Ivermectin Inhibits Bovine Herpesvirus 1 DNA Polymerase Nuclear Import and Interferes With Viral Replication

The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer

(2020) Sundy N.Y. Yang et al.   ANTIVIRAL RESEARCH

Intersectin goes nuclear: secret life of an endocytic protein

(2018) Gualtiero Alvisi et al.   BIOCHEMICAL JOURNAL

The cellular coactivator HCF-1 is required for glucocorticoid receptor-mediated transcription of bovine herpesvirus 1 immediate early genes

(2018) Laximan Sawant et al.   JOURNAL OF VIROLOGY

The Wnt Signaling Pathway Is Differentially Expressed during the Bovine Herpesvirus 1 Latency-Reactivation Cycle: Evidence That Two Protein Kinases Associated with Neuronal Survival, Akt3 and BMPR2, Are Expressed at Higher Levels during Latency

(2018) Aspen Workman et al.   JOURNAL OF VIROLOGY

Ivermectin inhibits DNA polymerase UL42 of pseudorabies virus entrance into the nucleus and proliferation of the virus in vitro and vivo

(2018) Changjie Lv et al.   ANTIVIRAL RESEARCH

Antivirus effectiveness of ivermectin on dengue virus type 2 in Aedes albopictus

(2018) Tie-Long Xu et al.   PLoS Neglected Tropical Diseases

Combinatorial Effects of the Glucocorticoid Receptor and Krüppel-Like Transcription Factor 15 on Bovine Herpesvirus 1 Transcription and Productive Infection

(2017) Fouad S. El-mayet et al.   JOURNAL OF VIROLOGY

Bovine herpesvirus 1 tegument protein UL21 plays critical roles in viral secondary envelopment and cell-to-cell spreading

(2017) Farzana Shahin et al.   Oncotarget

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

(2016) Nicholas J. Barrows et al.   Cell Host & Microbe

Potential Role for a β-Catenin Coactivator (High-Mobility Group AT–Hook 1 Protein) during the Latency-Reactivation Cycle of Bovine Herpesvirus 1

(2016) Liqian Zhu et al.   JOURNAL OF VIROLOGY

Effectiveness of a BHV-1/BEFV bivalent vaccine against bovine herpesvirus type 1 infection in cattle

(2016) Yao-Chi Chung et al.   RESEARCH IN VETERINARY SCIENCE

A bovine herpesvirus 1 pUL51 deletion mutant shows impaired viral growth in vitro and reduced virulence in rabbits

(2016) Sohail Raza et al.   Oncotarget

Antiviral activity of theaflavin digallate against herpes simplex virus type 1

(2015) Aline de Oliveira et al.   ANTIVIRAL RESEARCH

Profile of William C. Campbell, Satoshi Ōmura, and Youyou Tu, 2015 Nobel Laureates in Physiology or Medicine

(2015) Wesley C. Van Voorhis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of black tea extract on herpes simplex virus-1 infection of cultured cells

(2013) Anthony Cantatore et al.   BMC Complementary and Alternative Medicine

Bovine Herpesvirus 1 Regulatory Proteins bICP0 and VP16 Are Readily Detected in Trigeminal Ganglionic Neurons Expressing the Glucocorticoid Receptor during the Early Stages of Reactivation from Latency

(2013) L. Frizzo da Silva et al.   JOURNAL OF VIROLOGY

Nuclear Transport of Epstein-Barr Virus DNA Polymerase Is Dependent on the BMRF1 Polymerase Processivity Factor and Molecular Chaperone Hsp90

(2013) D. Kawashima et al.   JOURNAL OF VIROLOGY

A Cutting-Edge View on the Current State of Antiviral Drug Development

(2013) Erik De Clercq   MEDICINAL RESEARCH REVIEWS

Regulated Transport into the Nucleus of Herpesviridae DNA Replication Core Proteins

(2013) Gualtiero Alvisi et al.   Viruses-Basel

Immunity to Bovine Herpesvirus 1: I. Viral lifecycle and innate immunity

(2013) Randall L. Levings et al.   ANIMAL HEALTH RESEARCH REVIEWS

Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus

(2012) Kylie M. Wagstaff et al.   BIOCHEMICAL JOURNAL

Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug

(2012) E. Mastrangelo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Multiple phosphorylation sites at the C-terminus regulate nuclear import of HCMV DNA polymerase processivity factor ppUL44

(2011) Gualtiero Alvisi et al.   VIROLOGY

Ivermectin effects on motor coordination and contractions of isolated rat diaphragm

(2010) Sasa M. Trailovic et al.   RESEARCH IN VETERINARY SCIENCE

The Flexible Loop of the Human Cytomegalovirus DNA Polymerase Processivity Factor ppUL44 Is Required for Efficient DNA Binding and Replication in Cells

(2009) G. Alvisi et al.   JOURNAL OF VIROLOGY

Nuclear Import of HSV-1 DNA Polymerase Processivity Factor UL42 Is Mediated by a C-Terminally Located Bipartite Nuclear Localization Signal†

(2008) Gualtiero Alvisi et al.   BIOCHEMISTRY

Six Classes of Nuclear Localization Signals Specific to Different Binding Grooves of Importin α

(2008) Shunichi Kosugi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY