An Interspecies Molecular and Functional Study of Organic Cation Transporters at the Blood-Brain Barrier: From Rodents to Humans

A molecular atlas of cell types and zonation in the brain vasculature

(2018) Michael Vanlandewijck et al.   NATURE

LC–MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line

(2017) Laura Pelkonen et al.   MOLECULAR PHARMACEUTICS

Effect of Subchronic Intravenous Morphine Infusion and Naloxone-Precipitated Morphine Withdrawal on P-gp and Bcrp at the Rat Blood–Brain Barrier

(2016) Catarina Chaves et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Poorly Membrane Permeable Antipsychotic Drugs Amisulpride and Sulpiride Are Substrates of the Organic Cation Transporters from the SLC22 Family

(2014) Joao N. Dos Santos Pereira et al.   AAPS Journal

P-glycoprotein induction in Caco-2 cells by newly synthetized thioxanthones prevents paraquat cytotoxicity

(2014) Renata Silva et al.   ARCHIVES OF TOXICOLOGY

Decreased Expression of Organic Cation Transporters, Oct1 and Oct2, in Brain Microvessels and its Implication to MPTP-Induced Dopaminergic Toxicity in Aged Mice

(2014) Kuo-Chen Wu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Profiling Solute Carrier Transporters in the Human Blood–Brain Barrier

(2013) E G Geier et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

RBE4 cells are highly resistant to paraquat-induced cytotoxicity: studies on uptake and efflux mechanisms

(2013) V. Vilas-Boas et al.   JOURNAL OF APPLIED TOXICOLOGY

Role of the Plasma Membrane Transporter of Organic Cations OCT1 and Its Genetic Variants in Modern Liver Pharmacology

(2013) Elisa Lozano et al.   Biomed Research International

Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics

(2012) D R Mani et al.   BMC BIOINFORMATICS

Transport of Biogenic Amine Neurotransmitters at the Mouse Blood–Retina and Blood–Brain Barriers by Uptake1 and Uptake2

(2012) Pascal André et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lamotrigine is a substrate for OCT1 in brain endothelial cells

(2011) David Dickens et al.   BIOCHEMICAL PHARMACOLOGY

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Functional characterization of Rat Plasma Membrane Monoamine Transporter in the Blood–Brain and Blood–Cerebrospinal Fluid Barriers

(2011) Takashi Okura et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels

(2011) Ramzi Shawahna et al.   MOLECULAR PHARMACEUTICS

Assessment of Fetal Brain Uptake of Paraquat In Utero Using In Vivo PET/CT Imaging

(2011) Rachel M. Bartlett et al.   TOXICOLOGICAL SCIENCES

Effect of Collision Energy Optimization on the Measurement of Peptides by Selected Reaction Monitoring (SRM) Mass Spectrometry

(2010) Brendan MacLean et al.   ANALYTICAL CHEMISTRY

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

Cellular localization of the organic cation transporters, OCT1 and OCT2, in brain microvessel endothelial cells and its implication for MPTP transport across the blood-brain barrier and MPTP-induced dopaminergic toxicity in rodents

(2010) Chun-Jung Lin et al.   JOURNAL OF NEUROCHEMISTRY

Culture-Induced Changes in Blood—Brain Barrier Transcriptome: Implications for Amino-Acid Transporters in vivo

(2009) Ruth Lyck et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Paraquat is excluded by the blood brain barrier in rhesus macaque: An in vivo pet study

(2008) Rachel M. Bartlett et al.   BRAIN RESEARCH

In Situ Mouse Carotid Perfusion Model: Glucose and Cholesterol Transport in the Eye and Brain

(2008) Julie Cattelotte et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effect of chronic exposure to morphine on the rat blood-brain barrier: focus on the P-glycoprotein

(2008) Salah Yousif et al.   JOURNAL OF NEUROCHEMISTRY

Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria

(2008) Junichi Kamiie et al.   PHARMACEUTICAL RESEARCH