piggyBac-Based Non-Viral In Vivo Gene Delivery Useful for Production of Genetically Modified Animals and Organs

Production of Transgenic Porcine Embryos Reconstructed with Induced Pluripotent Stem-Like Cells Derived from Porcine Endogenous Factors Using piggyBac System

(2019) Su-Jin Kim et al.   Cellular Reprogramming

Prevention of cholestatic liver disease and reduced tumorigenicity in a murine model of PFIC type 3 using hybrid AAV‐ piggyBac gene therapy

(2019) S.M Siew et al.   HEPATOLOGY

In Vivo Piggybac-Based Gene Delivery towards Murine Pancreatic Parenchyma Confers Sustained Expression of Gene of Interest

(2019) Masahiro Sato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mapping of scaffold/matrix attachment regions in human genome: a data mining exercise

(2019) Nitin Narwade et al.   NUCLEIC ACIDS RESEARCH

Potential for Isolation of Immortalized Hepatocyte Cell Lines by Liver-Directed In Vivo Gene Delivery of Transposons in Mice

(2019) Masahiro Sato et al.   Stem Cells International

piggyBac Transposon-Based Immortalization of Human Deciduous Tooth Dental Pulp Cells with Multipotency and Non-Tumorigenic Potential

(2019) Emi Inada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Development of Functional Non-Viral Vectors for Gene Delivery

(2019) Patil et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transplacental Gene Delivery (TPGD) as a Noninvasive Tool for Fetal Gene Manipulation in Mice

(2019) Nakamura et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming

(2019) Lisa Kesselring et al.   NUCLEIC ACIDS RESEARCH

Long-term health and germline transmission in transgenic cattle following transposon-mediated gene transfer

(2018) Soo-Young Yum et al.   BMC GENOMICS

In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus

(2018) Jessica M. Rosin et al.   Journal of Neuroinflammation

Autologous Cell Therapy Approach for Duchenne Muscular Dystrophy using PiggyBac Transposons and Mesoangioblasts

(2018) Pavithra S. Iyer et al.   MOLECULAR THERAPY

Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo

(2018) Richard T. O’Neil et al.   Nature Communications

Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice

(2018) I-Ling Lu et al.   Nature Communications

HIV-1 inhibition in cells with CXCR4 mutant genome created by CRISPR-Cas9 and piggyBac recombinant technologies

(2018) Shuai Liu et al.   Scientific Reports

Novel Method of Plasmid DNA Delivery to Mouse Bladder Urothelium by Electroporation

(2018) Chuan Yu et al.   Jove-Journal of Visualized Experiments

Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells

(2018) Aslam Abbasi Akhtar et al.   Stem Cell Reports

Intravenous Delivery of piggyBac Transposons as a Useful Tool for Liver-Specific Gene-Switching

(2018) Shingo Nakamura et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers

(2017) Tyrel T. Smith et al.   Nature Nanotechnology

Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf−/−mouse model

(2017) Emilie A. Chapeau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of a transgenic cashmere goat using the piggyBac transposition system

(2017) Ding-Ping Bai et al.   THERIOGENOLOGY

Kidney-specific transposon-mediated gene transfer in vivo

(2017) Lauren E. Woodard et al.   Scientific Reports

Profiling of proteins secreted in the bovine oviduct reveals diverse functions of this luminal microenvironment

(2017) Viju Vijayan Pillai et al.   PLoS One

Matrix attachment region combinations increase transgene expression in transfected Chinese hamster ovary cells

(2017) Chun-Peng Zhao et al.   Scientific Reports

PiggyBac as a novel vector in cancer gene therapy: current perspective

(2016) H Mirzaei et al.   CANCER GENE THERAPY

Sleeping Beauty transposition: from biology to applications

(2016) Suneel A. Narayanavari et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

The impact of transposable elements on mammalian development

(2016) Jose L. Garcia-Perez et al.   DEVELOPMENT

Targeted in vivo genetic manipulation of the mouse or rat brain by in utero electroporation with a triple-electrode probe

(2016) Joanna Szczurkowska et al.   Nature Protocols

Efficient, footprint-free human iPSC genome editing by consolidation of Cas9/CRISPR and piggyBac technologies

(2016) Gang Wang et al.   Nature Protocols

Establishment of cell-based transposon-mediated transgenesis in cattle

(2016) Ana P. Alessio et al.   THERIOGENOLOGY

The Functionality of Minimal PiggyBac Transposons in Mammalian Cells

(2016) Boris Troyanovsky et al.   Molecular Therapy-Nucleic Acids

Efficient Production of Fluorescent Transgenic Rats using the piggyBac Transposon

(2016) Tianda Li et al.   Scientific Reports

Protective Role of Insulin-Like Growth Factor-1 Receptor in Endothelial Cells against Unilateral Ureteral Obstruction–Induced Renal Fibrosis

