The Pan-Sirtuin Inhibitor MC2494 Regulates Mitochondrial Function in a Leukemia Cell Line

Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype

(2019) Vincenzo Carafa et al.   Frontiers in Pharmacology

Mitochondria in Health and Disease

(2019) Sarah J. Annesley et al.   Cells

Macrophage Migration Inhibitory Factor Is a Molecular Determinant of the Anti-EGFR Monoclonal Antibody Cetuximab Resistance in Human Colorectal Cancer Cells

(2019) Rosita Russo et al.   Cancers

Enzymatic and Biological Characterization of Novel Sirtuin Modulators against Cancer

(2019) Vincenzo Carafa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The striatal-enriched protein Rhes is a critical modulator of cocaine-induced molecular and behavioral responses

(2019) Francesco Napolitano et al.   Scientific Reports

RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer

(2018) Vincenzo Carafa et al.   CLINICAL CANCER RESEARCH

Mitochondria in health and disease

(2018) Sanjiban Chakrabarty et al.   MITOCHONDRION

Mitochondrial OXPHOS complex assembly lines

(2018) Luke E. Formosa et al.   NATURE CELL BIOLOGY

Intra-mitochondrial biomineralization for inducing apoptosis of cancer cells

(2018) Sangpil Kim et al.   Chemical Science

The roles of sirtuins family in cell metabolism during tumor development

(2018) Shunqin Zhu et al.   SEMINARS IN CANCER BIOLOGY

Functional Mitochondria in Health and Disease

(2017) Patries M. Herst et al.   Frontiers in Endocrinology

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

p53 pathway dysfunction is highly prevalent in acute myeloid leukemia independent of TP53 mutational status

(2016) A Quintás-Cardama et al.   LEUKEMIA

The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression

(2016) Jiandong Chen   Cold Spring Harbor Perspectives in Medicine

Sirtuin functions and modulation: from chemistry to the clinic

(2016) Vincenzo Carafa et al.   Clinical Epigenetics

The role of mammalian sirtuins in cancer metabolism

(2015) Carlos Sebastián et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

(2014) Valerie S. LeBleu et al.   NATURE CELL BIOLOGY

Cancer as a metabolic disease: implications for novel therapeutics

(2013) T. N. Seyfried et al.   CARCINOGENESIS

p53 Orchestrates the PGC-1α-Mediated Antioxidant Response Upon Mild Redox and Metabolic Imbalance

(2012) Katia Aquilano et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT1, Is It a Tumor Promoter or Tumor Suppressor?

(2012) Chu-Xia Deng   International Journal of Biological Sciences

PGC1  and mitochondrial metabolism - emerging concepts and relevance in ageing and neurodegenerative disorders

(2012) S. Austin et al.   JOURNAL OF CELL SCIENCE

Sirtuins and Disease: The Road Ahead

(2012) Vincenzo Carafa et al.   Frontiers in Pharmacology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

PGC-1α, a Key Modulator of p53, Promotes Cell Survival upon Metabolic Stress

(2011) Nirmalya Sen et al.   MOLECULAR CELL

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

(2010) Eric Verdin et al.   TRENDS IN BIOCHEMICAL SCIENCES