Causal associations of insulin resistance with coronary artery disease and ischemic stroke: a Mendelian randomization analysis

Mendelian Randomization Study of Obesity and Cerebrovascular Disease

(2020) Sandro Marini et al.   ANNALS OF NEUROLOGY

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

Causal Impact of Type 2 Diabetes Mellitus on Cerebral Small Vessel Disease

(2018) Junfeng Liu et al.   STROKE

An introduction to Mendelian randomization with applications in neurology

(2018) Phillip H. Allman et al.   Multiple Sclerosis and Related Disorders

‘Mendelian randomization’: an approach for exploring causal relations in epidemiology

(2017) V. Gupta et al.   PUBLIC HEALTH

Genetic support for the causal role of insulin in coronary heart disease

(2016) Emmi Tikkanen et al.   DIABETOLOGIA

Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank

(2016) Wei Gan et al.   DIABETOLOGIA

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic

(2016) Jack Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

(2016) Luca A Lotta et al.   NATURE GENETICS

Pioglitazone after Ischemic Stroke or Transient Ischemic Attack

(2016) Walter N. Kernan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Insulin Resistance Is a Risk Factor for Silent Lacunar Infarction

(2016) Ji Eun Lee et al.   STROKE

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

(2016) Bram. P. Prins et al.   PLOS MEDICINE

Insulin Resistance and Risk of Cardiovascular Disease in Postmenopausal Women: A Cohort Study From the Women's Health Initiative

(2015) M. D. Schmiegelow et al.  

Mendelian randomization analysis supports the causal role of dysglycaemia and diabetes in the risk of coronary artery disease

(2015) Stephanie Ross et al.   EUROPEAN HEART JOURNAL

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

(2015) Joshua W. Knowles et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Insulin Resistance and Risk of Cardiovascular Disease in Postmenopausal Women: A Cohort Study From the Women's Health Initiative

(2015) M. D. Schmiegelow et al.   Circulation-Cardiovascular Quality and Outcomes

Genetic Evidence for a Normal-Weight "Metabolically Obese" Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes

(2014) H. Yaghootkar et al.   DIABETES

Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity

(2014) R. A. Scott et al.   DIABETES

Racial Differences in the Association of Insulin Resistance With Stroke Risk

(2014) George Howard et al.   STROKE

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Insulin Resistance and the Risk of Stroke and Stroke Subtypes in the Nondiabetic Elderly

(2012) R. G. Wieberdink et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

(2012) Robert A Scott et al.   NATURE GENETICS

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

(2012) Alisa K Manning et al.   NATURE GENETICS

Fasting and Post-Glucose Load Measures of Insulin Resistance and Risk of Ischemic Stroke in Older Adults

(2011) Evan L. Thacker et al.   STROKE

Insulin Resistance and Risk of Ischemic Stroke Among Nondiabetic Individuals From the Northern Manhattan Study

(2010) Tatjana Rundek et al.   ARCHIVES OF NEUROLOGY

Correlation Between Insulin Resistance and Intracranial Atherosclerosis in Patients With Ischemic Stroke Without Diabetes

(2008) Hyun-Young Park et al.   Journal of Stroke & Cerebrovascular Diseases

Insulin Resistance as a Risk Factor for Carotid Atherosclerosis

(2008) Harald Sourij et al.   STROKE

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE