Intestine-Liver Axis On-Chip Reveals the Intestinal Protective Role on Hepatic Damage by Emulating Ethanol First-Pass Metabolism

Intestine‐on‐chip device increases ECM remodeling inducing faster epithelial cell differentiation

(2019) Vincenza De Gregorio et al.   BIOTECHNOLOGY AND BIOENGINEERING

3D stromal tissue equivalent affects intestinal epithelium morphogenesis in vitro

(2018) Vincenza De Gregorio et al.   BIOTECHNOLOGY AND BIOENGINEERING

Gut-liver on a chip towards an in vitro model of hepatic steatosis

(2018) Seung Yeon Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

A pumpless body-on-a-chip model using a primary culture of human intestinal cells and a 3D culture of liver cells

(2018) Huanhuan Joyce Chen et al.   LAB ON A CHIP

Micro-patterned endogenous stroma equivalent induces polarized crypt-villus architecture of human small intestinal epithelium

(2018) Vincenza De Gregorio et al.   Acta Biomaterialia

A three dimensional microfluidized liver system to assess hepatic drug metabolism and hepatotoxicity

(2018) Brunella Corrado et al.   BIOTECHNOLOGY AND BIOENGINEERING

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans

(2014) Jean Matthieu Prot et al.   BIOTECHNOLOGY AND BIOENGINEERING

Comparing the effects of acute alcohol consumption in germ-free and conventional mice: the role of the gut microbiota

(2014) Canesso MCC et al.   BMC MICROBIOLOGY

Pre-systemic metabolism of orally administered drugs and strategies to overcome it

(2014) Irene Pereira de Sousa et al.   JOURNAL OF CONTROLLED RELEASE

Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury

(2014) Mandy B. Esch et al.   LAB ON A CHIP

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

The role of microscaffold properties in controlling the collagen assembly in 3D dermis equivalent using modular tissue engineering

(2013) Giorgia Imparato et al.   BIOMATERIALS

Analysis and comparison of oxygen consumption of HepG2 cells in a monolayer and three-dimensional high density cell culture by use of a matrigrid®

(2013) Frank Weise et al.   BIOTECHNOLOGY AND BIOENGINEERING

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome

(2013) Corinne Ferrier Maurice et al.   CELL

Claudins and the Modulation of Tight Junction Permeability

(2013) Dorothee Günzel et al.   PHYSIOLOGICAL REVIEWS

Colonic microbiome is altered in alcoholism

(2012) Ece A. Mutlu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

On chip porous polymer membranes for integration of gastrointestinal tract epithelium with microfluidic ‘body-on-a-chip’ devices

(2012) Mandy Brigitte Esch et al.   BIOMEDICAL MICRODEVICES

Alcohol Metabolism

(2012) Arthur I. Cederbaum   Clinics in Liver Disease

The Role of Body-on-a-Chip Devices in Drug and Toxicity Studies

(2011) M.B. Esch et al.   Annual Review of Biomedical Engineering

Microfluidic cell culture models for tissue engineering

(2011) Niraj K Inamdar et al.   CURRENT OPINION IN BIOTECHNOLOGY

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices

(2010) Paul M. van Midwoud et al.   LAB ON A CHIP

Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity

(2009) Gretchen J. Mahler et al.   BIOTECHNOLOGY AND BIOENGINEERING