Protein Formulations Containing Polysorbates: Are Metal Chelators Needed at All?
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Protein Formulations Containing Polysorbates: Are Metal Chelators Needed at All?
Authors
Keywords
-
Journal
Antioxidants
Volume 9, Issue 5, Pages 441
Publisher
MDPI AG
Online
2020-05-20
DOI
10.3390/antiox9050441
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Factors influencing polysorbate’s sensitivity against enzymatic hydrolysis and oxidative degradation
- (2019) Wendelin Kranz et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Biological Evaluation of 8-Hydroxyquinolines as Multi-Target Directed Ligands for Treating Alzheimer’s Disease
- (2019) Damijan Knez et al. Current Alzheimer Research
- Iron-Binding and Anti-Fenton Properties of Novel Amino Acid-Derived Cyclic Imide Dioximes
- (2019) Janez Mravljak et al. Antioxidants
- Novel markers to track oxidative polysorbate degradation in pharmaceutical formulations
- (2018) Sanket Dahotre et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Trends on Analytical Characterization of Polysorbates and Their Degradation Products in Biopharmaceutical Formulations
- (2017) Ariadna Martos et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Protein oxidation and peroxidation
- (2016) M. J. Davies BIOCHEMICAL JOURNAL
- Degradation Mechanisms of Polysorbate 20 Differentiated by 18O-labeling and Mass Spectrometry
- (2016) Lin Zhang et al. PHARMACEUTICAL RESEARCH
- Oxidative Degradation of Polysorbate Surfactants Studied by Liquid Chromatography–Mass Spectrometry
- (2015) Oleg V. Borisov et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol
- (2014) Fei Mao et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Influence of methionine oxidation on the aggregation of recombinant human growth hormone
- (2013) Filippo Mulinacci et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Oxidation of Therapeutic Proteins and Peptides: Structural and Biological Consequences
- (2013) Riccardo Torosantucci et al. PHARMACEUTICAL RESEARCH
- Effect of Polysorbate 80 Quality on Photostability of a Monoclonal Antibody
- (2012) Swita R. Singh et al. AAPS PHARMSCITECH
- An N-Heterocyclic Amine Chelate Capable of Antioxidant Capacity and Amyloid Disaggregation
- (2012) Kimberly M. Lincoln et al. ACS Chemical Neuroscience
- Simultaneous Detection of Low and High Molecular Weight Carbonylated Compounds Derived from Lipid Peroxidation by Electrospray Ionization-Tandem Mass Spectrometry
- (2012) Ivana Milic et al. ANALYTICAL CHEMISTRY
- Biologics Formulation Factors Affecting Metal Leachables from Stainless Steel
- (2011) Shuxia Zhou et al. AAPS PHARMSCITECH
- The Degradation of Polysorbates 20 and 80 and its Potential Impact on the Stability of Biotherapeutics
- (2011) Ravuri S. K. Kishore et al. PHARMACEUTICAL RESEARCH
- Fast and sensitive determination of Polysorbate 80 in solutions containing proteins
- (2010) Szabolcs Fekete et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Comparative Evaluation of Disodium Edetate and Diethylenetriaminepentaacetic Acid as Iron Chelators to Prevent Metal -Catalyzed Destabilization of a Therapeutic Monoclonal Antibody
- (2010) Shuxia Zhou et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Degradation of Polysorbates 20 and 80: Studies on Thermal Autoxidation and Hydrolysis
- (2010) Ravuri S.K. Kishore et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- In vitro methionine oxidation of escherichia coli-derived human stem cell factor: Effects on the molecular structure, biological activity, and dimerization
- (2010) Yueh-Rong Hsu et al. PROTEIN SCIENCE
- Methionine, tryptophan, and histidine oxidation in a model protein, PTH: Mechanisms and stabilization
- (2009) Junyan A. Ji et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A Quantitative Kinetic Study of Polysorbate Autoxidation: The Role of Unsaturated Fatty Acid Ester Substituents
- (2009) Jia Yao et al. PHARMACEUTICAL RESEARCH
- Polysorbates 20 and 80 Used in the Formulation of Protein Biotherapeutics: Structure and Degradation Pathways
- (2007) Bruce A. Kerwin JOURNAL OF PHARMACEUTICAL SCIENCES
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started