(2015) Ming Liang et al.   AMERICAN JOURNAL OF PATHOLOGY

Modeling correction of severe urea cycle defects in the growing murine liver using a hybrid recombinant adeno-associated virus/piggyBactransposase gene delivery system

(2015) Sharon C. Cunningham et al.   HEPATOLOGY

Hybrid Nonviral/Viral Vector Systems for Improved piggyBac DNA Transposon In Vivo Delivery

(2015) Ashley L Cooney et al.   MOLECULAR THERAPY

piggyBactransposons expressing full-length human dystrophin enable genetic correction of dystrophic mesoangioblasts

(2015) Mariana Loperfido et al.   NUCLEIC ACIDS RESEARCH

piggyBac-ing models and new therapeutic strategies

(2015) Lauren E. Woodard et al.   TRENDS IN BIOTECHNOLOGY

Roles of chromatin insulators in the formation of long-range contacts

(2015) Antoine Le Gall et al.   Nucleus

Roles of chromatin insulators in the formation of long-range contacts

(2015) Antoine Le Gall et al.   Nucleus

Liver Lobe and Strain Difference in Gene Expression After Hydrodynamics-Based Gene Delivery in Mice

(2014) Shingo Nakamura et al.   ANIMAL BIOTECHNOLOGY

Generation of Transgenic Pigs by Cytoplasmic Injection of piggyBac Transposase-Based pmGENIE-3 Plasmids1

(2014) Zicong Li et al.   BIOLOGY OF REPRODUCTION

Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy

(2014) Mario Di Matteo et al.   MOLECULAR THERAPY

Delivery of Full-Length Factor VIII Using a piggyBac Transposon Vector to Correct a Mouse Model of Hemophilia A

(2014) Hideto Matsui et al.   PLoS One

A PiggyBac-mediated approach for muscle gene transfer or cell therapy

(2014) Déborah Ley et al.   Stem Cell Research

piggyBac-mediated phenotypic correction of factor VIII deficiency

(2014) Janice M Staber et al.   Molecular Therapy-Methods & Clinical Development

piggyBac-mediated generation of stable transfectants with surface human leukocyte antigen expression from a small number of cells

(2013) Hiromi Miura et al.   ANALYTICAL BIOCHEMISTRY

Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition

(2013) Solenne Bire et al.   BMC BIOTECHNOLOGY

MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation

(2013) Stefania Puttini et al.   BMC MOLECULAR BIOLOGY

Generation of Transgenic Rats through Induced Pluripotent Stem Cells

(2013) Ming-Gui Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MAR Elements and Transposons for Improved Transgene Integration and Expression

(2013) Déborah Ley et al.   PLoS One

Optimization of the piggyBac Transposon Using mRNA and Insulators: Toward a More Reliable Gene Delivery System

(2013) Solenne Bire et al.   PLoS One

piggyBac transposase tools for genome engineering

(2013) X. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pig transgenesis by piggyBac transposition in combination with somatic cell nuclear transfer

(2013) Zhenfang Wu et al.   TRANSGENIC RESEARCH

PiggyBac Transposon-Mediated Gene Transfer in Cashmere Goat Fetal Fibroblast Cells

(2012) Ding-Ping BAI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits

(2012) Katharina Katter et al.   FASEB JOURNAL

A method for stable transgenesis of radial glia lineage in rat neocortex by piggyBac mediated transposition

(2012) Fuyi Chen et al.   JOURNAL OF NEUROSCIENCE METHODS

Hyperactive piggyBac Gene Transfer in Human Cells and In Vivo

(2011) Joseph E. Doherty et al.   HUMAN GENE THERAPY

Mobilization of giant piggyBac transposons in the mouse genome

(2011) Meng Amy Li et al.   NUCLEIC ACIDS RESEARCH

A hyperactive piggyBac transposase for mammalian applications

(2011) K. Yusa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The expanding universe of transposon technologies for gene and cell engineering

(2011) Zoltán Ivics et al.   Mobile DNA

piggyBac Transposon-mediated Long-term Gene Expression in Mice

(2010) Hideyuki Nakanishi et al.   MOLECULAR THERAPY

Cytoplasmic injection of circular plasmids allows targeted expression in mammalian embryos

(2009) Khursheed Iqbal et al.   BIOTECHNIQUES

An Efficient and Reversible Transposable System for Gene Delivery and Lineage-Specific Differentiation in Human Embryonic Stem Cells

(2009) Arnaud Lacoste et al.   Cell Stem Cell

Chromosomal mobilization and reintegration ofSleeping BeautyandPiggyBactransposons

(2009) Qi Liang et al.   GENESIS

A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells

(2009) W. Wang et al.   GENOME RESEARCH

PiggyBac Transposon-based Inducible Gene Expression In Vivo After Somatic Cell Gene Transfer

(2009) Sai K Saridey et al.   MOLECULAR THERAPY

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

(2009) Knut Woltjen et al.   NATURE

Chromosomal transposition of PiggyBac in mouse embryonic stem cells

(2008) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA