Metabolic Fingerprinting with Fourier-Transform Infrared (FTIR) Spectroscopy: Towards a High-Throughput Screening Assay for Antibiotic Discovery and Mechanism-of-Action Elucidation

Tracking of single tRNAs for translation kinetics measurements in chloramphenicol treated bacteria

(2019) Ivan L. Volkov et al.   METHODS

Metabolomics-Driven Exploration of the Chemical Drug Space to Predict Combination Antimicrobial Therapies

(2019) Adrian I. Campos et al.   MOLECULAR CELL

Folic Acid Antagonists: Antimicrobial and Immunomodulating Mechanisms and Applications

(2019) Fernández-Villa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A phenotypic screening bioassay for Escherichia coli stress and antibiotic responses based on Fourier‐transform infrared (FTIR) spectroscopy and multivariate analysis

(2019) B. Ribeiro da Cunha et al.   JOURNAL OF APPLIED MICROBIOLOGY

Comparative proteomic analysis of Escherichia coli O157:H7 following ohmic and water bath heating by capillary-HPLC-MS/MS

(2018) Xiaojing Tian et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds

(2018) Mattia Zampieri et al.   Science Translational Medicine

Characterization of gastric cells infection by diverse Helicobacter pylori strains through Fourier-transform infrared spectroscopy

(2018) Vanda Marques et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Challenges, progress and promises of metabolite annotation for LC–MS-based metabolomics

(2018) Romanas Chaleckis et al.   CURRENT OPINION IN BIOTECHNOLOGY

Detection of molecular changes induced by antibiotics in Escherichia coli using vibrational spectroscopy

(2017) N.T. Xuan Nguyen et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Antimicrobial Activity and Resistance: Influencing Factors

(2017) Jun Li et al.   Frontiers in Pharmacology

Comparative metabolomics revealing Staphylococcus aureus metabolic response to different antibiotics

(2017) Katie Schelli et al.   Microbial Biotechnology

Dimethyl Sulfoxide Protects Escherichia coli from Rapid Antimicrobial-Mediated Killing

(2016) Hongfei Mi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Untargeted Metabolomics To Ascertain Antibiotic Modes of Action

(2016) Isabel M. Vincent et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics

(2016) Verena Hoerr et al.   BMC MICROBIOLOGY

Overview on mechanisms of isoniazid action and resistance in Mycobacterium tuberculosis

(2016) Ameeruddin Nusrath Unissa et al.   INFECTION GENETICS AND EVOLUTION

Metabolic profiling as a tool for prioritizing antimicrobial compounds

(2015) Changsheng Wu et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Integration of high-content screening and untargeted metabolomics for comprehensive functional annotation of natural product libraries

(2015) Kenji L. Kurita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage

(2015) Peter Belenky et al.   Cell Reports

Beta-Lactam Antibiotics Induce a Lethal Malfunctioning of the Bacterial Cell Wall Synthesis Machinery

(2014) Hongbaek Cho et al.   CELL

Partial least squares discriminant analysis: taking the magic away

(2014) Richard G. Brereton et al.   JOURNAL OF CHEMOMETRICS

Sequence selectivity of macrolide-induced translational attenuation

(2014) A. R. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimizing Savitzky–Golay Parameters for Improving Spectral Resolution and Quantification in Infrared Spectroscopy

(2013) Boris Zimmermann et al.   APPLIED SPECTROSCOPY

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules

(2013) P. Nonejuie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aminoglycoside Antibiotics in the 21st Century

(2012) Bernd Becker et al.   ACS Chemical Biology

Spectral pre-processing for biomedical vibrational spectroscopy and microspectroscopic imaging

(2012) Peter Lasch   CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS

Chemoproteomic approaches to drug target identification and drug profiling

(2011) Marcus Bantscheff et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Exometabolome Analysis Identifies Pyruvate Dehydrogenase as a Target for the Antibiotic Triphenylbismuthdichloride in Multiresistant Bacterial Pathogens

(2011) Timo Birkenstock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monitoring the Effects of Chiral Pharmaceuticals on Aquatic Microorganisms by Metabolic Fingerprinting

(2010) E. S. Wharfe et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biochemical Target Isolation for Novices: Affinity-Based Strategies

(2010) Shin-ichi Sato et al.   CHEMISTRY & BIOLOGY

Metronidazole Is Still the Drug of Choice for Treatment of Anaerobic Infections

(2010) Sonja Löfmark et al.   CLINICAL INFECTIOUS DISEASES

Stalled replication fork repair and misrepair during thymineless death in Escherichia coli

(2010) Kawai J Kuong et al.   GENES TO CELLS

How antibiotics kill bacteria: from targets to networks

(2010) Michael A. Kohanski et al.   NATURE REVIEWS MICROBIOLOGY

Discovery of drug mode of action and drug repositioning from transcriptional responses

(2010) F. Iorio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loopy MSC: A Simple Way to Improve Multiplicative Scatter Correction

(2009) Willem Windig et al.   APPLIED SPECTROSCOPY

The use of FTIR microscopy for the evaluation of anti-bacterial agents activity

(2009) Mahmoud Huleihel et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

An explanation for the effect of inoculum size on MIC and the growth/no growth interface

(2008) E BIDLAS et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY