellar body secretion and the dysfunctional skin barrier in patients with atopic dermatitis

(2014) Peter M. Elias et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis

(2014) Jacob P. Thyssen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis

(2014) Jennifer D. Hamilton et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Peanut allergy: Effect of environmental peanut exposure in children with filaggrin loss-of-function mutations

(2014) Helen A. Brough et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Skin exposure promotes a Th2-dependent sensitization to peanut allergens

(2014) Leticia Tordesillas et al.   JOURNAL OF CLINICAL INVESTIGATION

Emerging therapies for food allergy

(2014) Corinne A. Keet et al.   JOURNAL OF CLINICAL INVESTIGATION

Knockdown of Filaggrin in a Three-Dimensional Reconstructed Human Epidermis Impairs Keratinocyte Differentiation

(2014) Valérie Pendaries et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis

(2014) Lisa A. Beck et al.   NEW ENGLAND JOURNAL OF MEDICINE

Assessment of Pruritus Intensity: Prospective Study on Validity and Reliability of the Visual Analogue Scale, Numerical Rating Scale and Verbal Rating Scale in 471 Patients with Chronic Pruritus

(2013) N Phan et al.   ACTA DERMATO-VENEREOLOGICA

Filaggrin Deficiency Leads to Impaired Lipid Profile and Altered Acidification Pathways in a 3D Skin Construct

(2013) Kateřina Vávrová et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Atopic Dermatitis and Disease Severity Are the Main Risk Factors for Food Sensitization in Exclusively Breastfed Infants

(2013) Carsten Flohr et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

In Vitro Assessment of IL-4- or IL-13-Mediated Changes in the Structural Components of Keratinocytes in Mice and Humans

(2013) Miyuki Omori-Miyake et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Keratin 16 regulates innate immunity in response to epidermal barrier breach

(2013) J. C. Lessard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid, simultaneous and nanomolar determination of pyroglutamic acid and cis-/trans-urocanic acid in human stratum corneum by hydrophilic interaction liquid chromatography (HILIC)–electrospray ionization tandem mass spectrometry

(2012) Kyung-Mi Joo et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Cellular Changes that Accompany Shedding of Human Corneocytes

(2012) Tzu-Kai Lin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity

(2011) S. Kezic et al.   ALLERGY

Filaggrin Genotype in Ichthyosis Vulgaris Predicts Abnormalities in Epidermal Structure and Function

(2011) Robert Gruber et al.   AMERICAN JOURNAL OF PATHOLOGY

Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy

(2011) Sara J. Brown et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Comparative proteomic profiling of patients with atopic dermatitis based on history of eczema herpeticum infection and Staphylococcus aureus colonization

(2011) Carolyn J. Broccardo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Filaggrin Mutations Associated with Skin and Allergic Diseases

(2011) Alan D. Irvine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanical injury polarizes skin dendritic cells to elicit a TH2 response by inducing cutaneous thymic stromal lymphopoietin expression

(2010) Michiko K. Oyoshi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Phenotype of atopic dermatitis subjects with a history of eczema herpeticum

(2009) Lisa A. Beck et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia

(2009) Hermann H. Bragulla et al.   JOURNAL OF ANATOMY

Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6

(2008) Byung Eui Kim et al.   CLINICAL IMMUNOLOGY